Výsledky vyhledávání - "Erika Girardi"

Akademický článek

DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection

Autor: Mélanie Messmer, Louison Pierson, Charline Pasquier, Nikola Djordjevic, Johana Chicher, Philippe Hammann, Sébastien Pfeffer, Erika Girardi

Publikováno v: Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)

Abstract Background RNA helicases are emerging as key factors regulating host-virus interactions. The DEAD-box ATP-dependent RNA helicase DDX5, which plays an important role in many aspects of cellular RNA biology, was also found to either promote or

Externí odkaz: https://doaj.org/article/f30e94f5d5ec4701b25198871077b914

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Akademický článek

Human DICER helicase domain recruits PKR and modulates its antiviral activity.

Autor: Thomas C Montavon, Morgane Baldaccini, Mathieu Lefèvre, Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Philippe Hammann, Johana Chicher, Sébastien Pfeffer

Publikováno v: PLoS Pathogens, Vol 17, Iss 5, p e1009549 (2021)

The antiviral innate immune response mainly involves type I interferon (IFN) in mammalian cells. The contribution of the RNA silencing machinery remains to be established, but several recent studies indicate that the ribonuclease DICER can generate v

Externí odkaz: https://doaj.org/article/40b382e1a8574c88a204a648527086ec

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Akademický článek

Genome-Wide CRISPR-Cas9 Screen Reveals the Importance of the Heparan Sulfate Pathway and the Conserved Oligomeric Golgi Complex for Synthetic Double-Stranded RNA Uptake and Sindbis Virus Infection

Autor: Olivier Petitjean, Erika Girardi, Richard Patryk Ngondo, Vladimir Lupashin, Sébastien Pfeffer

Publikováno v: mSphere, Vol 5, Iss 6 (2020)

ABSTRACT Double-stranded RNA (dsRNA) is the hallmark of many viral infections. dsRNA is produced either by RNA viruses during replication or by DNA viruses upon convergent transcription. Synthetic dsRNA is also able to mimic viral-induced activation

Externí odkaz: https://doaj.org/article/ce2e1b6b2c6d4e95b2cdb7888fed112e

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Akademický článek

On the Importance of Host MicroRNAs During Viral Infection

Autor: Erika Girardi, Paula López, Sébastien Pfeffer

Publikováno v: Frontiers in Genetics, Vol 9 (2018)

Every living organism has to constantly face threats from the environment and deal with a large number of pathogens against which it has to defend itself to survive. Among those, viruses represent a large class of obligatory intracellular parasites,

Externí odkaz: https://doaj.org/article/f9dde1f099844a0284a371f774efb8f5

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Akademický článek

Identification of RNase L-Dependent, 3′-End-Modified, Viral Small RNAs in Sindbis Virus-Infected Mammalian Cells

Autor: Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Pasi Kaukinen, Sébastien Pfeffer

Publikováno v: mBio, Vol 4, Iss 6 (2013)

ABSTRACT Small RNAs play a critical role in host-pathogen interaction. Indeed, small RNA-mediated silencing or RNA interference (RNAi) is one of the earliest forms of antiviral immunity. Although it represents the main defense system against viruses

Externí odkaz: https://doaj.org/article/e6b1ce8553864c5da1f666e2f8bf580b

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CD169 + macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

Autor: Abdouramane Camara, Alice C. Lavanant, Jun Abe, Henri Lee Desforges, Yannick O. Alexandre, Erika Girardi, Zinaida Igamberdieva, Kenichi Asano, Masato Tanaka, Thomas Hehlgans, Klaus Pfeffer, Sébastien Pfeffer, Scott N. Mueller, Jens V. Stein, Christopher G. Mueller

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance The CD169+ macrophages that play an important role in the fight against infections and cancer are receptive to environmental signals for their differentiation. We show that lymph node and splenic CD169+ macrophages require both LTβR and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6172aaf279de6038ce72fa8abed23989
http://www.pnas.org/lookup/doi/10.1073/pnas.2108540119

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Human DICER helicase domain recruits PKR and modulates its antiviral activity

Autor: Philippe Hammann, Sébastien Pfeffer, Mathieu Lefèvre, Erika Girardi, Johana Chicher, Morgane Baldaccini, Mélanie Messmer, Thomas Montavon, Béatrice Chane-Woon-Ming

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2021, 17 (5), pp.e1009549. ⟨10.1371/journal.ppat.1009549⟩
PLOS Pathogens
bioRxiv
PLoS Pathogens, 2021, 17 (5), pp.e1009549. ⟨10.1371/journal.ppat.1009549⟩
PLoS Pathogens, Vol 17, Iss 5, p e1009549 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85ba227846bf60188097ab170be8f08
https://hal.archives-ouvertes.fr/hal-03328063/document

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