Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Erika L. Pearson"'
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 108031- (2020)
Externí odkaz:
https://doaj.org/article/a8dcec38d7984bd082b3ebf90ca76fa7
Autor:
Ryan J. McGinty, Franco Puleo, Anna Y. Aksenova, Julia A. Hisey, Alexander A. Shishkin, Erika L. Pearson, Eric T. Wang, David E. Housman, Claire Moore, Sergei M. Mirkin
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2490-2500 (2017)
Expansions of microsatellite repeats are responsible for numerous hereditary diseases in humans, including myotonic dystrophy and Friedreich’s ataxia. Whereas the length of an expandable repeat is the main factor determining disease inheritance, re
Externí odkaz:
https://doaj.org/article/0dfcf17ded7242c7a59c4d6e7f1ea13e
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1919-1933.e5 (2019)
Summary: The yeast protein Ipa1 was recently discovered to interact with the Ysh1 endonuclease of the pre-mRNA cleavage and polyadenylation (C/P) machinery, and Ipa1 mutation impairs 3′end processing. We report that Ipa1 globally promotes proper tr
Externí odkaz:
https://doaj.org/article/cdbdb6896941481894b3a4b44637f022
Autor:
Franco Puleo, Anna Y. Aksenova, Claire Moore, Julia A. Hisey, David E. Housman, Sergei M. Mirkin, Erika L. Pearson, Ryan J. McGinty, Eric T. Wang, Alexander A. Shishkin
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2490-2500 (2017)
Expansions of microsatellite repeats are responsible for numerous hereditary diseases in humans, including myotonic dystrophy and Friedreich’s ataxia. While the length of an expandable repeat is the main factor determining disease inheritance, rece
Publikováno v:
Nature Reviews Molecular Cell Biology. 12:283-294
The pervasiveness of RNA synthesis in eukaryotes is largely the result of RNA polymerase II (Pol II)-mediated transcription, and termination of its activity is necessary to partition the genome and maintain the proper expression of neighbouring genes
Autor:
Erika L. Pearson, Claire Moore
Publikováno v:
Cell Reports, Vol 9, Iss 3, Pp 821-828 (2014)
SummaryCurrent models of transcription termination factor recruitment to the RNA polymerase II (Pol II) transcription complex rely exclusively on the direct interaction between the termination factor and phosphorylated isoforms of the Pol II C-termin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9413754ca9de822a409fd913222c1ed
https://europepmc.org/articles/PMC4250834/
https://europepmc.org/articles/PMC4250834/
Autor:
Claire Moore, Erika L. Pearson
Publikováno v:
The Journal of biological chemistry. 288(27)
Proper RNA polymerase II (Pol II) transcription termination is essential to generate stable transcripts, to prevent interference at downstream loci, and to recycle Pol II back to the promoter (1-3). As such, termination is an intricately controlled p