Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Erika Bourguet"'
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100612- (2022)
Cyclization of judiciously substituted N-aminoindole species provides a convenient synthetic route to ABE building block types I and II as tricyclic skeleton commonly found in the motif of indolic alkaloids. The approach consists in obtaining a tricy
Externí odkaz:
https://doaj.org/article/56aaa8d087e64353830bb018d53a9274
Publikováno v:
Journal of Medicinal Chemistry. 65:3002-3025
This Perspective describes the classification, structures, substrates, mechanisms of action, and implications of human neuraminidases (hNEUs) in various pathologies. Some inhibitors have been developed for each isoform, leading to more precise intera
Publikováno v:
Current medicinal chemistry. 28(42)
This review summarizes key literature defining the phenotypes of individual class IIa HDAC proteins and compounds that selectively target their enzymatic catalytic domain (CD). The focus is on the effects of class IIa HDACs in physiological and patho
Autor:
Erika Bourguet, Mickaël Naassila
Publikováno v:
Future Medicinal Chemistry
Future Medicinal Chemistry, Future Science, 2019, 11 (11), pp.1241-1243. ⟨10.4155/fmc-2019-0036⟩
Future Medicinal Chemistry, Future Science, 2019, 11 (11), pp.1241-1243. ⟨10.4155/fmc-2019-0036⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85663ad934046f3dec4a24cc6c128b99
https://hal.archives-ouvertes.fr/hal-02429347
https://hal.archives-ouvertes.fr/hal-02429347
Autor:
Anne-Pascaline Martin, Janos Sapi, Isabelle Villena, Sylvie Brassart-Pasco, Kristina Brazhnik, Igor Nabiev, Gautier Moroy, Alyona Sukhanova, Georges Bellon, Erika Bourguet
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2016, 27 (4), pp.1067-1081. ⟨10.1021/acs.bioconjchem.6b00065⟩
Bioconjugate Chemistry, American Chemical Society, 2016, 27 (4), pp.1067-1081. ⟨10.1021/acs.bioconjchem.6b00065⟩
International audience; The development of chemically designed matrix metalloprotease (MMP) inhibitors has advanced the understanding of the roles of MMPs in different diseases. Most MMP probes designed are fluorogenic substrates, often suffering fro
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2018, 61 (5), pp.1745-1766. ⟨10.1021/acs.jmedchem.7b00115⟩
Journal of Medicinal Chemistry, American Chemical Society, 2018, 61 (5), pp.1745-1766. ⟨10.1021/acs.jmedchem.7b00115⟩
International audience; Alcohol use disorder (AUD) represents a serious public health issue, and discovery of new therapies is a pressing necessity. Alcohol exposure has been widely demonstrated to modulate epigenetic mechanisms, such as histone acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafe68c515386709db49a08f90101a99
https://hal.archives-ouvertes.fr/hal-01929517
https://hal.archives-ouvertes.fr/hal-01929517
Autor:
Aurélie Trussardi-Régnier, Diana Sketriené, Erika Bourguet, Rémi Legastelois, Gautier Moroy, Céline Gonzalez, Jérôme Jeanblanc, Mathieu Létévé, Mickaël Naassila
Publikováno v:
Psychopharmacology
Psychopharmacology, Springer Verlag, 2018, 235 (6), pp.1835-1844. ⟨10.1007/s00213-018-4917-5⟩
Psychopharmacology, Springer Verlag, 2018, 235 (6), pp.1835-1844. ⟨10.1007/s00213-018-4917-5⟩
International audience; RationaleRecent preclinical research suggested that histone deacetylase inhibitors (HDACIs) and specifically class I HDAC selective inhibitors might be useful to treat alcohol use disorders (AUDs).ObjectiveThe objective of thi
Publikováno v:
Biologie aujourd'hui. 211(1)
Alcohol use disorder is a devastating illness with a profound health impact, and its development is dependent on both genetic and environmental factors. This disease occurs over time and requires changes in brain gene expression. There is converging
Publikováno v:
Biologie Aujourd'hui
Biologie Aujourd'hui, EDP sciences, 2017, 211 (1), pp.83-91. ⟨10.1051/jbio/2017014⟩
Biologie Aujourd'hui, EDP sciences, 2017, 211 (1), pp.83-91. ⟨10.1051/jbio/2017014⟩
International audience; Alcohol use disorder is a devastating illness with a profound health impact, and its development is dependent on both genetic and environmental factors. This disease occurs over time and requires changes in brain gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9e05af3c1e164ec6e1c4be8b965685
https://hal.archives-ouvertes.fr/hal-01929543
https://hal.archives-ouvertes.fr/hal-01929543
Publikováno v:
Scopus-Elsevier
Anti-Cancer Agents in Medicinal Chemistry
Anti-Cancer Agents in Medicinal Chemistry, Bentham Science Publishers, 2012, 12 (6), pp.565-579
Anti-Cancer Agents in Medicinal Chemistry
Anti-Cancer Agents in Medicinal Chemistry, Bentham Science Publishers, 2012, 12 (6), pp.565-579
Human neutrophil elastase (HNE), a main actor in the development of chronic obstructive pulmonary diseases, has been recently involved in non-small cell lung cancer progression. It can act at several levels (i) intracellularly, cleaving for instance