Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Erika, Benko"'
Autor:
Vitaliy A. Matveev, Erik Z. Mihelic, Erika Benko, Patrick Budylowski, Sebastian Grocott, Terry Lee, Chapin S. Korosec, Karen Colwill, Henry Stephenson, Ryan Law, Lesley A. Ward, Salma Sheikh-Mohamed, Geneviève Mailhot, Melanie Delgado-Brand, Adrian Pasculescu, Jenny H. Wang, Freda Qi, Tulunay Tursun, Lela Kardava, Serena Chau, Philip Samaan, Annam Imran, Dennis C. Copertino, Jr., Gary Chao, Yoojin Choi, Robert J. Reinhard, Rupert Kaul, Jane M. Heffernan, R. Brad Jones, Tae-Wook Chun, Susan Moir, Joel Singer, Jennifer Gommerman, Anne-Claude Gingras, Colin Kovacs, Mario Ostrowski
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107915- (2023)
Summary: Older individuals and people with HIV (PWH) were prioritized for COVID-19 vaccination, yet comprehensive studies of the immunogenicity of these vaccines and their effects on HIV reservoirs are not available. Our study on 68 PWH and 23 HIV-ne
Externí odkaz:
https://doaj.org/article/c0a02cfb1ee4418788ae8efa6e553405
Autor:
Natalie F. McMyn, Joseph Varriale, Emily J. Fray, Carolin Zitzmann, Hannah MacLeod, Jun Lai, Anushka Singhal, Milica Moskovljevic, Mauro A. Garcia, Brianna M. Lopez, Vivek Hariharan, Kyle Rhodehouse, Kenneth Lynn, Pablo Tebas, Karam Mounzer, Luis J. Montaner, Erika Benko, Colin Kovacs, Rebecca Hoh, Francesco R. Simonetti, Gregory M. Laird, Steven G. Deeks, Ruy M. Ribeiro, Alan S. Perelson, Robert F. Siliciano, Janet M. Siliciano
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 17 (2023)
HIV-1 persists in a latent reservoir in resting CD4+ T cells despite antiretroviral therapy (ART). The reservoir decays slowly over the first 7 years of ART (t1/2 = 44 months). However, whether decay continues with long-term ART is unclear. Recent in
Externí odkaz:
https://doaj.org/article/16cb14484f3b4a688aeb5fd64cf309ef
Autor:
Dennis C. Copertino Jr., Carissa S. Holmberg, Jared Weiler, Adam R. Ward, J. Natalie Howard, Callie Levinger, Alina P.S. Pang, Michael J. Corley, Friederike Dündar, Paul Zumbo, Doron Betel, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, Noemi Linden, Bernard J. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, Colin Kovacs, Erika Benko, Alberto Bosque, R. Brad Jones, for the AIDS Clinical Trials Group (ACTG) A5321 Team
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
IL-15 is under clinical investigation toward the goal of curing HIV infection because of its abilities to reverse HIV latency and enhance immune effector function. However, increased potency through combination with other agents may be needed. 3-Hydr
Externí odkaz:
https://doaj.org/article/ed18029fbf2043e591567763be3f9138
Autor:
Natalie N. Kinloch, Yanqin Ren, Winiffer D. Conce Alberto, Winnie Dong, Pragya Khadka, Szu Han Huang, Talia M. Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin Kovacs, Erika Benko, Mario A. Ostrowski, Perla M. Del Rio Estrada, Avery Wimpelberg, Christopher Cannon, W. David Hardy, Lynsay MacLaren, Harris Goldstein, Chanson J. Brumme, Guinevere Q. Lee, Rebecca M. Lynch, Zabrina L. Brumme, R. Brad Jones
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The intact proviral DNA assay quantifies the genomically intact HIV reservoir, but assay failure due to HIV-1 polymorphism has been observed. Here, the authors report a 28% failure rate in a cohort of people with HIV-1, and note within-host HIV-1 div
Externí odkaz:
https://doaj.org/article/2f1b4a3b13f745078fbaecf15223c1ef
Autor:
Fat Malazogu, Rodney K. Rousseau, Nitin Shivappa, Sanja Huibner, Sharon L. Walmsley, Colin M. Kovacs, Erika Benko, Robert J. Reinhard, Ron Rosenes, James R. Hebert, Rupert Kaul
