Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Erik S. Leshane"'
Autor:
Anil K. Sood, Svetlana Lutsenko, Gabriel Lopez-Berestein, Zahid H. Siddik, Robert L. Coleman, Judith K. Wolf, Pablo E. Vivas-Mejia, Nicholas B. Jennings, Jeong-Won Lee, Christopher G. Danes, Alpa M. Nick, Yvonne G. Lin, Mian M.K. Shahzad, Takemi Tanaka, Whitney A. Spannuth, Guillermo N. Armaiz-Pena, Jyotsna B. Halder, Erik S. Leshane, Rosemarie Schmandt, Vesna Zuzel, Lingegowda S. Mangala
Purpose: Resistance to platinum chemotherapy remains a significant problem in ovarian carcinoma. Here, we examined the biological mechanisms and therapeutic potential of targeting a critical platinum resistance gene, ATP7B, using both in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574928cbefc6bae28a5acd99194701ef
https://doi.org/10.1158/1078-0432.c.6517644
https://doi.org/10.1158/1078-0432.c.6517644
Autor:
Anil K. Sood, Svetlana Lutsenko, Gabriel Lopez-Berestein, Zahid H. Siddik, Robert L. Coleman, Judith K. Wolf, Pablo E. Vivas-Mejia, Nicholas B. Jennings, Jeong-Won Lee, Christopher G. Danes, Alpa M. Nick, Yvonne G. Lin, Mian M.K. Shahzad, Takemi Tanaka, Whitney A. Spannuth, Guillermo N. Armaiz-Pena, Jyotsna B. Halder, Erik S. Leshane, Rosemarie Schmandt, Vesna Zuzel, Lingegowda S. Mangala
Supplementary Data from Therapeutic Targeting of ATP7B in Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ff0d02e1547a24fb9f7b22bad2beeb
https://doi.org/10.1158/1078-0432.22440294
https://doi.org/10.1158/1078-0432.22440294
Autor:
Judith K. Wolf, Pablo E. Vivas-Mejia, Jeong-Won Lee, Mian M.K. Shahzad, Zahid H. Siddik, Guillermo N. Armaiz-Pena, Lingegowda S. Mangala, Christopher G. Danes, Vesna Zuzel, Nicholas B. Jennings, Robert L. Coleman, Gabriel Lopez-Berestein, Rosemarie Schmandt, Yvonne G. Lin, Whitney A. Spannuth, Takemi Tanaka, Jyotsna B. Halder, Svetlana Lutsenko, Alpa M. Nick, Anil K. Sood, Erik S. Leshane
Publikováno v:
Clinical Cancer Research. 27:4454-4454
Autor:
Martina Ralle, Erik S. Leshane, Joel M. Walker, Amanda N. Barry, Ninian J. Blackburn, Ujwal Shinde, Svetlana Lutsenko
Publikováno v:
Journal of Biological Chemistry. 285:6327-6336
Copper-transporting ATPase ATP7B is essential for human copper homeostasis and normal liver function. ATP7B has six N-terminal metal-binding domains (MBDs) that sense cytosolic copper levels and regulate ATP7B. The mechanism of copper sensing and sig
Autor:
Nicholas B. Jennings, Jyotsna B. Halder, Takemi Tanaka, Vesna Zuzel, Mian M.K. Shahzad, Robert L. Coleman, Whitney A. Spannuth, Rosemarie Schmandt, Guillermo N. Armaiz-Pena, Judith K. Wolf, Yvonne G. Lin, Pablo E. Vivas-Mejia, Zahid H. Siddik, Erik S. Leshane, Christopher G. Danes, Gabriel Lopez-Berestein, Svetlana Lutsenko, Jeong Won Lee, Alpa M. Nick, Lingegowda S. Mangala, Anil K. Sood
Publikováno v:
Clinical Cancer Research. 15:3770-3780
Purpose: Resistance to platinum chemotherapy remains a significant problem in ovarian carcinoma. Here, we examined the biological mechanisms and therapeutic potential of targeting a critical platinum resistance gene, ATP7B, using both in vitro and in
Autor:
Erik S. LeShane, Diana W. Bianchi, Lynn Borgatta, Kirby L. Johnson, Tuangsit Wataganara, Inga Peter, Angela Y. Chen, Lisa M. Sullivan
Publikováno v:
Annals of the New York Academy of Sciences. 1022:129-134
Analysis of cell-free fetal DNA (fDNA) and RNA in maternal plasma could be useful in the diagnosis and management of complications of pregnancy. In this review, we discuss our studies to investigate the potential of fetal nucleic acid measurement in
Publikováno v:
American Journal of Obstetrics and Gynecology. 190:1087-1090
Objective The purpose of this study was to determine whether cell-free fetal DNA is detectable in the cerebrospinal fluid of women during pregnancy and after delivery. Study design Cerebrospinal fluid was collected from 39 women who underwent an indi
Autor:
Diana W. Bianchi, Dianne X. Dang, Wolfgang Holzgreve, Kirby L. Johnson, Sinuhe Hahn, William Weber, Lisa M. Hire, Kimberly A. Dukes, Sherman Elias, John Vidaver, Arun K. Sharma, Farideh Z. Bischoff, Katherine W. Klinger, Joe Leigh Simpson, Erik S. LeShane, Idania Ramirez
Publikováno v:
Clinical Chemistry. 50:516-521
Background: Analysis of fetal DNA from maternal plasma by PCR offers great potential for noninvasive prenatal genetic diagnosis. To further evaluate this potential, we developed and validated a standard protocol to determine whether fetal DNA sequenc
Autor:
Erik S. LeShane, Diana W. Bianchi, Thomas Lee, Jacob A. Canick, Walter W. Heber, Antonio Farina, Geralyn Messerlian
Publikováno v:
American Journal of Obstetrics and Gynecology. 187:1217-1221
Increased levels of cell-free fetal DNA (f-DNA) in the maternal circulation are a potential noninvasive marker for fetal Down syndrome. Our objectives were to (1) determine whether f-DNA could be quantified by using archived serum and amniotic fluid,
Publikováno v:
Fetal Diagnosis and Therapy. 17:83-89
Objective: We conducted a trial to test if the blood of pregnant women contains fetal clonogenic erythroid cells the progeny of which can be identified and isolated by a newly developed flow-sorting procedure. Methods: We have previously demonstrated