Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Erika Orbán"'
Autor:
Emese Gál, Antal Csámpai, Erika Orbán, Pál Sohár, László Drahos, Benedek Imre Károlyi, Szilvia Bősze
Publikováno v:
Molecules, Vol 17, Iss 3, Pp 2316-2329 (2012)
A series of novel functionalized mono-, bis- and tris-(S)-{[(2S,4R,8R)-8-ethyl-quinuclidin-2-yl](6-methoxyquinolin-4-yl)}methanamines including ferrocene-containing derivatives was obtained by the reaction of the precursor amine with a variety of acy
Externí odkaz:
https://doaj.org/article/31e205812e644e679b2b5043aec30804
Publikováno v:
ARKIVOC, Vol 2008, Iss 3, Pp 140-153 (2008)
Externí odkaz:
https://doaj.org/article/352612da0ddc4187a3bc73eb9506bd49
Autor:
Verena Natalie Schreier, Lilla Pethő, Erika Orbán, Andreas Marquardt, Brindusa Alina Petre, Gábor Mező, Marilena Manea
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94041 (2014)
Targeted delivery of chemotherapeutic agents is a new approach for the treatment of cancer, which provides increased selectivity and decreased systemic toxicity. We have recently developed a promising drug delivery system, in which the anticancer dru
Externí odkaz:
https://doaj.org/article/2f955200099c4258876116c04b7871a6
Publikováno v:
European Journal of Medicinal Chemistry. 115:361-368
The emerging resistance of tumor cells against methotrexate (MTX) is one of the major limitations of the MTX treatment of tumorous diseases. The disturbance in the polyglutamation which is a main step in the mechanism of methotrexate action is often
Publikováno v:
Tetrahedron Letters. 57:868-873
Cholesteryl lipoprotein semisynthesis was accomplished via a copper-catalyzed azide–alkyne cycloaddition on the surface of live cells. In this convergent synthesis an azido-cholesterol was introduced into the cell membrane without the application o
Autor:
Gabor Halmos, Erika Orbán, Gábor Mező, Ildikó Szabó, Magdolna Kovacs, Éva Sipos, Szilvia Bősze
Publikováno v:
Journal of Peptide Science. 21:426-435
Hormone based drug targeting is a promising tool for selective tumor therapy. In this study, synthesis and systematic comparative biological evaluation of novel drug containing analogs of gonadotropin-releasing hormone GnRH-I and GnRH-II is reported
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 58:7-13
Cell membrane association of proteins can be achieved by the addition of lipid moieties to the polypeptide chain, and such lipid-modified proteins have important biological functions. A class of cell surface proteins contains a complex glycosylphosph
Publikováno v:
Engineering in Life Sciences. 14:365-379
Membrane proteins (MPs) are of central interest for the pharmaceutical industry but their production is usually a challenging task. The complex folding mechanisms of newly synthesized MPs often require interactions with specific compounds for improve
Autor:
Krisztina Huszár, Ervin Welker, Csaba Tömböly, Erika Orbán, Balázs Schäfer, Antal Nyeste, Attila Borics
Publikováno v:
Bioconjugate Chemistry. 24:1684-1697
The exogenous introduction of fluorescent lipoproteins into cell membranes is a method for visualizing the cellular traffic of membrane associated proteins, and also for altering the cell surface in a controlled manner. In order to achieve the cell m
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 31:482-500
A series of new 5-halogeno-1-(ß-L-arabinofuranosyl)uracils and their cytosine analogues were synthesized by halogenation of ara-L-uridine and ara-L-cytidine, respectively. The 5-(2-thienyl) and 5-halogenothienyl derivatives of both series were also