Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Erik van Dijk"'
Autor:
Kristiaan J. Lenos, Sander Bach, Leandro Ferreira Moreno, Sanne ten Hoorn, Nina R. Sluiter, Sanne Bootsma, Felipe A. Vieira Braga, Lisanne E. Nijman, Tom van den Bosch, Daniel M. Miedema, Erik van Dijk, Bauke Ylstra, Ruth Kulicke, Fred P. Davis, Nicolas Stransky, Gromoslaw A. Smolen, Robert R. J. Coebergh van den Braak, Jan N. M. IJzermans, John W. M. Martens, Sally Hallam, Andrew D. Beggs, Geert J. P. L. Kops, Nico Lansu, Vivian P. Bastiaenen, Charlotte E. L. Klaver, Maria C. Lecca, Khalid El Makrini, Clara C. Elbers, Mark P. G. Dings, Carel J. M. van Noesel, Onno Kranenburg, Jan Paul Medema, Jan Koster, Lianne Koens, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. de Hingh, Maarten F. Bijlsma, Jurriaan B. Tuynman, Louis Vermeulen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Colorectal cancer can lead to the development of peritoneal metastases, which are associated with worse disease outcome. Here, the authors characterize peritoneal metastases from 52 patients using RNA-seq and mutational sequencing and show a distinct
Externí odkaz:
https://doaj.org/article/369abe186b03465f8bac79e90a4d4606
Autor:
Wendy B. C. Stevens, G. Tjitske Los-de Vries, Carole Langois-Jacques, Andrew J. Clear, Phylicia Stathi, Birgitta Sander, Andreas Rosenwald, Maria Calaminici, Eva Hoster, Wolfgang Hiddemann, Philippe Gaulard, Gilles Salles, Wolfram Klapper, Luc Xerri, Catherine Burton, Reuben M. Tooze, Alexandra G. Smith, Christian Buske, David W. Scott, Yasodha Natkunam, Ranjana Advani, Laurie H. Sehn, John Raemaekers, John Gribben, Sandra Lockmer, Eva Kimby, Marie José Kersten, Delphine Maucort-Boulch, Bauke Ylstra, Erik van Dijk, Daphne de Jong
Publikováno v:
HemaSphere, Vol 7, Iss 4, p e863 (2023)
Externí odkaz:
https://doaj.org/article/ebf13b82395e42caa214d0852fc3edd2
Autor:
Esther E. E. Drees, Yvonne W. S. Jauw, Erik van Dijk, Sven Borchmann, Sandra A. W. M. Verkuijlen, Phylicia Stathi, Nils J. Groenewegen, Nathalie J. Hijmering, Daniella R. A. I. Berry, Eric J. Meershoek, Danielle Hoogmoed, Anne Kwakman, Tessa J. Molenaar, Dirk M. Pegtel, Bauke Ylstra, Daphne de Jong, Josée M. Zijlstra, Margaretha G. M. Roemer
Publikováno v:
HemaSphere, Vol 6, Iss 7, p e749 (2022)
Externí odkaz:
https://doaj.org/article/26363f9c16cc417598430c0d786f8904
Autor:
Charlotte I Stroes, Sandor Schokker, Mohammed Khurshed, Stephanie O van der Woude, Ron AA Mathôt, Marije Slingerland, Judith de Vos-Geelen, Massimo Zucchetti, Cristina Matteo, Erik van Dijk, Bauke Ylstra, Victor Thijssen, Sarah Derks, Tesfay Godefa, Willemieke Dijksterhuis, Gerben E Breimer, Otto M van Delden, Rob HA Verhoeven, Sybren L Meijer, Maarten F Bijlsma, Hanneke WM van Laarhoven
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Purpose: Regorafenib monotherapy, a multikinase inhibitor of angiogenesis, tumor microenvironment, and tumorigenesis, showed promising results in gastric cancer. We aimed to assess the tolerability of regorafenib and paclitaxel in patients with advan
Externí odkaz:
https://doaj.org/article/aed72a810b8b46b7a7487a5ebbe32545
Autor:
Erik van Dijk, Tom van den Bosch, Kristiaan J. Lenos, Khalid El Makrini, Lisanne E. Nijman, Hendrik F. B. van Essen, Nico Lansu, Michiel Boekhout, Joris H. Hageman, Rebecca C. Fitzgerald, Cornelis J. A. Punt, Jurriaan B. Tuynman, Hugo J. G. Snippert, Geert J. P. L. Kops, Jan Paul Medema, Bauke Ylstra, Louis Vermeulen, Daniël M. Miedema
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Intratumour heterogeneity (ITH) is associated with worse prognosis in cancer, and efficient frameworks to measure it are needed. Here the authors develop a method to estimate copy number heterogeneity, and propose that it is driven by chromosomal ins
Externí odkaz:
https://doaj.org/article/264d1331d97845559b189b69b84d9dcb
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 4 (2021)
We recently introduced a method to derive intra-tumor heterogeneity (ITH) from a single copy number measurement. This method stratifies patients for survival and could potentially help to identify low and high-risk patients with clinical relevance.
