Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Erika Huijser"'
Autor:
P. Martijn Kolijn, Erika Huijser, M. Javad Wahadat, Cornelia G. van Helden-Meeuwsen, Paul L. A. van Daele, Zana Brkic, Jos Rijntjes, Konnie M. Hebeda, Patricia J. T. A. Groenen, Marjan A. Versnel, Rogier M. Thurlings, Anton W. Langerak
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionActivated B cells play a key role in the pathogenesis of primary Sjögren’s syndrome (pSS) through the production of autoantibodies and the development of ectopic germinal centers in the salivary glands and other affected sites. Around
Externí odkaz:
https://doaj.org/article/f8ad4e01c67f479783c7d60574855f40
Autor:
Sylvia Kamphuis, Marjan A Versnel, Marleen Verkaaik, Wahadat M Javad, Hongchao Qi, Cornelia G van Helden-Meeuwsen, Erika Huijser, Lotte van den Berg, Jens Göpfert, Marco Schreurs
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 2 (2022)
Externí odkaz:
https://doaj.org/article/498d76bcd75e4fa2af8543cd187f9acb
Autor:
Erika Huijser, Cornelia G. van Helden-Meeuwsen, Dwin G. B. Grashof, Jessica R. Tarn, Zana Brkic, Josje M. A. Huisman, M. Javad Wahadat, Harmen J. G. van de Werken, Ana P. Lopes, Joel A. G. van Roon, Paul L. A. van Daele, Sylvia Kamphuis, Wan-Fai Ng, Siroon Bekkering, Leo A. B. Joosten, Willem A. Dik, Marjan A. Versnel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundTrained immunity – or innate immune memory – can be described as the long-term reprogramming of innate immune cells towards a hyperresponsive state which involves intracellular metabolic changes. Trained immunity has been linked to athe
Externí odkaz:
https://doaj.org/article/72f7b5e73ccf4457a9a39a2512306f2e
Genetic Variants of the BAFF Gene and Risk of Fatigue Among Patients With Primary Sjögren’s Syndrome
Autor:
Christina-Maria Flessa, Evangelia Zampeli, Maria-Eleftheria Evangelopoulos, Vasilis Natsis, Iris L. A. Bodewes, Erika Huijser, Marjan A. Versnel, Haralampos M. Moutsopoulos, Clio P. Mavragani
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Background/PurposePrimary Sjögren’s Syndrome (SS) is characterized by B lymphocyte hyperactivity with B cell activating factor (BAFF) acting as an important regulator. Single Nucleotide Polymorphisms (SNPs) of the BAFF gene have been implicated in
Externí odkaz:
https://doaj.org/article/15fb7d63c5604ccfbb1fe214b2e21159
Autor:
Benjamin Schrijver, Douwe J Dijkstra, Nicole V Borggreven, Rina La Distia Nora, Erika Huijser, Marjan A Versnel, P Martin vanHagen, Simone A Joosten, Leendert A Trouw, Willem A Dik
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 10, Pp n/a-n/a (2020)
Abstract Objectives To examine the relation between serum C1q levels and blood type‐1 interferon signature (type‐1 IFN signature) in active pulmonary tuberculosis (APTB) and to determine whether combined measurement of serum C1q and type‐1 IFN
Externí odkaz:
https://doaj.org/article/8244c9ee1f094ba2a70b6d5de909fac5
Autor:
Benjamin Schrijver, Thomas Mandl, Paul L A van Daele, Peter Olsson, Jens C. Göpfert, Cornelia G van Helden-Meeuwsen, Zana Brkic, Willem A. Dik, Marco W.J. Schreurs, Sanne Jansen, Marjan A. Versnel, Erika Huijser
Publikováno v:
Rheumatology (United Kingdom), 61(5), 2156-2166. Oxford University Press
Objectives Type I IFN (IFN-I) activation is a prominent feature of primary SS (pSS), SLE and SSc. Ultrasensitive single-molecule array (Simoa) technology has facilitated the measurement of subfemtomolar concentrations of IFNs. Here we aimed to measur
Autor:
Erika Huijser, Iris L A Bodewes, Mirthe S Lourens, Cornelia G van Helden-Meeuwsen, Thierry P P van den Bosch, Dwin G B Grashof, Harmen J G van de Werken, Ana P Lopes, Joel A G van Roon, Paul L A van Daele, Zana Brkic, Willem A Dik, Marjan A Versnel
Publikováno v:
Rheumatology (Oxford, England), 61(8), 3491-3496. Oxford University Press
Objectives Cytosolic DNA-sensing pathway stimulation prompts type I IFN (IFN-I) production, but its role in systemic IFN-I pathway activation in primary SS (pSS) is poorly studied. Here we investigate the responsiveness of pSS monocytes and plasmacyt
Autor:
M Javad Wahadat, Hongchao Qi, Cornelia G van Helden-Meeuwsen, Erika Huijser, Lotte van den Berg, Annette van Dijk-Hummelman, Jens C Göpfert, Anne Heine, Marleen Verkaaik, Marco W J Schreurs, Willem A Dik, Sylvia Kamphuis, Marjan A Versnel
Publikováno v:
Rheumatology. Oxford University Press
Objective To study the association of serum IFNα2 levels measured by ultrasensitive single-molecule array (Simoa) and the IFN-I gene signature (IGS) with disease activity and determine whether these assays can mark disease activity states in a longi
Autor:
Marleen Verkaaik, Wahadat M Javad, Hongchao Qi, Cornelia G van Helden-Meeuwsen, Erika Huijser, Lotte van den Berg, Jens Göpfert, Marco Schreurs, Sylvia Kamphuis, Marjan A Versnel
Publikováno v:
Thursday 06 October 2022 from 13:00 to 14:10.
Autor:
Erika Huijser, Marjan A. Versnel
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 532, p 532 (2021)
Journal of Clinical Medicine
Journal of Clinical Medicine, 10(3):532, 1-20. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Clinical Medicine
Journal of Clinical Medicine, 10(3):532, 1-20. Multidisciplinary Digital Publishing Institute (MDPI)
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease characterized by dryness of the eyes and mucous membranes, which can be accompanied by various extraglandular autoimmune manifestations. The majority of patients exhibit p