Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Erik M. Kolb"'
Publikováno v:
Behavioural Processes. 146:46-53
To explore reward substitution in the context of voluntary exercise, female mice from four replicate high-runner (HR) lines (bred for wheel running) and four non-selected control (C) lines were given simultaneous access to wheels and palatable soluti
Publikováno v:
Journal of Experimental Biology.
Chronic voluntary exercise elevates total daily energy expenditure and food consumption, potentially resulting in organ compensation supporting nutrient extraction/utilization. Additionally, species with naturally higher daily energy expenditure ofte
Autor:
Theodore Garland, Jessica L. Malisch, Brooke K. Keeney, Scott A. Kelly, Kevin M. Middleton, Erik M. Kolb, Robert Hannon, Shana L. Van Cleave
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences. 278:574-581
The response to uniform selection may occur in alternate ways that result in similar performance. We tested for multiple adaptive solutions during artificial selection for high voluntary wheel running in laboratory mice. At generation 43, the four re
Autor:
L S Sermsakdi, Kevin M. Middleton, Theodore Garland, Scott A. Kelly, Erik M. Kolb, Mark A. Chappell
Publikováno v:
Journal of Experimental Biology. 213:510-519
SUMMARYVoluntary activity is a complex trait, comprising both behavioral (motivation, reward) and anatomical/physiological (ability) elements. In the present study, oxygen transport was investigated as a possible limitation to further increases in ru
Autor:
Robert Hannon, Scott A. Kelly, Kevin M. Middleton, Daniel Pomp, Erik M. Kolb, Theodore Garland
Publikováno v:
Journal of Heredity. 99:349-354
From outbred Hsd:ICR mice, we selectively bred 4 replicate lines for high running (High-Runner [HR] lines) on wheels while maintaining 4 nonselected lines as controls (C lines). An apparent Mendelian recessive, the "mini-muscle" (MM) allele, whose ma
Autor:
Scott A, Kelly, Enrico L, Rezende, Mark A, Chappell, Fernando R, Gomes, Erik M, Kolb, Jessica L, Malisch, Justin S, Rhodes, Gordon S, Mitchell, Theodore, Garland
Publikováno v:
Experimental physiology. 99(2)
What is the central question of this study? We used experimental evolution to determine how selective breeding for high voluntary wheel running and exercise training (7-11 weeks) affect ventilatory chemoreflexes of laboratory mice at rest. What is th
Autor:
Enrico L. Rezende, Sun K. Lee, Andre Obenaus, A. Radtke, Theodore Garland, Erik M. Kolb, L. Holness
Publikováno v:
The Journal of experimental biology. 216(Pt 3)
Increased brain size, relative to body mass, is a primary characteristic distinguishing the mammalian lineage. This greater encephalization has come with increased behavioral complexity and, accordingly, it has been suggested that selection on behavi
Publikováno v:
Physiologybehavior.
► Exercise is rewarding and has positive effects on mental and physical health. ► Excessive exercise may sometimes reflect an underlying addiction. ► We studied lines of mice selectively bred for high voluntary wheel running (HR). ► During wi
Autor:
Sumeer Thinda, Erik M. Kolb, Wesley R. Matsumoto, Alexis L. Higgins, Shahen Ahmed, Wendy Saltzman, Laura McGeehan
Publikováno v:
Developmental psychobiology. 51(1)
Mongolian gerbils living with their natal families undergo delayed reproductive maturation while helping to rear their younger siblings, whereas those housed away from their natal families may mature earlier but often respond aggressively to unfamili
Autor:
Robert Hannon, Theodore Garland, Haruka Wada, Erik M. Kolb, Kevin M. Middleton, Jessica L. Malisch, Creagh W. Breuner, Mark A. Chappell
Publikováno v:
Behavior genetics. 39(2)
Dysfunction of the hypothalamic-pituitary-adrenal axis resulting in elevated baseline glucocorticoid concentrations is a hallmark of stress-related human anxiety and affective disorders, including depression. Mice from four replicate lines bred for h