Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Erika Hemmerová"'
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1214 (2020)
Progressive mitochondrial dysfunction due to the accumulation of amyloid beta (Aβ) peptide within the mitochondrial matrix represents one of the key characteristics of Alzheimer’s disease (AD) and appears already in its early stages. Inside the mi
Externí odkaz:
https://doaj.org/article/7e142d969a4f4ffe8d3d2771f5c6854d
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 9727, p 9727 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 9727, p 9727 (2020)
In early stages of Alzheimer’s disease (AD), amyloid beta (Aβ) accumulates in the mitochondrial matrix and interacts with mitochondrial proteins, such as cyclophilin D (cypD) and 17β-hydroxysteroid dehydrogenase 10 (17β-HSD10). Multiple processe
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
In early stages of Alzheimer’s disease (AD), amyloid-β (Aβ) accumulates in neuronal mitochondria where it interacts with a number of biomolecules including 17beta-hydroxysteroide dehydrogenase 10 (17β-HSD10) and cyclophilin D (cypD). It has been
Publikováno v:
Applied Surface Science. 546:148984
Functional materials employing organic coatings on inorganic substrates are perceived as potential platforms for applications in a variety of fields. Therefore, the investigation of interactions of such systems with the microenvironment has become an
Autor:
Erika Hemmerová, Zdenka Kristofikova, Giusy Finocchiaro, Tomáš Špringer, Jiří Homola, Martin Vyhnalek
Publikováno v:
Sensors and Actuators B: Chemical. 316:128146
The development of methods advancing the understanding of molecular processes related to Alzheimer’s disease (AD) and detection of biomarkers of AD presents an important research goal. We present a new biosensor-based method for the detection of a