Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Erik Södersten"'
Autor:
Alexandra J. Zimmer, Samuel G. Schumacher, Erik Södersten, Anna Mantsoki, Romain Wyss, David H. Persing, Sara Banderby, Linda Strömqvist Meuzelaar, Jacqueline Prieto, Devasena Gnanashanmugam, Purvesh Khatri, Stefano Ongarello, Morten Ruhwald, Claudia M. Denkinger
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract Objectives A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA sequencing platforms. The signature was recently translated by Cepheid i
Externí odkaz:
https://doaj.org/article/38d04284727c4d5c96a54ab1892ae1dc
Autor:
Flora Martinez Figueira Moreira, Renu Verma, Paulo Cesar Pereira dos Santos, Alessandra Leite, Andrea da Silva Santos, Rafaele Carla Pivetta de Araujo, Bruna Oliveira da Silva, Júlio Henrique Ferreira de Sá Queiroz, David H. Persing, Erik Södersten, Devasena Gnanashanmugam, Purvesh Khatri, Julio Croda, Jason R. Andrews
Publikováno v:
EClinicalMedicine, Vol 33, Iss , Pp 100776- (2021)
Background: There is a need to identify scalable tuberculosis screening strategies among high burden populations. The WHO has identified a non-sputum-based triage test as a development priority. Methods: We performed a diagnostic case-control study o
Externí odkaz:
https://doaj.org/article/3026eadc3c9f43a7a19eb53360850caa
Autor:
Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K. Björklund, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The limited size of some neuronal types and their entangled environment renders it difficult to study their transcription regulation. Here the authors present a comparative analysis of histone modifications and transcription in dopaminergic and serot
Externí odkaz:
https://doaj.org/article/6df7c45a61984546bf5cda6b2f25f8ed
Autor:
Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K. Björklund, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the originally published version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include support to Thomas Perlmann provided by Knut and Alice Wallenberg Foundation
Externí odkaz:
https://doaj.org/article/89cfe751352c4056992547d84031ebc5
Autor:
Erik Södersten, Michael Feyder, Mads Lerdrup, Ana-Luisa Gomes, Hanna Kryh, Giada Spigolon, Jocelyne Caboche, Gilberto Fisone, Klaus Hansen
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004574 (2014)
Polycomb group (PcG) proteins bind to and repress genes in embryonic stem cells through lineage commitment to the terminal differentiated state. PcG repressed genes are commonly characterized by the presence of the epigenetic histone mark H3K27me3, c
Externí odkaz:
https://doaj.org/article/4ca99195eea0416ba9454d2441a1bfc1
Autor:
Johan Lundberg, Erik Södersten, Erik Sundström, Katarina Le Blanc, Tommy Andersson, Ola Hermanson, Staffan Holmin M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Stem cell transplantation procedures using intraparenchymal injections cause tissue injury in addition to associated surgical risks. Intravenous cell administration give engraftment in parenchymal lesions although the method has low efficacy and spec
Externí odkaz:
https://doaj.org/article/63f210d5d01845dd88b8d1297df22847
Autor:
Nikolaj Dietrich, Mads Lerdrup, Eskild Landt, Shuchi Agrawal-Singh, Mads Bak, Niels Tommerup, Juri Rappsilber, Erik Södersten, Klaus Hansen
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002494 (2012)
Polycomb Repressive Complex (PRC) 1 and PRC2 regulate genes involved in differentiation and development. However, the mechanism for how PRC1 and PRC2 are recruited to genes in mammalian cells is unclear. Here we present evidence for an interaction be
Externí odkaz:
https://doaj.org/article/43f15fa15f9f40d6bb8672c828f50123
Autor:
Konstantinos Toskas, Behzad Yaghmaeian-Salmani, Olga Skiteva, Wojciech Paslawski, Linda Gillberg, Vasiliki Skara, Irene Antoniou, Erik Södersten, Per Svenningsson, Karima Chergui, Markus Ringnér, Thomas Perlmann, Johan Holmberg
Publikováno v:
Science advances. 8(34)
How neurons in the CNS can maintain cellular identity over an entire lifespan remains largely unknown. Here we show that long-term maintenance of identity in differentiated dopaminergic and serotonergic neurons is critically reliant on the Polycomb r
Autor:
Renu Verma, Flora Martinez Figueira Moreira, Jason R. Andrews, David H. Persing, Andrea da Silva Santos, Júlio Henrique Ferreira de Sá Queiroz, Purvesh Khatri, Erik Södersten, Julio Croda, Alessandra Leite, Rafaele Carla Pivetta de Araujo, Bruna Oliveira da Silva, Devasena Gnanashanmugam, Paulo César Pereira dos Santos
Publikováno v:
EClinicalMedicine
EClinicalMedicine, Vol 33, Iss, Pp 100776-(2021)
EClinicalMedicine, Vol 33, Iss, Pp 100776-(2021)
BackgroundThere is a need to identify scalable tuberculosis screening strategies among high burden populations. The WHO has identified a non-sputum-based triage test as a development priority.MethodsWe performed a diagnostic case-control study of poi
Autor:
Samuel G Schumacher, Devasena Gnanashanmugam, Erik Södersten, Linda Strömqvist Meuzelaar, Jacqueline Prieto, Anna Mantsoki, Purvesh Khatri, David H. Persing, Claudia M. Denkinger, Romain Wyss, Stefano Ongarello, Sara Banderby
Publikováno v:
Journal of Clinical Microbiology
A nonsputum triage test to rule out tuberculosis (TB) disease is a WHO high-priority diagnostic, and a combinatory score based on a 3-gene host signature has shown promise in discriminating TB from other illnesses. We evaluated the accuracy of an ear