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Immunologic non-responders (INRs) are a subset of individuals living with HIV who have suboptimal blood CD4+ T cell recovery despite effective antiretroviral therapy (ART). They are at an increased risk of serious non-AIDS co-morbidities and death, a
Externí odkaz:
https://doaj.org/article/35f7b33722804e73be5e65344d4488e1
Autor:
Andrew Wilson, Leyn Shakhtour, Adam Ward, Yanqin Ren, Melina Recarey, Eva Stevenson, Maria Korom, Colin Kovacs, Erika Benko, R. Brad Jones, Rebecca M. Lynch
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Although antiretroviral therapy (ART) successfully suppresses HIV-1 replication, ART-treated individuals must maintain therapy to avoid rebound from an integrated viral reservoir. Strategies to limit or clear this reservoir are urgently needed. Indiv
Externí odkaz:
https://doaj.org/article/cb3a33d59886497f942ad411a9a3afad
Autor:
David Lessard, Karine Dubé, Martin Bilodeau, Patrick Keeler, Shari Margolese, Ron Rosenes, Liliya Sinyavskaya, Madeleine Durand, Erika Benko, Colin Kovacs, Charlotte Guerlotté, Wangari Tharao, Keresa Arnold, Renée Masching, Darien Taylor, José Sousa, Mario Ostrowski, Jeff Taylor, Andy Kaytes, Davey Smith, Sara Gianella, Nicolas Chomont, Jonathan B. Angel, Jean-Pierre Routy, Éric A. Cohen, Bertrand Lebouché, Cecilia T. Costiniuk
Publikováno v:
AIDS research and human retroviruses, vol 38, iss 8
HIV cure research requires interrogating latent HIV reservoirs in deep tissues, which necessitates autopsies to avoid risks to participants. An HIV autopsy biobank would facilitate this research, but such research raises ethical issues and requires p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d4aaf894ebc2e8175ddd71bb74ed5f
https://pubmed.ncbi.nlm.nih.gov/35778845
https://pubmed.ncbi.nlm.nih.gov/35778845
Autor:
Michael C. Sneller, Jana Blazkova, J. Shawn Justement, Victoria Shi, Brooke D. Kennedy, Kathleen Gittens, Jekaterina Tolstenko, Genevieve McCormack, Emily J. Whitehead, Rachel F. Schneck, Michael A. Proschan, Erika Benko, Colin Kovacs, Cihan Oguz, Michael S. Seaman, Marina Caskey, Michel C. Nussenzweig, Anthony S. Fauci, Susan Moir, Tae-Wook Chun
Publikováno v:
Nature. 606:375-381
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1debf122b8165144c14fa8fd497e2b2
https://doi.org/10.1038/s41586-022-04797-9
https://doi.org/10.1038/s41586-022-04797-9
Autor:
Natalie N. Kinloch, Yanqin Ren, Winiffer D. Conce Alberto, Winnie Dong, Pragya Khadka, Szu Han Huang, Talia M. Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin Kovacs, Erika Benko, Mario A. Ostrowski, Perla M. Del Rio Estrada, Avery Wimpelberg, Christopher Cannon, W. David Hardy, Lynsay MacLaren, Harris Goldstein, Chanson J. Brumme, Guinevere Q. Lee, Rebecca M. Lynch, Zabrina L. Brumme, R. Brad Jones
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/d63b13d33e68408f9ca3dd6ccf322f0f
Autor:
Sanja Huibner, Robert Reinhard, Rodney K. Rousseau, Terry Lee, Rupert Kaul, Fat Malazogu, Connie J. Kim, Ron Rosenes, Joel Singer, Erika Benko, Colin Kovacs, Sharon Walmsley
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 89:199-207
To assess whether probiotic supplementation may reduce disease-linked systemic immune activation in people living with HIV with the immunologic nonresponder phenotype.Phase 2b, randomized, double-blind, placebo-controlled pilot trial.HIV-positive ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e461cc7ce7c5cb288b28a8ad647bb4
https://doi.org/10.1097/qai.0000000000002840
https://doi.org/10.1097/qai.0000000000002840