Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Erika Hähnel"'
Publikováno v:
The Breast. 3:141-146
GCDFP-15/PIP expression in the breast is regulated by a variety of hormones and is a marker of apocrine differentiation. GCDFP-15/PIP expression in malignant and surrounding non-neoplastic breast tissue was assessed using both Northern blotting and i
Publikováno v:
International Journal of Cancer. 58:157-160
Biological functions proposed for the ST3 and nm23 genes in tumour development and progression seem to be directly opposed. Stromelysin-3 (ST3) is a putative member of the matrix metalloproteinase family. ST3 has been implicated in the progression of
Autor:
John Papadimitriou, Peter Robbins, Hugh Dawkins, Erika Hähnel, Jenett M. Harvey, Rebecca J. Goodall, Mohinder Sarna, Roland Hähnel, Gregory F. Sterrett
Publikováno v:
Pathology. 26:423-428
Expression levels of nm23-H1 were evaluated in a variety of normal benign and malignant breast tissues by Northern and slot blot. Tissues from 153 patients presenting with palpable breast lesions were studied: 132 primary infiltrating breast cancers,
Publikováno v:
Pathobiology. 62:82-89
Expression of the hormone-regulated genes, pS2, prolactin-inducible protein (PIP) and fatty acid synthetase (FAS), was investigated by Northern blotting in primary breast carcinoma, metastatic breast cancer in axillary lymph nodes, in uninvolved brea
Autor:
Erika Hähnel, Mohinder Sarna, Peter Robbins, Greg Sterrett, R.J. Goodall, N H de Klerk, Hugh Dawkins, Jennet Harvey, John Papadimitriou, Roland Hähnel
Publikováno v:
The Breast. 2:239-245
The nm23 -H1 gene has tumour suppressor functions and is a putative metastasis suppressor. Higher levels of expression of the gene in breast carcinoma have been associated with the absence of lymph node metastasis, and with longer relapse free interv
Autor:
Roland Hähnel, Gregory F. Sterrett, Erika Hähnel, Peter Robbins, Jennet Harvey, Raymond Joyce
Publikováno v:
International Journal of Cancer. 55:771-774
Stromelysin-3 expression was studied by Northern blotting in 222 tissue samples including primary and metastatic breast carcinoma and normal breast tissue. Uninvolved breast tissue from mastectomy specimens, normal breast tissue from reduction mammop
Publikováno v:
Pathology. 25:255-260
pS2 expression was studied in a series of 82 primary breast carcinomas using and comparing a radioimmunoassay (RIA) technique and immunohistochemistry (IPOX). There was close correlation of the results obtained with each technique. Accurate and relia
Publikováno v:
Breast Cancer Research and Treatment. 24:71-74
The expression of the pS2 gene in breast tissues was assessed by measuring pS2-protein using a radioimmunoassay, and by determining pS2-mRNA using Northern blotting. There was a good correlation between the two measurements, indicating that expressio
Publikováno v:
Breast cancer research and treatment. 28(3)
pS2 expression in normal breast tissue removed for cosmetic reasons was significantly lower than in uninvolved breast tissues from mastectomies for breast carcinomas. It is speculated that the presence of the carcinoma, or factors related to its deve
Publikováno v:
Breast cancer research and treatment. 20(3)
pS2 mRNA was estimated in uninvolved breast tissue and breast carcinoma from the same patients. pS2 mRNA was clearly detected in 14 of 59 uninvolved breast tissues and in 30 of 58 breast carcinomas. pS2 mRNA was found more frequently in uninvolved br