Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Erik Toraason"'
BRCA1/BRC-1 and SMC-5/6 regulate DNA repair pathway engagement during Caenorhabditis elegans meiosis
Autor:
Erik Toraason, Alina Salagean, David E Almanzar, Jordan E Brown, Colette M Richter, Nicole A Kurhanewicz, Ofer Rog, Diana E Libuda
Publikováno v:
eLife, Vol 13 (2024)
The preservation of genome integrity during sperm and egg development is vital for reproductive success. During meiosis, the tumor suppressor BRCA1/BRC-1 and structural maintenance of chromosomes 5/6 (SMC-5/6) complex genetically interact to promote
Externí odkaz:
https://doaj.org/article/5cc501e585fc4bf7b72400fd15e82b53
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010282 (2022)
Female reproductive aging is associated with decreased oocyte quality and fertility. The nematode Caenorhabditis elegans is a powerful system for understanding the biology of aging and exhibits age-related reproductive defects that are analogous to t
Externí odkaz:
https://doaj.org/article/5823b7b459b84e4cbd0a2a2c270e9dc8
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100801- (2021)
Summary: Accurate repair of DNA double-strand breaks (DSBs) in developing germ cells is critical to promote proper chromosome segregation and to maintain genome integrity. To directly detect homolog-independent (intersister/intrachromatid) meiotic DS
Externí odkaz:
https://doaj.org/article/1f3eae90e0394b6ab6ba79e75998ef00
Autor:
Jennifer K Pleiman, Amy A Irving, Zhishi Wang, Erik Toraason, Linda Clipson, William F Dove, Dustin A Deming, Michael A Newton
Publikováno v:
PLoS Genetics, Vol 14, Iss 9, p e1007611 (2018)
Conservation over three mammalian genera-the mouse, rat, and human-has been found for a subset of the transcripts whose level differs between the adenoma and normal epithelium of the colon. Pde4b is one of the triply conserved transcripts whose level
Externí odkaz:
https://doaj.org/article/8f6eb91913e744ebb694031853f1d680
Autor:
Shiyi Zhou, Yanping Zhang, Rachel Kaletsky, Erik Toraason, Wenhong Zhang, Meng-Qiu Dong, Coleen T. Murphy
Memory loss is one of the most debilitating symptoms of aging. While we normally think of memory regulation as autonomous to the brain, other factors outside of the brain can also affect neuron function. We have shown that the longevity insulin/IGF-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031e8bfd7205d135ae4b8e6f0d3401f8
https://doi.org/10.1101/2023.02.16.528821
https://doi.org/10.1101/2023.02.16.528821
The preservation of genome integrity during sperm and egg development is vital for reproductive success. During meiosis, the tumor suppressor BRCA1/BRC-1 and structural maintenance of chromosomes 5/6 (SMC-5/6) complex genetically interact to promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a485b18159ea28800fad196ae8c86a5b
https://doi.org/10.1101/2022.06.12.495837
https://doi.org/10.1101/2022.06.12.495837
Autor:
Adam M Saunders, Cori K. Cahoon, Victoria L. Adler, Acadia L DiNardo, Nicole A. Kurhanewicz, Erik Toraason, Diana E. Libuda
Publikováno v:
Genetics
Arranged in a spatial-temporal gradient for germ cell development, the adult germline of Caenorhabditis elegans is an excellent system for understanding the generation, differentiation, function, and maintenance of germ cells. Imaging whole C. elegan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67faac1c1cbeaaca83fa54d0b85f4473
https://doi.org/10.1093/genetics/iyab010
https://doi.org/10.1093/genetics/iyab010
Autor:
Cori K. Cahoon, Victoria L. Adler, Acadia L DiNardo, Erik Toraason, Adam M Saunders, Diana E. Libuda, Nicole A. Kurhanewicz
Arranged in a spatial-temporal gradient for germ cell development, the adult germline ofCaenorhabditis elegansis an excellent system for understanding the generation, differentiation, function, and maintenance of germ cells. Imaging wholeC. elegansge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1811d6f3e5e23539f901d3f463ee55cf
https://doi.org/10.1101/2020.11.25.398685
https://doi.org/10.1101/2020.11.25.398685
Autor:
Diana E. Libuda, Erik Toraason, Marissa L. Glover, Alina Salagean, Cordell Clark, Anna Horacek
SummaryDuring meiosis, the maintenance of genome integrity is critical for generating viable haploid gametes [1]. In meiotic prophase I, double-strand DNA breaks (DSBs) are induced and a subset of these DSBs are repaired as interhomolog crossovers to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd948268ee628e08835af27c2691ddd
https://doi.org/10.1101/2020.07.22.216143
https://doi.org/10.1101/2020.07.22.216143
Autor:
Cordell Clark, Marissa L. Glover, Victoria L. Adler, Alina Salagean, Tolkappiyan Premkumar, Anna Horacek, Diana E. Libuda, Francesca Cole, Erik Toraason
Publikováno v:
Current Biology. 31:1508-1514.e5
During meiosis, the maintenance of genome integrity is critical for generating viable haploid gametes.1 In meiotic prophase I, double-strand DNA breaks (DSBs) are induced and a subset of these DSBs are repaired as interhomolog crossovers to ensure pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a11ea2caeca8da5a9f0f7eb161ff60c
https://doi.org/10.1016/j.cub.2021.03.008
https://doi.org/10.1016/j.cub.2021.03.008