Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Erik Toorens"'
Autor:
Jun Guo, Anahita Fathi Kazerooni, Erik Toorens, Hamed Akbari, Fanyang Yu, Chiharu Sako, Elizabeth Mamourian, Russell T. Shinohara, Constantinos Koumenis, Stephen J. Bagley, Jennifer J. D. Morrissette, Zev A. Binder, Steven Brem, Suyash Mohan, Robert A. Lustig, Donald M. O’Rourke, Tapan Ganguly, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Glioblastoma is a highly heterogeneous disease, with variations observed at both phenotypical and molecular levels. Personalized therapies would be facilitated by non-invasive in vivo approaches for characterizing this heterogeneity. In this
Externí odkaz:
https://doaj.org/article/f5997dcf88784ed0a9eb262aa340f854
Autor:
Anahita Fathi Kazerooni, Sanjay Saxena, Erik Toorens, Danni Tu, Vishnu Bashyam, Hamed Akbari, Elizabeth Mamourian, Chiharu Sako, Costas Koumenis, Ioannis Verginadis, Ragini Verma, Russell T. Shinohara, Arati S. Desai, Robert A. Lustig, Steven Brem, Suyash Mohan, Stephen J. Bagley, Tapan Ganguly, Donald M. O’Rourke, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Multi-omic data, i.e., clinical measures, radiomic, and genetic data, capture multi-faceted tumor characteristics, contributing to a comprehensive patient risk assessment. Here, we investigate the additive value and independent reproducibili
Externí odkaz:
https://doaj.org/article/2e0a631fb2f84bd8ab1d9f8f31d56f26
Autor:
Nicholas F. Lahens, Emanuela Ricciotti, Olga Smirnova, Erik Toorens, Eun Ji Kim, Giacomo Baruzzo, Katharina E. Hayer, Tapan Ganguly, Jonathan Schug, Gregory R. Grant
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background Though Illumina has largely dominated the RNA-Seq field, the simultaneous availability of Ion Torrent has left scientists wondering which platform is most effective for differential gene expression (DGE) analysis. Previous investi
Externí odkaz:
https://doaj.org/article/a393f7f9eb774f5e88b0c7d032c82bef
Autor:
Jayaram Thimmapuram, Robert Pargament, Kedesha Sibliss, Rodney Grim, Rosana Risques, Erik Toorens
Publikováno v:
Journal of Community Hospital Internal Medicine Perspectives, Vol 7, Iss 1, Pp 21-27 (2017)
Background: Burnout poses significant challenges during training years in residency and later in the career. Meditation is a tool to treat stress-related conditions and promote wellness. Telomere length may be affected by burnout and stress. However,
Externí odkaz:
https://doaj.org/article/64f0bdc8c455402497f211a32a4ad58b
Autor:
Zheng Lao, Catherine J Kelly, Xiang-Yang Yang, W Timothy Jenkins, Erik Toorens, Tapan Ganguly, Sydney M Evans, Cameron J Koch
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133895 (2015)
Diagnostic and prognostic indicators are key components to achieve the goal of personalized cancer therapy. Two distinct approaches to this goal include predicting response by genetic analysis and direct testing of possible therapies using cultures d
Externí odkaz:
https://doaj.org/article/31c38590bc004d79a5dcbfee33149fc5
Autor:
Anahita Fathi Kazerooni, Hamed Akbari, Xiaoju Hu, Vikas Bommineni, Dimitris Grigoriadis, Erik Toorens, Chiharu Sako, Elizabeth Mamourian, Dominique Ballinger, Robyn Sussman, Ashish Singh, Ioannis I. Verginadis, Nadia Dahmane, Constantinos Koumenis, Zev A. Binder, Stephen J. Bagley, Suyash Mohan, Artemis Hatzigeorgiou, Donald M. O’Rourke, Tapan Ganguly, Subhajyoti De, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Glioblastoma (GBM) is well-known for its molecular and spatial heterogeneity, which poses a challenge for precision therapies and clinical trial stratification. Here, in a comprehensive radiogenomics study of 358 GBMs, we investigated the association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86afe81a4b12db445d1da11fbc1ede10
https://doi.org/10.1101/2022.12.15.517767
https://doi.org/10.1101/2022.12.15.517767
Autor:
Tapan Ganguly, Russell T. Shinohara, Costas Koumenis, Sanjay Saxena, Vishnu Bashyam, Erik Toorens, Anahita Fathi Kazerooni, Ioannis I. Verginadis, Elizabeth Mamourian, Donald M. O'Rourke, Suyash Mohan, Christos Davatzikos, Hamed Akbari, Stephen J Bagley, MacLean Nasrallah, Spyridon Bakas, Danni Tu, Steven Brem, Chiharu Sako, Arati Desai, Robert A. Lustig, Ragini Verma
Background. Multi-omic data, i.e., clinical measures, radiomic, and genetic data, capture multi-faceted tumor characteristics, contributing to a comprehensive patient risk assessment. Here, we investigate the additive value and independent reproducib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9505a0588b792b6bdb4ef7f620dc2dc5
https://doi.org/10.21203/rs.3.rs-908405/v1
https://doi.org/10.21203/rs.3.rs-908405/v1
Autor:
Jun Guo, Anahita Fathi Kazerooni, Hamed Akbari, Erik Toorens, Chiharu Sako, Elizabeth Mamourian, Constantinos Koumenis, Stephen Bagley, Zev A Binder, Robert Lustig, Donald O'Rourke, Tapan Ganguly, Spyridon Bakas, MacLean Nasrallah, Christos Davatzikos
Publikováno v:
Neuro-Oncology. 24:vii171-vii171
PURPOSE The significant heterogeneity of glioblastoma is typically displayed on both phenotypical and molecular levels. Non-invasive in vivo approaches to characterize this heterogeneity would potentially facilitate personalized therapies. Here we le
Autor:
Fanyang Yu, Anahita Fathi Kazerooni, Erik Toorens, Hamed Akbari, Chiharu Sako, Elizabeth Mamourian, Stephen Bagley, Zev A Binder, Robert A Lustig, Steven Brem, Donald M O’Rourke, Tapan Ganguly, Spyridon Bakas, MacLean Nasrallah, Pratik Chaudhari, Christos Davatzikos
Publikováno v:
Neuro-Oncology. 24:vii166-vii166
PURPOSE There is evidence that molecular heterogeneity of glioblastoma is associated with heterogeneity of MR imaging signatures. Modern machine learning models, such as deep neural networks, provide a tool for capturing such complex relationships in
Autor:
Anahita Fathi Kazerooni, Hamed Akbari, Erik Toorens, Dimitris Grigoriadis, Xiaoju Hu, Chiharu Sako, Elizabeth Mamourian, Stephen Bagley, Zev A Binder, Robert Lustig, Steven Brem, Donald O'Rourke, Tapan Ganguly, Subhajyoti De, Artemis Hatzigeorgiou, Spyridon Bakas, MacLean Nasrallah, Christos Davatzikos
Publikováno v:
Neuro-Oncology. 24:vii184-vii184
Somatic genomic alterations acquired during GBM growth enhance adaptation of tumor cells to their microenvironment and give rise to molecular heterogeneity. Radiogenomics could facilitate exploration of the underlying pathobiology of tumor growth in