Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Erika Orbán"'
Autor:
Emese Gál, Antal Csámpai, Erika Orbán, Pál Sohár, László Drahos, Benedek Imre Károlyi, Szilvia Bősze
Publikováno v:
Molecules, Vol 17, Iss 3, Pp 2316-2329 (2012)
A series of novel functionalized mono-, bis- and tris-(S)-{[(2S,4R,8R)-8-ethyl-quinuclidin-2-yl](6-methoxyquinolin-4-yl)}methanamines including ferrocene-containing derivatives was obtained by the reaction of the precursor amine with a variety of acy
Externí odkaz:
https://doaj.org/article/31e205812e644e679b2b5043aec30804
Publikováno v:
ARKIVOC, Vol 2008, Iss 3, Pp 140-153 (2008)
Externí odkaz:
https://doaj.org/article/352612da0ddc4187a3bc73eb9506bd49
Autor:
Verena Natalie Schreier, Lilla Pethő, Erika Orbán, Andreas Marquardt, Brindusa Alina Petre, Gábor Mező, Marilena Manea
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94041 (2014)
Targeted delivery of chemotherapeutic agents is a new approach for the treatment of cancer, which provides increased selectivity and decreased systemic toxicity. We have recently developed a promising drug delivery system, in which the anticancer dru
Externí odkaz:
https://doaj.org/article/2f955200099c4258876116c04b7871a6
Autor:
Gabor Halmos, Erika Orbán, Gábor Mező, Ildikó Szabó, Magdolna Kovacs, Éva Sipos, Szilvia Bősze
Publikováno v:
Journal of Peptide Science. 21:426-435
Hormone based drug targeting is a promising tool for selective tumor therapy. In this study, synthesis and systematic comparative biological evaluation of novel drug containing analogs of gonadotropin-releasing hormone GnRH-I and GnRH-II is reported
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 58:7-13
Cell membrane association of proteins can be achieved by the addition of lipid moieties to the polypeptide chain, and such lipid-modified proteins have important biological functions. A class of cell surface proteins contains a complex glycosylphosph
Publikováno v:
Engineering in Life Sciences. 14:365-379
Membrane proteins (MPs) are of central interest for the pharmaceutical industry but their production is usually a challenging task. The complex folding mechanisms of newly synthesized MPs often require interactions with specific compounds for improve
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 31:482-500
A series of new 5-halogeno-1-(ß-L-arabinofuranosyl)uracils and their cytosine analogues were synthesized by halogenation of ara-L-uridine and ara-L-cytidine, respectively. The 5-(2-thienyl) and 5-halogenothienyl derivatives of both series were also
Autor:
Benedek Imre Károlyi, Emese Gal, Szilvia Bösze, Pál Sohár, Antal Csámpai, Erika Orbán, László Drahos
Publikováno v:
Molecules, Vol 17, Iss 3, Pp 2316-2329 (2012)
Molecules; Volume 17; Issue 3; Pages: 2316-2329
Molecules
Molecules; Volume 17; Issue 3; Pages: 2316-2329
Molecules
A series of novel functionalized mono-, bis- and tris-(S)-{[(2S,4R,8R)-8-ethyl-quinuclidin-2-yl](6-methoxyquinolin-4-yl)}methanamines including ferrocene-containing derivatives was obtained by the reaction of the precursor amine with a variety of acy
Autor:
Zoltán Bánóczi, Erzsébet Fellinger, Erika Orbán, Szilvia Bösze, Ferenc Hudecz, Gabriella Csík, Marilena Manea, Andreas Marquadt
Publikováno v:
Bioconjugate Chemistry. 22:2154-2165
Daunomycin (Dau) is a DNA-binding antineoplastic agent in the treatment of various types of cancer, such as osteosarcomas and acute myeloid leukemia. One approach to improve its selectivity and to decrease the side effects is the conjugation of Dau w
Autor:
Bence Kapuvári, Andreas Marquardt, Marilena Manea, Zsuzsa Baranyai, Ulrike Leurs, József Tóvári, Erika Orbán, Ákos Schulcz, Peter Öhlschläger, Gábor Mezö, Miguel Tejeda
Publikováno v:
Bioconjugate Chemistry. 22:1320-1329
Here, we report on the synthesis, enzymatic stability, and antitumor activity of novel bioconjugates containing the chemotherapeutic agent daunorubicin attached through an oxime bond to various gonadotropin-releasing hormone-III (GnRH-III) derivative