Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Erika T. Brown"'
Autor:
John J. Skoko, Juxiang Cao, David Gaboriau, Myriam Attar, Alparslan Asan, Lisa Hong, Candice E. Paulsen, Hongqiang Ma, Yang Liu, Hanzhi Wu, Trey Harkness, Cristina M. Furdui, Yefim Manevich, Ciaran G. Morrison, Erika T. Brown, Daniel Normolle, Maria Spies, Michael Ashley Spies, Kate Carroll, Carola A. Neumann
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102443- (2022)
RAD51 is a critical recombinase that functions in concert with auxiliary mediator proteins to direct the homologous recombination (HR) DNA repair pathway. We show that Cys319 RAD51 possesses nucleophilic characteristics and is important for irradiati
Externí odkaz:
https://doaj.org/article/2fc66d80d6fa4b56ae9f41a240a26b8a
Autor:
Joan E. Cunningham, Dana R. Burshell, Deborah Hurley, Angela M. Malek, Leslie A. Moore, Erika T. Brown, Colleen E. Bauza, Latecia M. Abraham, Catishia Mosley, Franshawn Mack, Susan Bolick, David P. Turner, Nestor F. Esnaola, Lindsay L. Peterson, Anthony J. Alberg, Kendrea D. Knight, Victoria J. Findlay, Mathew J. Gregoski, Lourdes M. Nogueira, Judith D. Salley, Tonya R. Hazelton, Keith E. Whitfield, Ebony J. Hilton, Marvella E Ford, Rita Kramer, Kadeidre Gaymon, Gayenell S. Magwood
Publikováno v:
Adv Cancer Res
Higher BMI, lower rates of physical activity (PA), and hormone receptor-negative breast cancer (BC) subtype are associated with poorer BC treatment outcomes. We evaluated the prevalence of high BMI, low PA level, and BC subtype among survivors with w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1d0bf1ec672406a10c41f93501e7a6
https://doi.org/10.1016/bs.acr.2020.01.005
https://doi.org/10.1016/bs.acr.2020.01.005
Autor:
Leslie A. Moore, Colleen E. Bauza, Susan Bolick, Franshawn Mack, Keith E. Whitfield, Victoria J. Findlay, Catishia Mosley, Latecia Monicque Abraham-Hilaire, Angela M. Malek, Ebony J. Hilton, Dana R. Burshell, Joan E. Cunningham, Rita Kramer, Gayenell S. Magwood, Anthony J. Alberg, Marvella E. Ford, Deborah Hurley, Erika T. Brown, Lindsay L. Peterson, Tonya R. Hazelton, Kadeidre Gaymon, Kendrea D. Knight, Lourdes M. Nogueira, Judith D. Salley, David P. Turner
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:B102-B102
BACKGROUND: Breast cancer (BCa) is the second leading cause of cancer death among women in the United States and large racial/ethnic disparities are evident. Higher levels of body mass index (BMI), lower rates of physical activity (PA), and hormone r
Autor:
David C. A. Gaboriau, Steven R. Woodcock, Carola A. Neumann, Erika T. Brown, Yefim Manevich, Ciaran G. Morrison, Yang Liu, Hongqiang Ma, Alparslan Asan, Bentley M. Wingert, Juxiang Cao, Kate S. Carroll, Myriam A. Attar, Carlos J. Camacho, John J. Skoko, Candice E. Paulsen, Chen Shan C. Woodcock, Bruce A. Freeman, Jennifer Schulte
Publikováno v:
SSRN Electronic Journal.
Peroxiredoxin 1 (PRDX1) senses and reduces peroxides and coordinates the signaling actions of its binding partners. We show that PRDX1 protects RAD51 from oxidation-induced repression of homologous recombination (HR) repair following ɣ-irradiation.
Autor:
Rita Kramer, Gayenell S. Magwood, Erika T. Brown, Lindsay L. Peterson, Ashley Evans-Knowell, David P. Turner, Kendrea D. Knight, Kimberly Cannady, Marvella E. Ford, Mathew J. Gregoski
The significantly higher breast cancer (BCa) mortality rates of African-American (AA) women compared to non-Hispanic (NHW) white women constitute a major US health disparity. Investigations have primarily focused on biological differences in tumors t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ee2528741cfc6022528b5d2d58b565
https://doi.org/10.1016/bs.acr.2016.08.002
https://doi.org/10.1016/bs.acr.2016.08.002
Autor:
Rita Kramer, DC Bryant, Emily Kistner-Griffin, S Bolick, Burshell, IJ Spruill, C Mosley, Anthony J. Alberg, Jefferson, Erika T. Brown, TR Hazelton, Keith E. Whitfield, CE Bauza, Vivian J. Bea, KD Charles, Nestor F. Esnaola, Marvella E. Ford, Joan E. Cunningham, D Hurley
Publikováno v:
Cancer Research. 73:P5-12
Introduction: Overweight/obesity are associated with higher risk of recurrence and poorer survival after a breast cancer diagnosis. According to The Centers for Disease Control and Prevention (CDC) Behavioral Risk Factor Surveillance System (BRFSS) d
Autor:
Judith D. Salley, Rita Kramer, Deborah Hurley, Anthony J. Alberg, Victoria J. Findlay, Susan Bolick, Marvella E. Ford, David P. Turner, Joan E. Cunningham, Nestor F. Esnaola, Erika T. Brown
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 27:A24-A24
Background: Blacks in the U.S. have the worst breast cancer survival outcomes of any racial/ethnic group in the nation. However, blacks are not a monolithic group but are comprised of several ethnic groups. One such group in particular is the Sea Isl
Publikováno v:
Cancer Genetics and Cytogenetics. 186:85-94
Mutations in the BRCA2 gene are associated with inherited, early-onset breast cancer. CAPAN-1 cells have been very beneficial in studying how BRCA2 mutations contribute to malignant transformation. They exhibit loss of heterozygosity (LOH), and the r
Publikováno v:
Radiation Research. 169:595-601
Brown, E. T., Robinson-Benion, C. and Holt, J. T. Radiation Enhances Caspase 3 Cleavage of Rad51 in BRCA2-Defective Cells. Radiat. Res. 169, 595–601 (2008). After DNA damage, caspases cleave and activate proteins involved in cell death by apoptosis
Autor:
Markus C. Fleisch, Mary Helen Barcellos-Hoff, Sylvain V. Costes, Claudia K. Kuper, Christopher A. Maxwell, Erika T. Brown
Publikováno v:
Microscopy Research and Technique. 69:964-972
Centrosomes are small organelles that organize the mitotic spindle during cell division and are also involved in cell shape and polarity. Within epithelial tumors, such as breast cancer, and some hematological tumors, centrosome abnormalities (CAs) a