Zobrazeno 1 - 10
of 352
pro vyhledávání: '"Erik de Leeuw"'
Autor:
Esther Janssen, Jan Willem van Dalen, Mengfei Cai, Mina A. Jacob, José Marques, Marco Duering, Edo Richard, Anil M. Tuladhar, Frank-Erik de Leeuw, Nina Hilkens
Publikováno v:
Blood Pressure, Vol 33, Iss 1 (2024)
AbstractPurpose: There is evidence that blood pressure variability (BPV) is associated with cerebral small vessel disease (SVD) and may therefore increase the risk of stroke and dementia. It remains unclear if BPV is associated with SVD progression o
Externí odkaz:
https://doaj.org/article/e302cd24398346f7939a3a3384f0aaf9
Autor:
Theresa J. van Lith, Hao Li, Marte W. van der Wijk, Naomi T. Wijers, Wouter M. Sluis, Marieke J. H. Wermer, Frank-Erik de Leeuw, Frederick J. A. Meijer, Anil M. Tuladhar
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
ObjectivesSARS-CoV-2 infection is associated with a decline in functional outcomes; many patients experience persistent symptoms, while the underlying pathophysiology remains unclear. This study investigated white matter (WM) integrity on brain MRI i
Externí odkaz:
https://doaj.org/article/0ff458ecce044cecb73a7c59aef4b719
Autor:
Gemma Solé-Guardia, Matthijs Luijten, Bram Geenen, Jurgen A. H. R. Claassen, Geert Litjens, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract White matter hyperintensities (WMH) are the most prevalent markers of cerebral small vessel disease (SVD), which is the major vascular risk factor for dementia. Microvascular pathology and neuroinflammation are suggested to drive the transit
Externí odkaz:
https://doaj.org/article/7ff59429590144cd9d0b636d08691e0d
Autor:
Roy P C Kessels, Audrey Low, Hugh Markus, Anil Tuladhar, Frank‐Erik de Leeuw, Robin G Morris, Ziad Mallat, Niels P Riksen, Daniel J Tozer, Sanne van Winden, Lupei Cai, Marnix C Maas, Meritxell Nus, Anja van der Kolk, Rowan Wolters
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction The INflammation and Small Vessel Disease (INSVD) study aims to investigate whether peripheral inflammation, immune (dys)regulation and blood–brain barrier (BBB) permeability relate to disease progression in cerebral small vessel disea
Externí odkaz:
https://doaj.org/article/9de6a34a9f7443a3934e4e2d8c33f96d
Autor:
Chentao He, Rui Yang, Siming Rong, Piao Zhang, Xi Chen, Qi Qi, Ziqi Gao, Yan Li, Hao Li, Frank-Erik de Leeuw, Anil M. Tuladhar, Marco Duering, Rick C. Helmich, Rick van der Vliet, Sirwan K.L. Darweesh, Zaiyi Liu, Lijuan Wang, Mengfei Cai, Yuhu Zhang
Publikováno v:
NeuroImage: Clinical, Vol 44, Iss , Pp 103679- (2024)
Background: Previous research revealed differences in cerebellar white matter integrity by disease stages, indicating a compensatory role in Parkinson’s disease (PD). However, the temporal evolution of cerebellar white matter microstructure in pati
Externí odkaz:
https://doaj.org/article/5fb3e90d29704159a84acee1fd9f177f
Autor:
Rui Li, Eric Harshfield, Steven Bell, Michael Burkhart, Anil Tuladhar, Saima Hilal, Daniel Tozer, Francesca Chappell, Stephen Makin, Jessica Lo, Joanna Wardlaw, Frank-Erik de Leeuw, Christopher Chen, Zoe Kourtzi, Hugh Markus
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100235- (2024)
Introduction: Cerebral small vessel disease (SVD) contributes to 45% of dementia cases worldwide. Only a minority of SVD patients develop dementia, yet we lack a reliable model for predicting incident dementia in SVD. Most attempts to date have relie
Externí odkaz:
https://doaj.org/article/258f4cb4ab2146e6af7cf5085e948f47
Autor:
Gemma Sole-Guardia, Emma Custers, Arthur de Lange, Elyne Clijncke, Bram Geenen, Jose Gutierrez, Benno Kusters, Jurgen Claassen, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda Kiliaan
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100313- (2024)
Introduction: The major vascular cause of dementia is cerebral small vessel disease (SVD). The diagnosis of SVD relies on MRI findings, including white matter hyperintensities (WMH) amongst others. Chronic hypertension and neuroinflammation are recog
Externí odkaz:
https://doaj.org/article/de574cd8413c4afcb32aff06ed68dc6f
Autor:
Michelle G. Jansen, Ludovica Griffanti, Clare E. Mackay, Melis Anatürk, Luca Melazzini, Ann-Marie G. de Lange, Nicola Filippini, Enikő Zsoldos, Kim Wiegertjes, Frank-Erik de Leeuw, Archana Singh-Manoux, Mika Kivimäki, Klaus P. Ebmeier, Sana Suri
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100080- (2024)
Externí odkaz:
https://doaj.org/article/21a8b0b8655a414f8ef9deec10c3b857
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100205- (2024)
Background: High blood pressure variability (BPV) may be a risk factor for stroke and dementia in patients with ischemic stroke, but the underlying mechanism is unknown. We aimed to investigate whether high BPV is associated with presence and progres
Externí odkaz:
https://doaj.org/article/fa7d62ea73724d0e9f56e1a9c993c760
Autor:
Gemma Solé-Guardia, Emma Custers, Arthur de Lange, Elyne Clijncke, Bram Geenen, Jose Gutierrez, Benno Küsters, Jurgen A. H. R. Claassen, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract The major vascular cause of dementia is cerebral small vessel disease (SVD), including white matter hyperintensities (WMH) amongst others. While the underlying pathology of SVD remains unclear, chronic hypertension and neuroinflammation are
Externí odkaz:
https://doaj.org/article/f8b63c80620f4e1d9ffcea9812722dfc