Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Erika Nieddu"'
Autor:
Benedetta Pollarolo, M. Mazzei, Luis J. V. Galietta, Erika Nieddu, Maria Anzaldi, Mauro Mazzei, Silvia Schenone, Nicoletta Pedemonte
Publikováno v:
Archiv der Pharmazie. 349:112-123
The phenylhydrazone RDR-1 is endowed with moderate activity as F508del-CFTR corrector; nevertheless, its simple structure enables stimulating developments in this class of correctors. Therefore, we synthesized a number of phenylhydrazones 3 by reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c3ad98e2d4821395e186f84ab70bb48
https://doi.org/10.1002/ardp.201500352
https://doi.org/10.1002/ardp.201500352
Autor:
Cinzia Domenicotti, Benedetta Pollarolo, Francesca Musumeci, Andrea Speciale, Mauro Mazzei, Lisa Senatore, Barbara Marengo, Silvano Garibaldi, Maria Adelaide Pronzato, Silvia Schenone, Erika Nieddu
Publikováno v:
Molecular Medicine Reports
Cystic fibrosis is caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and the predominant mutation is termed Phe508del (F508del). Therapy for F508del‑CFTR patients is based on the use of Orkambi®, a combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6dc270abac54d48fc563966a8ea8af
http://hdl.handle.net/11567/877175
http://hdl.handle.net/11567/877175
Autor:
Luis J. V. Galietta, Erika Nieddu, Benedetta Pollarolo, Mauro Mazzei, M. Mazzei, Maria Anzaldi, Emanuela Pesce, Silvia Schenone, Nicoletta Pedemonte
Publikováno v:
Future Medicinal Chemistry. 6:1857-1868
Background: The F508del mutation impairs the trafficking of CFTR from endoplasmic reticulum to plasma membrane and is responsible of a severe form of cystic fibrosis. Trafficking can be improved by small organic molecules called 'correctors'. Materia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98828f857079bccd633a54d1e6961a3f
https://doi.org/10.4155/fmc.14.118
https://doi.org/10.4155/fmc.14.118
Publikováno v:
Understanding and Exploiting Protein–Protein Interactions as Drug Targets. :46-60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b21d797b17522402779f0404563ef1b2
https://doi.org/10.4155/ebo.13.142
https://doi.org/10.4155/ebo.13.142
Autor:
Erika, Nieddu, Benedetta, Pollarolo, Marco T, Mazzei, Maria, Anzaldi, Silvia, Schenone, Nicoletta, Pedemonte, Luis J V, Galietta, Mauro, Mazzei
The phenylhydrazone RDR-1 is endowed with moderate activity as F508del-CFTR corrector; nevertheless, its simple structure enables stimulating developments in this class of correctors. Therefore, we synthesized a number of phenylhydrazones 3 by reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9dd40c55159ffbeaba1a97368ee9c547
http://hdl.handle.net/11588/728871
http://hdl.handle.net/11588/728871
Autor:
Piergiorgio Gentile, Gianluca Ciardelli, Valeria Balbo, Erika Nieddu, L. Mazzucco, T. Benko, R. Mandrile
Publikováno v:
Reactive and Functional Polymers. 69:371-379
Purpose Perspective applications of nanocomposites in biomedical applications are investigated in this work by producing intercalated dispersions of clays into a biodegradable polymer matrix. Poly(lactic acid) (PLA) was selected being produced from r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5cdf86e088a4400f1b3e9093c8222e
https://doi.org/10.1016/j.reactfunctpolym.2009.03.002
https://doi.org/10.1016/j.reactfunctpolym.2009.03.002
Autor:
Paolo La Colla, M. Mazzei, Fabio Marongiu, Maurizio Fermeglia, Erika Nieddu, Marco Ferrone, Mauro Mazzei, Mariangela Miele, Cristina Ibba, Alessandro Balbi, Sabrina Pricl, Roberta Loddo
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:2591-2605
Some Mannich bases of 7-hydroxycoumarin (2) and their simple derivatives (3 and 4) were prepared and tested against viruses containing single-stranded, positive-sense RNA genomes (ssRNA(+)). This study was directed toward Flaviviridae and, in particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865bd43a286f5b047cb6e9e251e22c72
https://doi.org/10.1016/j.bmc.2007.11.045
https://doi.org/10.1016/j.bmc.2007.11.045
Autor:
Erika, Nieddu
Publikováno v:
Current pharmaceutical design. 19(19)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d4e26e9f8a37afdb0f948f7bdbf59ca
https://pubmed.ncbi.nlm.nih.gov/23331031
https://pubmed.ncbi.nlm.nih.gov/23331031
Autor:
Mauro Mazzei, M. Mazzei, Erika Nieddu, Nicolas Vanthuyne, Christian Roussel, Luis J. V. Galietta, Michele Giampieri, Nicoletta Pedemonte, Maria Anzaldi
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2012, 7 (10), pp.1799-1807. ⟨10.1002/cmdc.201200311⟩
ChemMedChem, 2012, 7 (10), pp.1799-1807. ⟨10.1002/cmdc.201200311⟩
ChemMedChem, Wiley-VCH Verlag, 2012, 7 (10), pp.1799-1807. ⟨10.1002/cmdc.201200311⟩
ChemMedChem, 2012, 7 (10), pp.1799-1807. ⟨10.1002/cmdc.201200311⟩
Some of the genetic mutations that cause cystic fibrosis (CF) impair the gating of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) ion channel. This defect can be corrected with pharmacological tools (potentiators) that belong to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3650d4fcb688144272882d1a51f6b174
https://hal.archives-ouvertes.fr/hal-02517561
https://hal.archives-ouvertes.fr/hal-02517561
Autor:
M. Mazzei, Erika Nieddu, Maria Pascale, Mauro Mazzei, Maria Caterina Turco, Anna Basile, Silvia Franceschelli, Paola Fossa
Publikováno v:
Journal of cellular physiology. 227(9)
Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-dependent Cl− channel located in the plasma membrane, and its malfunction results in cystic fibrosis (CF), the most common lethal genetic disease in Caucasians. Most CF patients c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57aa9d7598f915c6b2a40441909145be
https://pubmed.ncbi.nlm.nih.gov/22170045
https://pubmed.ncbi.nlm.nih.gov/22170045