Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Erika N. Scott"'
Autor:
Erika N. Scott, Galen E. B. Wright, Britt I. Drögemöller, Jafar S. Hasbullah, Erandika P. Gunaretnam, Fudan Miao, Amit P. Bhavsar, Fei Shen, Bryan P. Schneider, Bruce C. Carleton, Colin J. D. Ross
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Anthracyclines are highly effective chemotherapeutic agents; however, their clinical utility is limited by severe anthracycline-induced cardiotoxicity (ACT). Genome-wide association studies (GWAS) have uncovered several genetic variants asso
Externí odkaz:
https://doaj.org/article/ef67d46dd6034a2687778555b536d940
Autor:
Jafar S Hasbullah, Erika N Scott, Amit P Bhavsar, Erandika P Gunaretnam, Fudan Miao, Hesham Soliman, Bruce C Carleton, Colin J D Ross
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276541 (2022)
The effectiveness of anthracycline chemotherapeutics (e.g., doxorubicin) is limited by anthracycline-induced cardiotoxicity (ACT). A nonsynonymous variant (S427L) in the retinoic acid receptor-γ (RARG) gene has been associated with ACT. This variant
Externí odkaz:
https://doaj.org/article/aab2c73896e040bcaf32a205127ff72f
Autor:
Etan Orgel, Kristin R. Knight, Yueh-Yun Chi, Jemily Malvar, Teresa Rushing, Victoria Mena, Laurie S. Eisenberg, Shahrad R. Rassekh, Colin J.D. Ross, Erika N. Scott, Michael Neely, Edward A. Neuwelt, Leslie L. Muldoon, David R. Freyer
Publikováno v:
Clinical Cancer Research. :OF1-OF9
Purpose: Cisplatin-induced hearing loss (CIHL) is common and permanent. As compared with earlier otoprotectants, we hypothesized N-acetylcysteine (NAC) offers potential for stronger otoprotection through stimulation of glutathione (GSH) production. T
Autor:
David R. Freyer, Leslie L. Muldoon, Edward A. Neuwelt, Michael Neely, Erika N. Scott, Colin J.D. Ross, Shahrad R. Rassekh, Laurie S. Eisenberg, Victoria Mena, Teresa Rushing, Jemily Malvar, Yueh-Yun Chi, Kristin R. Knight, Etan Orgel
Supplementary Fig. 1 Treatment schema & Sampling Timepoints
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a85604fb159dba9c1bb7bbc901a53c3
https://doi.org/10.1158/1078-0432.23183875.v1
https://doi.org/10.1158/1078-0432.23183875.v1
Autor:
David R. Freyer, Leslie L. Muldoon, Edward A. Neuwelt, Michael Neely, Erika N. Scott, Colin J.D. Ross, Shahrad R. Rassekh, Laurie S. Eisenberg, Victoria Mena, Teresa Rushing, Jemily Malvar, Yueh-Yun Chi, Kristin R. Knight, Etan Orgel
Supplementary Fig. 4 Evaluation of long-term storage of serum specimens (NAC assay)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd1cd760e6df37bf5c89a50e73ee9c2
https://doi.org/10.1158/1078-0432.23183866.v1
https://doi.org/10.1158/1078-0432.23183866.v1
Autor:
David R. Freyer, Leslie L. Muldoon, Edward A. Neuwelt, Michael Neely, Erika N. Scott, Colin J.D. Ross, Shahrad R. Rassekh, Laurie S. Eisenberg, Victoria Mena, Teresa Rushing, Jemily Malvar, Yueh-Yun Chi, Kristin R. Knight, Etan Orgel
Supplementary Fig. 3 Change in serum glutathione concentrations following NAC infusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9412af11ef1fc54eaecda89a9f4181
https://doi.org/10.1158/1078-0432.23183869.v1
https://doi.org/10.1158/1078-0432.23183869.v1
Autor:
David R. Freyer, Leslie L. Muldoon, Edward A. Neuwelt, Michael Neely, Erika N. Scott, Colin J.D. Ross, Shahrad R. Rassekh, Laurie S. Eisenberg, Victoria Mena, Teresa Rushing, Jemily Malvar, Yueh-Yun Chi, Kristin R. Knight, Etan Orgel
Supplementary Fig. 5 Progression-free survival in NAC treated and observation patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1c7b9e98c7edbb3286e380ea49eff0
https://doi.org/10.1158/1078-0432.23183863
https://doi.org/10.1158/1078-0432.23183863
Autor:
David R. Freyer, Leslie L. Muldoon, Edward A. Neuwelt, Michael Neely, Erika N. Scott, Colin J.D. Ross, Shahrad R. Rassekh, Laurie S. Eisenberg, Victoria Mena, Teresa Rushing, Jemily Malvar, Yueh-Yun Chi, Kristin R. Knight, Etan Orgel
Supplementary Fig. 2 Cumulative incidence of SIOP Grade ≥2 hearing loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6ed299a5f2d95efbbd116f396d3f6f
https://doi.org/10.1158/1078-0432.23183872
https://doi.org/10.1158/1078-0432.23183872
Autor:
David R. Freyer, Leslie L. Muldoon, Edward A. Neuwelt, Michael Neely, Erika N. Scott, Colin J.D. Ross, Shahrad R. Rassekh, Laurie S. Eisenberg, Victoria Mena, Teresa Rushing, Jemily Malvar, Yueh-Yun Chi, Kristin R. Knight, Etan Orgel
Supplemental Tables and Files
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0399d2e457c2888977bd3885e0c4d9e9
https://doi.org/10.1158/1078-0432.23183878.v1
https://doi.org/10.1158/1078-0432.23183878.v1
Autor:
David R. Freyer, Leslie L. Muldoon, Edward A. Neuwelt, Michael Neely, Erika N. Scott, Colin J.D. Ross, Shahrad R. Rassekh, Laurie S. Eisenberg, Victoria Mena, Teresa Rushing, Jemily Malvar, Yueh-Yun Chi, Kristin R. Knight, Etan Orgel
Purpose:Cisplatin-induced hearing loss (CIHL) is common and permanent. As compared with earlier otoprotectants, we hypothesized N-acetylcysteine (NAC) offers potential for stronger otoprotection through stimulation of glutathione (GSH) production. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb2b2f3858f2b097b2b25d33936abba
https://doi.org/10.1158/1078-0432.c.6664582.v1
https://doi.org/10.1158/1078-0432.c.6664582.v1