Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Erika M. Gaglione"'
Autor:
Christoph Rader, Adrian Wiestner, Jing Chang, Matthew G Cyr, Maissa Mhibik, Junpeng Qi, Haiyong Peng, Erika M Gaglione, David Eik, John Herrick, Thomas Venables, Scott J Novick, Valentine V Courouble, Patrick R Griffin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)
Background Despite numerous therapeutic options, safe and curative therapy is unavailable for most patients with chronic lymphocytic leukemia (CLL). A drawback of current therapies such as the anti-CD20 monoclonal antibody (mAb) rituximab is the elim
Externí odkaz:
https://doaj.org/article/540fafe660a248c8baf6af7c92d6611f
Autor:
Anfal Alsadhan, Jonathan Chen, Erika M. Gaglione, Chingiz Underbayev, Pamela L. Tuma, Xin Tian, Lita A. Freeman, Sivasubramanian Baskar, Pia Nierman, Susan Soto, Andy Itsara, Inhye E. Ahn, Clare Sun, Elena Bibikova, Tanja Nicole Hartmann, Maissa Mhibik, Adrian Wiestner
Publikováno v:
Clinical Cancer Research. :OF1-OF10
Purpose: To determine the role of CD49d for response to Bruton's tyrosine kinase inhibitors (BTKi) in patients with chronic lymphocytic leukemia (CLL). Patients and Methods: In patients treated with acalabrutinib (n = 48), CD49d expression, VLA-4 int
Autor:
Adrian Wiestner, Maissa Mhibik, Tanja Nicole Hartmann, Elena Bibikova, Clare Sun, Inhye E. Ahn, Andy Itsara, Susan Soto, Pia Nierman, Sivasubramanian Baskar, Lita A. Freeman, Xin Tian, Pamela L. Tuma, Chingiz Underbayev, Erika M. Gaglione, Jonathan Chen, Anfal Alsadhan
Supplementary Figure S4. Clinical impact of CD49d bimodal expression on durability of BTKi therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6e2f143a919314888e8db503217f33
https://doi.org/10.1158/1078-0432.23183864.v1
https://doi.org/10.1158/1078-0432.23183864.v1
Autor:
Adrian Wiestner, Maissa Mhibik, Tanja Nicole Hartmann, Elena Bibikova, Clare Sun, Inhye E. Ahn, Andy Itsara, Susan Soto, Pia Nierman, Sivasubramanian Baskar, Lita A. Freeman, Xin Tian, Pamela L. Tuma, Chingiz Underbayev, Erika M. Gaglione, Jonathan Chen, Anfal Alsadhan
Supplementary Table S6. DEGs for Baseline Comparison of CD49d+ and CD49d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150312c98f7abce27ddb7701ba534bab
https://doi.org/10.1158/1078-0432.23183837
https://doi.org/10.1158/1078-0432.23183837
Autor:
Adrian Wiestner, Maissa Mhibik, Tanja Nicole Hartmann, Elena Bibikova, Clare Sun, Inhye E. Ahn, Andy Itsara, Susan Soto, Pia Nierman, Sivasubramanian Baskar, Lita A. Freeman, Xin Tian, Pamela L. Tuma, Chingiz Underbayev, Erika M. Gaglione, Jonathan Chen, Anfal Alsadhan
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9a64b4b25861d78576cc389c3aec03
https://doi.org/10.1158/1078-0432.23183858.v1
https://doi.org/10.1158/1078-0432.23183858.v1
Autor:
Adrian Wiestner, Maissa Mhibik, Tanja Nicole Hartmann, Elena Bibikova, Clare Sun, Inhye E. Ahn, Andy Itsara, Susan Soto, Pia Nierman, Sivasubramanian Baskar, Lita A. Freeman, Xin Tian, Pamela L. Tuma, Chingiz Underbayev, Erika M. Gaglione, Jonathan Chen, Anfal Alsadhan
Purpose:To determine the role of CD49d for response to Bruton's tyrosine kinase inhibitors (BTKi) in patients with chronic lymphocytic leukemia (CLL).Patients and Methods:In patients treated with acalabrutinib (n = 48), CD49d expression, VLA-4 integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedb5e7d5092d8beaf29db3e171f1b4a
https://doi.org/10.1158/1078-0432.c.6664574.v1
https://doi.org/10.1158/1078-0432.c.6664574.v1
Autor:
Maissa Mhibik, Erika M Gaglione, David Eik, John Herrick, Janet Le, Inhye E Ahn, Christopher Chiu, Monica Wielgos-Bonvallet, Ida H Hiemstra, Esther CW Breij, Jenny Chen, Edward B Reilly, Pearlie K. Epling-Burnette, Edith Szafer Glusman, Clare Sun, Adrian Wiestner
Publikováno v:
Blood Advances.
