Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Erik Smedler"'
Autor:
David Forsberg, Zachi Horn, Evangelia Tserga, Erik Smedler, Gilad Silberberg, Yuri Shvarev, Kai Kaila, Per Uhlén, Eric Herlenius
Publikováno v:
eLife, Vol 5 (2016)
Inflammation-induced release of prostaglandin E2 (PGE2) changes breathing patterns and the response to CO2 levels. This may have fatal consequences in newborn babies and result in sudden infant death. To elucidate the underlying mechanisms, we presen
Externí odkaz:
https://doaj.org/article/effcdb1c5c5a4631a2ce7c5a0f08f10b
Publikováno v:
Journal of Affective Disorders. 324:449-454
Bipolar disorder is a severe psychiatric syndrome defined by periodic mood shifts. Patients with bipolar disorder show cognitive impairments relative to healthy controls. The risk of developing schizophrenia, and partially also bipolar disorder, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dde09b7261c33a2795a5d6dd6889c94
https://doi.org/10.1016/j.jad.2022.12.113
https://doi.org/10.1016/j.jad.2022.12.113
Autor:
Erik Joas, Lina Jonsson, Alexander Viktorin, Erik Smedler, Erik Pålsson, Guy M. Goodwin, Mikael Landén
Publikováno v:
The Pharmacogenomics Journal. 23:28-35
Antidepressant medication is used extensively to treat bipolar depression despite uncertain efficacy. The cytochrome P450 (CYP) 2C19 enzyme metabolize several antidepressants, and polymorphisms in the corresponding gene CYP2C19 influence plasma conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f8f0e40a85f2bcfa557c01e9a0a1a3
https://doi.org/10.1038/s41397-022-00294-4
https://doi.org/10.1038/s41397-022-00294-4
Autor:
Lina Jonsson, Elin Hörbeck, Erik Smedler, Robert Karlsson, Jie Song, Timea Sparding, Erik Pålsson, Mikael Landen
Publikováno v:
European Neuropsychopharmacology. 63:e181-e182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6600cfeec240794908966254033308c6
https://doi.org/10.1016/j.euroneuro.2022.07.328
https://doi.org/10.1016/j.euroneuro.2022.07.328
Publikováno v:
Acta Psychiatrica Scandinavica. 141:534-540
To investigate external factors that trigger manic and hypomanic relapses and how this is associated with personality and clinical outcome measured as number of affective episodes over a seven-year period.This is a prospective cohort study of 204 met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d11417d309ac75951270f56a5d816ff
https://doi.org/10.1111/acps.13174
https://doi.org/10.1111/acps.13174
Autor:
Erik Smedler, Lauri Louhivuori, Roman A. Romanov, Débora Masini, Ivar Dehnisch Ellström, Chungliang Wang, Martino Caramia, Zoe West, Songbai Zhang, Paola Rebellato, Seth Malmersjö, Irene Brusini, Shigeaki Kanatani, Gilberto Fisone, Tibor Harkany, Per Uhlén
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance The gene CACNA1C encodes for a calcium channel that has been linked to various psychiatric conditions, including schizophrenia and bipolar disorder, through hitherto unknown cellular mechanisms. Here, we report that deletion of Cacna1c i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f7316c4e080add65ba82a68fb915f2c
https://doi.org/10.1073/pnas.2108768119
https://doi.org/10.1073/pnas.2108768119
Autor:
Anniella Isgren, Andreas Göteson, Jessica Holmén-Larsson, Aurimantas Pelanis, Carl Sellgren, Erik Joas, Timea Sparding, Henrik Zetterberg, Erik Smedler, Joel Jakobsson, Mikael Landén
Publikováno v:
Molecular psychiatry. 27(11)
The pathophysiology of bipolar disorder remains to be elucidated and there are no diagnostic or prognostic biomarkers for the condition. In this explorative proteomic study, we analyzed 201 proteins in cerebrospinal fluid (CSF) from mood stable bipol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e947d00294dabb1cbb14cd4ae50461c
https://pubmed.ncbi.nlm.nih.gov/35986174
https://pubmed.ncbi.nlm.nih.gov/35986174
Autor:
Erik Smedler, Amedeo Primerano, Salma Mohamed, Lina Jonsson, Ian Jones, Arianna Di Florio, Mikael Landen
Publikováno v:
European Neuropsychopharmacology. 63:e109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6924b10ec3d2f79cdf826cea10f1cbe
https://doi.org/10.1016/j.euroneuro.2022.07.206
https://doi.org/10.1016/j.euroneuro.2022.07.206
Autor:
Anniella Isgren, Jessica Holmén-Larsson, Auris Pelanis, Andreas Göteson, Mikael Landén, Joel Jakobsson, Erik Smedler, Lina Jonsson, Henrik Zetterberg, Erik Pålsson, Timea Sparding
Publikováno v:
European Neuropsychopharmacology. 51:e205-e206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e20a2e1c377e543f5abf6c82d33d26a
https://doi.org/10.1016/j.euroneuro.2021.08.195
https://doi.org/10.1016/j.euroneuro.2021.08.195
Publikováno v:
Journal of neurochemistryREFERENCES. 158(3)
No robust biomarkers have yet been identified for autism spectrum disorder (ASD) or autistic traits. Familial factors likely influence biomarkers such as protein concentrations. Comparing twins with ASD or high autistic traits to the less affected co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451eaa2c2ec9a59ac6f17ed3feff03f3
https://pubmed.ncbi.nlm.nih.gov/33675537
https://pubmed.ncbi.nlm.nih.gov/33675537