Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Erik N. Meyers"'
Autor:
Alexandra Petiet, Erik N. Meyers, Silvia Rho, G. Allan Johnson, John Klingensmith, Chandra L. Davenport, Matthew M. Goddeeris
Publikováno v:
Development. 135:1887-1895
Septation of the mammalian heart into four chambers requires the orchestration of multiple tissue progenitors. Abnormalities in this process can result in potentially fatal atrioventricular septation defects (AVSD). The contribution of extracardiac c
Publikováno v:
Development. 134:1593-1604
Cardiac outflow tract (OFT) septation is crucial to the formation of the aortic and pulmonary arteries. Defects in the formation of the OFT can result in serious congenital heart defects. Two cell populations, the anterior heart field (AHF) and cardi
Publikováno v:
Circulation Research. 100:220-228
Bone morphogenetic proteins (BMPs) play many roles in mammalian cardiac development. Here we address the functions of Noggin, a dedicated BMP antagonist, in the developing mouse heart. In early cardiac tissues, the Noggin gene is mainly expressed in
Autor:
Erik N. Meyers, Yu-Ping Yang, Robert J. Schwartz, Roger M. Ilagan, Radwan Abu-Issa, Doris Brown, John Klingensmith, Kai Jiao
Publikováno v:
Development. 133:2435-2445
In the mouse embryo, the splanchnic mesodermal cells of the anterior heart field (AHF) migrate from the pharynx to contribute to the early myocardium of the outflow tract (OT) and right ventricle (RV). Recent studies have attempted to distinguish the
Autor:
Doris Herzlinger, Cristina Cebrián, Erik N. Meyers, Uta Grieshammer, Gail R. Martin, Roger M. Ilagan
Publikováno v:
Development. 132:3847-3857
During kidney morphogenesis, the formation of nephrons begins when mesenchymal nephron progenitor cells aggregate and transform into epithelial vesicles that elongate and assume an S-shape. Cells in different regions of the S-shaped body subsequently
Autor:
Noah A. Byrd, Erik N. Meyers
Publikováno v:
Developmental Biology. 284(1):233-245
Several syndromes characterized by defects in cardiovascular and craniofacial development are associated with a hemizygous deletion of chromosome 22q11 in humans and involve defects in pharyngeal arch and neural crest cell development. Recent efforts
Autor:
Erik N. Meyers, Ryan M. Anderson, Ken Ichi Yamamura, Radwan Abu-Issa, I. Washington Smoak, John Klingensmith, Noah A. Byrd, J. Morris, Matthew M. Goddeeris
Publikováno v:
Developmental Biology. 283(2):357-372
The Hedgehog signaling pathway is critical for a significant number of developmental patterning events. In this study, we focus on the defects in pharyngeal arch and cardiovascular patterning present in Sonic hedgehog (Shh) null mouse embryos. Our da
Autor:
Erik N. Meyers, Perry J. Blackshear, Robert R. Maronpot, Trisha Castranio, Ruth S. Phillips, Noah A. Byrd, Sanjukta Ghosh, Yuji Mishina, Deborah J. Stumpo
Publikováno v:
Molecular and Cellular Biology. 24:6445-6455
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich elements within the 3'-untranslated regions of the mRNAs encoding tumor necro
Publikováno v:
Development. 131:2205-2218
The neural crest is a multipotent, migratory cell population arising from the border of the neural and surface ectoderm. In mouse, the initial migratory neural crest cells occur at the five-somite stage. Bone morphogenetic proteins(BMPs), particularl
Publikováno v:
Genes & Development. 13:1834-1846
Fgf8 and Fgf4 encode FGF family members that are coexpressed in the primitive streak of the gastrulating mouse embryo. We have analyzed the phenotype of Fgf8(-/-) embryos and discovered that they fail to express Fgf4 in the streak. In the absence of