Výsledky vyhledávání - "Erika A. Scholl"

Irradiance and Temperature Control Chamber for Testing Solar Cell Performance

Publikováno v: 2021 IEEE 48th Photovoltaic Specialists Conference (PVSC).

This report describes the design, construction, and validation of an irradiance and temperature control chamber used to measure temperature-dependent current voltage characteristics of photovoltaic (PV) solar cells under varying conditions in order t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43f90a8e94c694024ab590e3a66f2afa
https://doi.org/10.1109/pvsc43889.2021.9518734

Zobrazit plný text záznamu

Vanishing White Matter Disease Expression of Truncated EIF2B5 Activates Induced Stress Response

Autor: Edward W. Hsu, Matthew D. Keefe, Erika A. Scholl, Joshua L. Bonkowsky, Samuel Colby, Samer S. Merchant, Tamara J. Stevenson, D. M. Bowles, Kathryn A Glaittli, Hung-Yu Shih, Haille E Soderholm

Publikováno v: eLife, Vol 9 (2020)
eLife

Vanishing White Matter disease (VWM) is a severe leukodystrophy of the central nervous system caused by mutations in subunits of the eukaryotic initiation factor 2B complex (eIF2B). Current models only partially recapitulate key disease features, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0503061717502e5bc0e530df3898a8

Zobrazit plný text záznamu

Age-dependent behaviors, seizure severity and neuronal damage in response to nerve agents or the organophosphate DFP in immature and adult rats

Autor: Jeffrey J. Ekstrand, Steven L. Bealer, Stephanie M. Miller-Smith, Mark J. Lehmkuhle, John H. McDonough, F. Edward Dudek, Erika A. Scholl

Publikováno v: Neurotoxicology

Exposure to nerve agents (NAs) and other organophosphates (OPs) can initiate seizures that rapidly progress to status epilepticus (SE). While the electrographic and neuropathological sequelae of SE evoked by NAs and OPs have been characterized in adu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f186933027ca73207e5166a933b81e
https://doi.org/10.1016/j.neuro.2018.02.018

Zobrazit plný text záznamu

Dopaminergic Co-Regulation of Locomotor Development and Motor Neuron Synaptogenesis is Uncoupled by Hypoxia in Zebrafish

Autor: Jong-Hyun Son, Miranda D. Bowles, Erika A. Scholl, Joshua L. Bonkowsky, Tamara J. Stevenson

Publikováno v: eNeuro

Hypoxic injury to the developing human brain is a complication of premature birth and is associated with long-term impairments of motor function. Disruptions of axon and synaptic connectivity have been linked to developmental hypoxia, but the fundame

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e7090411b1f3e050648a02b53fb563
https://doi.org/10.1523/eneuro.0355-19.2020

Zobrazit plný text záznamu

Introduction of lipidization-cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities

Autor: Brad R. Green, Grzegorz Bulaj, Liuyin Zhang, Erika A. Scholl, Karen White, Daniel R. McDougle, Timothy H. Pruess, H. Steve White, Brian D. Klein

Publikováno v: Journal of Peptide Science. 16:486-495

The neuropeptides galanin (GAL), neuropeptide Y (NPY) or neurotensin (NT) exhibit anticonvulsant activities mediated by their respective receptors in the brain. To transform these peptides into potential neurotherapeutics, their systemic bioavailabil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::948519ebcf72788937466e2e333cfd6e
https://doi.org/10.1002/psc.1266

Zobrazit plný text záznamu

Developing novel antiepileptic drugs: Characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models

Autor: Brad R. Green, Sean P. Flynn, Liuyin Zhang, Timothy H. Pruess, Grzegorz Bulaj, H. Steve White, Erika A. Scholl, Brian D. Klein

Publikováno v: Neurotherapeutics. 6:372-380

The endogenous neuropeptide galanin and its associated receptors galanin receptor 1 and galanin receptor 2 are highly localized in brain limbic structures and play an important role in the control of seizures in animal epilepsy models. As such, galan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9dbdd37065541696d655fa12ccf1f1
https://doi.org/10.1016/j.nurt.2009.01.001

Zobrazit plný text záznamu

Neuronal degeneration is observed in multiple regions outside the hippocampus after lithium pilocarpine-induced status epilepticus in the immature rat

Autor: Erika A. Scholl, F. E. Dudek, Jeffrey J. Ekstrand

Although hippocampal sclerosis is frequently identified as a possible epileptic focus in patients with temporal lobe epilepsy, neuronal loss has also been observed in additional structures, including areas outside the temporal lobe. The claim from se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc8d4800c10322bc503cd89f41cda4d
https://europepmc.org/articles/PMC3916148/

Zobrazit plný text záznamu

Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery

Autor: Timothy H. Pruess, H. Steve White, Brad R. Green, Grzegorz Bulaj, Charles R. Robertson, Erika A. Scholl

Publikováno v: Journal of medicinal chemistry. 53(4)

Galanin modulates seizures in the brain through two galanin receptor subtypes, GalR1 and GalR2. To generate systemically-active galanin receptor ligands that discriminate between GalR1 and GalR2, the GalR1-preferring analogue, Gal-B2 (or NAX 5055), w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6f432acabf1352e4befc03a6d7cea6
https://pubmed.ncbi.nlm.nih.gov/20121116

Zobrazit plný text záznamu

Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities

Autor: Marianna Dorota Sochanska, Hee Kyoung Lee, Sean P. Flynn, Liuyin Zhang, Grzegorz Bulaj, Timothy H. Pruess, Misty D. Smith, Erika A. Scholl, Brad R. Green, Karen White, Charles R. Robertson, H. Steve White

Publikováno v: Journal of medicinal chemistry. 51(24)

Galanin is an endogenous neuropeptide that modulates seizures in the brain. Because this neuropeptide does not penetrate the blood-brain barrier, we designed truncated galanin analogues in which nonessential amino acid residues were replaced by catio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1652635b1803a3952763f90b6d0378d5
https://pubmed.ncbi.nlm.nih.gov/19053761

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání