Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Erik M. Quandt"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007348 (2018)
Key innovations are disruptive evolutionary events that enable a species to escape constraints and rapidly diversify. After 15 years of the Lenski long-term evolution experiment with Escherichia coli, cells in one of the twelve populations evolved th
Externí odkaz:
https://doaj.org/article/8ef42b3361914b5884d579a1aa1f8f93
Publikováno v:
PeerJ, Vol 6, p e4286 (2018)
The maintenance of a G + C content that is higher than the mutational input to a genome provides support for the view that selection serves to increase G + C contents in bacteria. Recent experimental evidence from Escherichia coli demonstrated that s
Externí odkaz:
https://doaj.org/article/b081f547f0e84dc9810ffc68b27deb39
Autor:
Peter J Enyeart, Steven M Chirieleison, Mai N Dao, Jiri Perutka, Erik M Quandt, Jun Yao, Jacob T Whitt, Adrian T Keatinge‐Clay, Alan M Lambowitz, Andrew D Ellington
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-16 (2013)
Abstract Efficient bacterial genetic engineering approaches with broad‐host applicability are rare. We combine two systems, mobile group II introns (‘targetrons’) and Cre/lox, which function efficiently in many different organisms, into a versa
Externí odkaz:
https://doaj.org/article/a6684a167997479bb650e58ad13f1786
Autor:
Erik M Quandt, Jimmy Gollihar, Zachary D Blount, Andrew D Ellington, George Georgiou, Jeffrey E Barrick
Publikováno v:
eLife, Vol 4 (2015)
Evolutionary innovations that enable organisms to colonize new ecological niches are rare compared to gradual evolutionary changes in existing traits. We discovered that key mutations in the gltA gene, which encodes citrate synthase (CS), occurred bo
Externí odkaz:
https://doaj.org/article/69491e02ef3e4d1dbfe1f2d95bcab344
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007348 (2018)
PLoS Genetics
PLoS Genetics
Key innovations are disruptive evolutionary events that enable a species to escape constraints and rapidly diversify. After 15 years of the Lenski long-term evolution experiment with Escherichia coli, cells in one of the twelve populations evolved th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c421c04df2c81654a3dc3504155ecb27
http://europepmc.org/articles/PMC5918244?pdf=render
http://europepmc.org/articles/PMC5918244?pdf=render
After 15 years of the Lenski experiment one of twelveEscherichia colipopulations evolved the ability to utilize an abundant but previously untapped carbon source, citrate. Mutations responsible for the appearance of rudimentary citrate utilization (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcea094fca8d1ddbfecb936e103b4a2c
https://doi.org/10.1101/249110
https://doi.org/10.1101/249110
Autor:
Constantine Chrysostomou, Everett Stone, Nicholas M. Marshall, George Georgiou, Erik M. Quandt
Publikováno v:
ACS Chemical Biology
Microbial arsenate resistance is known to be conferred by specialized oxidoreductase enzymes termed arsenate reductases. We carried out a genetic selection on media supplemented with sodium arsenate for multicopy genes that can confer growth to E. co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1953f08693df51b01a926050a3b050
https://doi.org/10.1021/cb500755j
https://doi.org/10.1021/cb500755j
The maintenance of a G+C content that is higher than the mutational input to a genome supports the view that selection serves to increase G+C contents in many bacteria. Recent experimental evidence from Escherichia coli has demonstrated that selectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede3d53591dfed700ceef782de167213
https://doi.org/10.7287/peerj.preprints.3011v1
https://doi.org/10.7287/peerj.preprints.3011v1
Autor:
George Georgiou, Daniel E. Deatherage, Erik M. Quandt, Jeffrey E. Barrick, Andrew D. Ellington
Publikováno v:
Proceedings of the National Academy of Sciences. 111:2217-2222
Evolutionary innovations often arise from complex genetic and ecological interactions, which can make it challenging to understand retrospectively how a novel trait arose. In a long-term experiment, Escherichia coli gained the ability to use abundant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1680c4a1c3e0722eac080f0a66b5b1
https://doi.org/10.1073/pnas.1314561111
https://doi.org/10.1073/pnas.1314561111
Publikováno v:
How Evolution Shapes Our Lives: Essays on Biology and Society
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113054482198ed57465dd0d8818e1898
https://doi.org/10.1515/9781400881383-015
https://doi.org/10.1515/9781400881383-015