Externí odkaz:
https://doaj.org/article/6565d7e6ce88476081f21f138217e72c
Autor:
Juami Hermine Mariama van Gils, Erik van Dijk, Alessia Peduzzo, Alexander Hofmann, Nicola Vettore, Marie P Schützmann, Georg Groth, Halima Mouhib, Daniel E Otzen, Alexander K Buell, Sanne Abeln
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007767 (2020)
Many proteins have the potential to aggregate into amyloid fibrils, protein polymers associated with a wide range of human disorders such as Alzheimer's and Parkinson's disease. The thermodynamic stability of amyloid fibrils, in contrast to that of f
Externí odkaz:
https://doaj.org/article/5afd982d287348af94862bd4c9dee1a0
Autor:
Margriet M Palm, Marchien G Dallinga, Erik van Dijk, Ingeborg Klaassen, Reinier O Schlingemann, Roeland M H Merks
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0159478 (2016)
Angiogenesis involves the formation of new blood vessels by sprouting or splitting of existing blood vessels. During sprouting, a highly motile type of endothelial cell, called the tip cell, migrates from the blood vessels followed by stalk cells, an
Externí odkaz:
https://doaj.org/article/4bfb1322ee1047a589ddd3b828fea4e3
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 5, p e1004277 (2015)
The hydrophobic effect is the main driving force in protein folding. One can estimate the relative strength of this hydrophobic effect for each amino acid by mining a large set of experimentally determined protein structures. However, the hydrophobic
Externí odkaz:
https://doaj.org/article/7992f44f76764707aa52352d63c03a00
Autor:
Erik van Dijk, Erik van Werkhoven, Rebecca Asher, Jennifer K. Mooi, David Espinoza, Hendrik F. van Essen, Harm van Tinteren, Nicole C. T. van Grieken, Cornelis J. A. Punt, Niall C. Tebbutt, Bauke Ylstra
Publikováno v:
van Dijk, E, van Werkhoven, E, Asher, R, Mooi, J K, Espinoza, D, van Essen, H F, van Tinteren, H, van Grieken, N C T, Punt, C J A, Tebbutt, N C & Ylstra, B 2022, ' Predictive value of chromosome 18q11.2-q12.1 loss for benefit from bevacizumab in metastatic colorectal cancer : A post hoc analysis of the randomized phase III-trial AGITG-MAX ', International Journal of Cancer, vol. 151, no. 7, pp. 1166-1174 . https://doi.org/10.1002/ijc.34061
International Journal of Cancer, 151(7), 1166-1174. Wiley-Liss Inc.
International Journal of Cancer, 151(7), 1166-1174. Wiley-Liss Inc.
The VEGF-A monoclonal antibody bevacizumab is currently recommended for first-line treatment of all metastatic colorectal cancer (mCRC) patients. Cost-benefit ratio and side-effects however necessitate patient selection. A large retrospective yet non