Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Erik L. de Graaf"'
Autor:
Donna O. Debets, Erik L. de Graaf, Marte C. Liefaard, Gabe S. Sonke, Esther H. Lips, Anna Ressa, Maarten Altelaar
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109858- (2024)
Summary: In this study, we measured the kinase activity profiles of 32 pre-treatment tumor biopsies of HER2-positive breast cancer patients. The aim of this study was to assess the prognostic potential of kinase activity levels, to identify potential
Externí odkaz:
https://doaj.org/article/bfdbc26b61c74528a8ee376a35d970f6
Autor:
Zoltán Szittner, Arthur E. H. Bentlage, A. Robin Temming, David E. Schmidt, Remco Visser, Suzanne Lissenberg-Thunnissen, Juk Yee Mok, Wim J. E. van Esch, Myrthe E. Sonneveld, Erik L. de Graaf, Manfred Wuhrer, Leendert Porcelijn, Masja de Haas, C. Ellen van der Schoot, Gestur Vidarsson
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) can occur due to maternal IgG antibodies targeting platelet antigens, causing life-threatening bleeding in the neonate. However, the disease manifests itself in only a fraction of pregnancies, mo
Externí odkaz:
https://doaj.org/article/91e5bf2c71b7454b8cb27f5857ceb701
Autor:
Federica Fabro, Nynke M. Kannegieter, Erik L. de Graaf, Karla Queiroz, Martine L. M. Lamfers, Anna Ressa, Sieger Leenstra
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastoma is the deadliest brain cancer. One of the main reasons for poor outcome resides in therapy resistance, which adds additional challenges in finding an effective treatment. Small protein kinase inhibitors are molecules that have become wid
Externí odkaz:
https://doaj.org/article/a03d0dd0ba92489c833fc6b7a77ba8fd
Autor:
Donna O. Debets, Erik L. de Graaf, Marte C. Liefaard, Gabe S. Sonke, Esther H. Lips, Anna Ressa, Maarten Altelaar
In this study, we measured the kinase activity profiles of 32 pre-treatment tumour biopsies of HER2-positive breast cancer patients. The aim of this study was to assess the prognostic potential of kinase activity levels to identify potential mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb2afc7fcb3d14029024c667c1b9dc5
https://doi.org/10.1101/2022.09.23.508980
https://doi.org/10.1101/2022.09.23.508980
Autor:
Erik L. de Graaf, Thomas Sénard, Yassene Mohammed, Peter A. van Veelen, Manfred Wuhrer, David Falck, Arnoud H. de Ru, Iwona Wojcik, George M.C. Janssen, Gestur Vidarsson
Publikováno v:
Analytical chemistry, 92(19), 13172-13181. American Chemical Society
Analytical Chemistry
Analytical Chemistry, 92(19), 13172-13181. AMER CHEMICAL SOC
Analytical Chemistry
Analytical Chemistry, 92(19), 13172-13181. AMER CHEMICAL SOC
Fc gamma receptors (Fc gamma Rs) translate antigen recognition by immunoglobulin G (IgG) into various immune responses. A better understanding of this key element of immunity promises novel insights into mechanisms of (auto-/allo-)immune diseases and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735d75ed763479a4c057299f5f2eabec
https://pure.amc.nl/en/publications/sitespecific-glycosylation-mapping-of-fc-gamma-receptor-iiib-from-neutrophils-of-individual-healthy-donors(91eacf40-e940-4555-96c6-53f76958ebc4).html
https://pure.amc.nl/en/publications/sitespecific-glycosylation-mapping-of-fc-gamma-receptor-iiib-from-neutrophils-of-individual-healthy-donors(91eacf40-e940-4555-96c6-53f76958ebc4).html
Autor:
Federica Linty, Steven W. deTaeye, C. Ellen van der Schoot, Carolien A. M. Koeleman, Suvi Natunen, Alexander P.J. Vlaar, H. Rosina Plomp, Susanna Sainio, Myrthe E. Sonneveld, Maximilian Brinkhaus, Mads Delbo Larsen, Marit J. van Gils, Philip J. M. Brouwer, Jan Nouta, Neeltje A. Kootstra, Manfred Wuhrer, Hans L. Zaaijer, Rogier W. Sanders, Erik L. de Graaf, Gestur Vidarsson, Sanne de Bruin, Arthur E. H. Bentlage, Tonci Sustic, Remco Visser