Chronic lymphocytic leukemia (CLL) is an immunosuppressive disease characterized by increased infectious morbidity and inferior anti-tumor activity of immunotherapies. Targeted therapy with Bruton's tyrosine kinase inhibitors (BTKis), or the Bcl-2 in
Autor:
Louis M. Staudt, Adrian Wiestner, Wyndham H. Wilson, Erika M. Gaglione, Clare Sun, Inhye E. Ahn, Michael C. Kelly, Zachary Rae, Thomas Oellerich, Björn Häupl, Craig J. Thomas, Carleen Klumpp-Thomas, Crystal McKnight, Lu Chen, Kelli M. Wilson, Xiaohu Zhang, Michele Ceribelli, Sandrine Roulland, Weihong Xu, Xin Yu, Hong Zhao, Yandan Yang, Daniel E. Webster, Ryan M. Young, Jaewoo Choi, Monica Kasbekar, George W. Wright, DaWei Huang, James Q. Wang, James D. Phelan, Arthur L. Shaffer
Supplemental Table 7. Targeting epigenetic resistance to BTK inhibitor treatment in ABC DLBCL, relates to Fig7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2652d2707a75749f0f8329179db6090c
https://doi.org/10.1158/2643-3230.22543767.v1
https://doi.org/10.1158/2643-3230.22543767.v1
Autor:
Louis M. Staudt, Adrian Wiestner, Wyndham H. Wilson, Erika M. Gaglione, Clare Sun, Inhye E. Ahn, Michael C. Kelly, Zachary Rae, Thomas Oellerich, Björn Häupl, Craig J. Thomas, Carleen Klumpp-Thomas, Crystal McKnight, Lu Chen, Kelli M. Wilson, Xiaohu Zhang, Michele Ceribelli, Sandrine Roulland, Weihong Xu, Xin Yu, Hong Zhao, Yandan Yang, Daniel E. Webster, Ryan M. Young, Jaewoo Choi, Monica Kasbekar, George W. Wright, DaWei Huang, James Q. Wang, James D. Phelan, Arthur L. Shaffer
Supplemental Table 1. Epigenetic Ibrutinib Resistance in ABC DLBCL lines, , relates to Fig. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578b737ff90e1bb7d4f9cf9a43f9971c
https://doi.org/10.1158/2643-3230.22543788.v1
https://doi.org/10.1158/2643-3230.22543788.v1
Autor:
Louis M. Staudt, Adrian Wiestner, Wyndham H. Wilson, Erika M. Gaglione, Clare Sun, Inhye E. Ahn, Michael C. Kelly, Zachary Rae, Thomas Oellerich, Björn Häupl, Craig J. Thomas, Carleen Klumpp-Thomas, Crystal McKnight, Lu Chen, Kelli M. Wilson, Xiaohu Zhang, Michele Ceribelli, Sandrine Roulland, Weihong Xu, Xin Yu, Hong Zhao, Yandan Yang, Daniel E. Webster, Ryan M. Young, Jaewoo Choi, Monica Kasbekar, George W. Wright, DaWei Huang, James Q. Wang, James D. Phelan, Arthur L. Shaffer
Supplemental Table 6. RAC2 protein interactions are a marker of epigenetic ibrutinib resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f181db2bea5807c198b955fb708ff5
https://doi.org/10.1158/2643-3230.22543770.v1
https://doi.org/10.1158/2643-3230.22543770.v1