Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Erik M. Whiteley"'
Autor:
Francisco J. Castillo, Georg Roth, Susan Harvey, Erik M. Whiteley, Tana Montgomery, Jenifer L. Ayala, Thomas J. Monica, John J. Garbutt, Gary M. Schoofs
Publikováno v:
Biotechnology Progress. 16:866-871
Several known process monitoring methods were tested for their efficacy in the detection of adenovirus infections. The methods that we explored include several indirect indications of viral infections, including metabolic rate analysis, secondary gau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b72470efc9b6b71a1c2e538dce7bcf8
https://doi.org/10.1021/bp000084f
https://doi.org/10.1021/bp000084f
Publikováno v:
Journal of Biological Chemistry. 274:17551-17558
The serotonin transporter (SERT) is an N-glycosylated integral membrane protein that is predicted to contain 12 transmembrane regions. SERT is the major binding site in the brain for antidepressant drugs, and it also binds amphetamines and cocaine. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcc08ba8fb2d9dd925383e6ea662506
https://doi.org/10.1074/jbc.274.25.17551
https://doi.org/10.1074/jbc.274.25.17551
Publikováno v:
Biotechnology and Bioengineering. 56:106-116
A model for immunoglobulin G (IgG) production in the baculovirus-insect cell system was developed that incorporates polypeptide synthesis, oligomer assembly, protein aggregation, and protein secretion. In addition, the capacity of a chaperone to prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccdb9d6ef81201f8f3ebcea080d7c106
https://doi.org/10.1002/(sici)1097-0290(19971005)56:1<106::aid-bit12>3.0.co
https://doi.org/10.1002/(sici)1097-0290(19971005)56:1<106::aid-bit12>3.0.co
Publikováno v:
Journal of Biological Chemistry. 272:22556-22563
Coexpression of the enzyme, protein disulfide isomerase (PDI), has been shown to increase soluble and secreted IgG levels from baculovirus-infected insect cells (Hsu, T.-A., Watson, S., Eiden, J. J., and Betenbaugh, M. J. (1996) Protein Expression Pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b405c77c9c5b57c36ec028c0bca314bc
https://doi.org/10.1074/jbc.272.36.22556
https://doi.org/10.1074/jbc.272.36.22556
Autor:
Noriko Takahashi, Tsu-An Hsu, Yuan C. Lee, Erik M. Whiteley, Michael J. Betenbaugh, Yoshinori Tsukamoto, Koichi Kato, Katsuyoshi Masuda, Jian-Qiang Fan, Ichio Shimada
Publikováno v:
Journal of Biological Chemistry. 272:9062-9070
Structures of the N-linked oligosaccharide attached to the heavy chain of a heterologous murine IgG2a produced from Trichoplusia ni (TN-5B1-4, High Five) insect cells were characterized. Coexpression of the chaperone immunoglobulin heavy chain-bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130ce60e37ae0dbbf83adde5a0005e74
https://doi.org/10.1074/jbc.272.14.9062
https://doi.org/10.1074/jbc.272.14.9062
Publikováno v:
Cytotechnology. 20(1-3)
The BEVS has become widely utilized for production of recombinant proteins. However, protein aggregation and inefficient processing often limit yields, especially for secreted and membrane proteins. Since many proteins of pharmaceutical interest requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba39739f0f7fc495bb3ae9cf229c36e8
https://pubmed.ncbi.nlm.nih.gov/22358480
https://pubmed.ncbi.nlm.nih.gov/22358480
Publikováno v:
Encyclopedia of Industrial Biotechnology
The use of the insect cell-baculovirus system has grown significantly over the past three decades. The present chapter elucidates the fundamentals, scientific developments, technologies, and hurdles encountered in this field. The common types of inse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f65841c166eacb1c529a047e6a4e9d
https://doi.org/10.1002/9780470054581.eib371
https://doi.org/10.1002/9780470054581.eib371
Autor:
Francisco J. Castillo, Michael Mccaman, Jacob Kung, Elisabeth Lehmberg, Erno Pungor, Erik M. Whiteley, Yasushi Ogawa, Bruce Mann, Farah Fawaz, Mei Tan, Gabor M. Rubanyi
Publikováno v:
Modern Biopharmaceuticals: Design, Development and Optimization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b925ddda2a50d892ccc2ecb2427133
https://doi.org/10.1002/9783527620982.ch6
https://doi.org/10.1002/9783527620982.ch6
Publikováno v:
Encyclopedia of Cell Technology
Introduction The Protein Processing Assembly Line Polypeptide Production The Endoplasmic Reticulum: Polypeptide Folding and Modification Overview of the ER Lumen Folding in the ER Glycosylation in the ER Glycosylphosphatidylinositol-Linked Proteins M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed4a38ca6c234cea6becf6b28646db1
https://doi.org/10.1002/0471250570.spi095
https://doi.org/10.1002/0471250570.spi095