IgG antibodies are crucial for protection against invading pathogens. A highly conserved N-linked glycan within the IgG-Fc-tail, essential for IgG function, shows variable composition in humans. Afucosylated IgG variants are already used in anti-canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e83e51cfdb03bc8368f6c27a72855c
https://doi.org/10.1101/2020.05.18.099507
https://doi.org/10.1101/2020.05.18.099507
Autor:
George M.C. Janssen, Yassene Mohammed, Peter A. van Veelen, Manfred Wuhrer, David Falck, Erik L. de Graaf, Gestur Vidarsson, Arnoud H. de Ru, Iwona Wojcik, Thomas Sénard
Publikováno v:
bioRxiv
Fc gamma receptors (FcγR) translate antigen-recognition by immunoglobulin G (IgG) into various immune responses. A better understanding of this key element of immunity promises novel insights into mechanisms of (auto-/allo-)immune diseases and more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfd959a72c50d348278a36524ae8b88
Autor:
Gillian Dekkers, Sietse Q. Nagelkerke, James C. Zimring, Peter C. Ligthart, Louise A. de Neef, Manfred Wuhrer, Jana Koers, Christine W. Bruggeman, Erik L. de Graaf, Theo Rispens, Taco W. Kuijpers, Gestur Vidarsson, A. Robin Temming, Steven W. de Taeye
Publikováno v:
Journal of Immunology, 203(12), 3126-3135
Journal of immunology (Baltimore, Md., 203(12), 3126-3135. American Association of Immunologists
Journal of immunology (Baltimore, Md., 203(12), 3126-3135. American Association of Immunologists
Ab-dependent cellular cytotoxicity (ADCC) is one of the most important effector mechanisms of tumor-targeting Abs in current immunotherapies. In ADCC and other Ab-dependent activation of myeloid effector cells, close cell–cell contact (between effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8530629ee5fb74a4d4b1897ff701ba8b
http://hdl.handle.net/1887/121321
http://hdl.handle.net/1887/121321
Autor:
Francesco Olimpico, Silvia Middei, Matteo Caleo, Laura Baroncelli, Gudula Schmidt, Liam A. McDonnell, Martine Ammassari-Teule, Mario Costa, Alessia Fabbri, Carla Fiorentini, Erik L. de Graaf, Eleonora Vannini
Publikováno v:
Journal of neuro-oncology 18 (2016): 1634–1643. doi:10.1093/neuonc/now114
info:cnr-pdr/source/autori:Vannini, E.; Olimpico, F.; Middei, S.; Ammassari-Teule, M.; de Graaf, EL.; McDonnell, L.; Schmidt, G.; Fabbri, A.; Fiorentini, C.; Baroncelli, L.; Costa, M.; Caleo, M./titolo:Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function/doi:10.1093%2Fneuonc%2Fnow114/rivista:Journal of neuro-oncology/anno:2016/pagina_da:1634/pagina_a:1643/intervallo_pagine:1634–1643/volume:18
Europe PubMed Central
info:cnr-pdr/source/autori:Vannini, E.; Olimpico, F.; Middei, S.; Ammassari-Teule, M.; de Graaf, EL.; McDonnell, L.; Schmidt, G.; Fabbri, A.; Fiorentini, C.; Baroncelli, L.; Costa, M.; Caleo, M./titolo:Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function/doi:10.1093%2Fneuonc%2Fnow114/rivista:Journal of neuro-oncology/anno:2016/pagina_da:1634/pagina_a:1643/intervallo_pagine:1634–1643/volume:18
Europe PubMed Central
Background Glioblastomas are the most aggressive type of brain tumor. A successful treatment should aim at halting tumor growth and protecting neuronal cells to prevent functional deficits and cognitive deterioration. Here, we exploited a Rho GTPase-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01946fab1685c4dce2055bd018c0c00b
https://doi.org/10.1093/neuonc/now114
https://doi.org/10.1093/neuonc/now114
Publikováno v:
Journal of proteome research. 18(1)
The identification of molecular ions produced by MALDI or ESI strongly relies on their fragmentation to structurally informative fragments. The widely diffused fragmentation techniques for ESI multiply charged ions are either incompatible (ECD and ET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924b806b802844b426daa62f70c6d3bc
https://pubmed.ncbi.nlm.nih.gov/30484663
https://pubmed.ncbi.nlm.nih.gov/30484663