Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Erika J Martin"'
Autor:
Loren K Liebrecht, Jason Newton, Erika J Martin, Niluka Wickramaratne, Sudha Jayaraman, Jinfeng Han, Michel Aboutanos, Donald F Brophy, Martin J Mangino
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215386 (2019)
BackgroundNovel crystalloid solutions containing polyethylene glycol polymers (PEG-20k) produce dramatic resuscitation effects but dose-dependently produce a hypocoagulative state. The objective of this study was to examine possible mechanisms of thi
Externí odkaz:
https://doaj.org/article/d46ba5f0791a4a3fb01818c58131aedf
Thromboelastographic analysis of novel polyethylene glycol based low volume resuscitation solutions.
Autor:
Loren K Liebrecht, Jason Newton, Erika J Martin, Nina Wickramaratne, Sudha Jayaraman, Jinfeng Han, Michel Aboutanos, Donald F Brophy, Martin J Mangino
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207147 (2018)
BACKGROUND:Low volume resuscitation (LVR) in shock prevents deleterious effects of crystalloid loading in pre-hospital settings. Polyethylene glycol 20,000 (PEG-20k) based LVR solutions are 20-fold more effective at maintaining perfusion and survival
Externí odkaz:
https://doaj.org/article/b8b19a79d9844ec38c7a121104121563
Autor:
J. Vincent Edwards, Nicolette T. Prevost, Doug J. Hinchliffe, Sunghyun Nam, SeChin Chang, Rebecca J. Hron, Crista A. Madison, Jade N. Smith, Chelsie N. Poffenberger, Michelle M. Taylor, Erika J. Martin, Kirsty J. Dixon
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17115 (2023)
The need for prehospital hemostatic dressings that exert an antibacterial effect is of interest for prolonged field care. Here, we consider a series of antibacterial and zeolite formulary treatment approaches applied to a cotton-based dressing. The d
Externí odkaz:
https://doaj.org/article/f66667ddc6b04423a851f27a810771af
Platelet and White Cell Reactivity to Top-Load Intravenous Perfluorocarbon Infusion in Healthy Sheep
Publikováno v:
Journal of Surgical Research. 267:342-349
Perfluorocarbon emulsions (PFCs) are intravenous artificial oxygen carriers with enhanced gas solubility. As lipid micelle nanoparticle emulsions, PFCs may have a class effect that causes degrees of thrombocytopenia. Understanding the extent of the p
Autor:
Kaushik Das, Usha R. Pendurthi, Marylyn Manco‐Johnson, Erika J. Martin, Donald F. Brophy, L. Vijaya Mohan Rao
Publikováno v:
Journal of thrombosis and haemostasis : JTHREFERENCES. 20(8)
Autor:
Donald F. Brophy, Rami A. Al-Horani, Masahiro Sakagami, Elsamani I. Abdelfadiel, Erika J. Martin, Daniel K. Afosah, Bassem M. Mohammed, Shravan Morla, Umesh R. Desai, Jyothi C. Sistla
Publikováno v:
J Thromb Haemost
Background Human factor XIa (FXIa) is an actively pursued target for development of safer anticoagulants. Our long-standing hypothesis has been that allosterism originating from heparin-binding site(s) on coagulation enzymes is a promising approach t
Autor:
Chau Vo, Todd Stravitz, Luis A. Guzman, Donald F. Brophy, Mohammad S. Siddiqui, Cory R. Trankle, Erika J. Martin, Laura Puckett
Publikováno v:
JACC: Cardiovascular Interventions. 13:661-663
Decompensated cirrhosis is associated with high morbidity and mortality in the absence of liver transplantation (LT) [(1)][1]. LT is a high-risk surgery, and all potential LT waitlist registrants undergo extensive workup to assess and optimize their
Autor:
Donald F. Brophy, John E. Murphy, Debra D. Pittman, Bassem M. Mohammed, John C. Barrett, Janice Kuhn, Swapnil Rakhe, Pengling Sun, Erika J. Martin, Sunita Patel-Hett, Melinda E Nolte
Publikováno v:
Haemophilia. 25:797-806
Introduction Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of the extrinsic pathway that negatively regulates thrombin production during coagulation. Under haemophilic conditions, where the intrinsic coagulation pathway is impaire
Publikováno v:
Haemophilia : the official journal of the World Federation of HemophiliaREFERENCES. 27(4)
Introduction Tissue factor pathway inhibitor (TFPI) is an endogenous protein that inhibits the extrinsic (tissue factor) pathway and negatively regulates thrombin production during coagulation. Inhibiting TFPI may become a useful target for haemophil
Autor:
Erika J. Martin, Melinda E Nolte, Bassem M. Mohammed, Marisa Ninivaggi, John C. Barrett, Emily K. Waters, Janice Kuhn, Donald F. Brophy, Mirella Ezban
Publikováno v:
Haemophilia. 24:815-822
INTRODUCTION The thrombin generation assay (TGA) can be used to monitor factor replacement therapy in patients with haemophilia. The TGA assay is typically performed using tissue factor as the reaction activator; however, activating with FIXa or FXIa