Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Erika D. Eggers"'
Autor:
Erika D. Eggers
Publikováno v:
Annual Review of Vision Science. 9
Although diabetic retinopathy (DR) is clinically diagnosed as a vascular disease, many studies find retinal neuronal and visual dysfunction before the onset of vascular DR. This suggests that DR should be viewed as a neurovascular disease. Prior to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14059bddcf64de9e4727228b0254e7ef
https://doi.org/10.1146/annurev-vision-111022-123810
https://doi.org/10.1146/annurev-vision-111022-123810
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The balance of neuronal excitation and inhibition is important for proper retinal signaling. A previous report showed that diabetes selectively reduces light-evoked inhibition to the retinal dim light rod pathway, changing this balance. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244e90b89b4453d43926eede7a1b0ee3
http://europepmc.org/articles/PMC6779064
http://europepmc.org/articles/PMC6779064
Purpose: It has been known for some time that normal retinal signaling is disrupted early on in diabetes, before the onset of the vascular pathologies associated with diabetic retinopathy. There is growing evidence that levels of retinal dopamine, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652db43451c670ede962aa12c6674146
https://doi.org/10.1101/2020.10.31.363564
https://doi.org/10.1101/2020.10.31.363564
Autor:
Michael D. Flood, Erika D. Eggers
Publikováno v:
J Neurophysiol
The adaptation of ganglion cells to increasing light levels is a crucial property of the retina. The retina must respond to light intensities that vary by 10-12 orders of magnitude, but the dynamic range of ganglion cell responses covers only ∼3 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea3fe79af341a874f661a001d02257d
https://doi.org/10.1101/2020.10.29.361147
https://doi.org/10.1101/2020.10.29.361147
Publikováno v:
Exp Eye Res
Retinal signaling under dark-adapted conditions is perturbed during early diabetes. Additionally, dopamine, the main neuromodulator of retinal light adaptation, is diminished in diabetic retinas. However, it is not known if this dopamine deficiency c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9b57e56a299a08afcae65945d0a726
https://pubmed.ncbi.nlm.nih.gov/32910942
https://pubmed.ncbi.nlm.nih.gov/32910942
Autor:
Erika D. Eggers, Reece Mazade
Publikováno v:
Vis Neurosci
During adaptation to an increase in environmental luminance, retinal signaling adjustments are mediated by the neuromodulator dopamine. Retinal dopamine is released with light and can affect center-surround receptive fields, the coupling state betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e556924c76a80db5adf7b1525adce8b5
https://pubmed.ncbi.nlm.nih.gov/32046810
https://pubmed.ncbi.nlm.nih.gov/32046810
Autor:
Teresia A Carreon, Erika D. Eggers
Publikováno v:
Vis Neurosci
Diabetic retinopathy is now well understood as a neurovascular disease. Significant deficits early in diabetes are found in the inner retina that consists of bipolar cells that receive inputs from rod and cone photoreceptors, ganglion cells that rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4ab0b3a7a51531f39945d2de0deaa7
https://doi.org/10.1017/s095252382000005x
https://doi.org/10.1017/s095252382000005x
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Retinal neuronal signaling is disrupted early in diabetes, before the onset of the vascular pathologies associated with diabetic retinopathy. There is also growing evidence that retinal dopamine, a neuromodulator that mediates light adaptatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516da3699dc32e539cc840be09a789fc
https://doi.org/10.1167/iovs.63.1.33
https://doi.org/10.1167/iovs.63.1.33
Publikováno v:
Journal of Neurophysiology. 120:867-879
Dopamine modulation of retinal signaling has been shown to be an important part of retinal adaptation to increased background light levels, but the role of dopamine modulation of retinal inhibition is not clear. We previously showed that light adapta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae808db595967bd08f8de7dae593d46
https://doi.org/10.1152/jn.00855.2017
https://doi.org/10.1152/jn.00855.2017
Publikováno v:
Journal of neurophysiology. 121(4)
During adaptation from dim to bright environments, changes in retinal signaling are mediated, in part, by dopamine. Dopamine is released with light and can modulate retinal receptive fields, neuronal coupling, inhibitory receptors, and rod pathway in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d2c0b81b7af5c178816293b69e2c6e
https://pubmed.ncbi.nlm.nih.gov/30726156
https://pubmed.ncbi.nlm.nih.gov/30726156