Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Erik L. Clarke"'
Autor:
Erik L. Clarke, Louis J. Taylor, Chunyu Zhao, Andrew Connell, Jung-Jin Lee, Bryton Fett, Frederic D. Bushman, Kyle Bittinger
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Analysis of mixed microbial communities using metagenomic sequencing experiments requires multiple preprocessing and analytical steps to interpret the microbial and genetic composition of samples. Analytical steps include quality
Externí odkaz:
https://doaj.org/article/56cc1c964e0d4947b4e19e5831d07f81
Autor:
Jacob S. Leiby, Kevin McCormick, Scott Sherrill-Mix, Erik L. Clarke, Lyanna R. Kessler, Louis J. Taylor, Casey E. Hofstaedter, Aoife M. Roche, Lisa M. Mattei, Kyle Bittinger, Michal A. Elovitz, Rita Leite, Samuel Parry, Frederic D. Bushman
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background Historically, the human womb has been thought to be sterile in healthy pregnancies, but this idea has been challenged by recent studies using DNA sequence-based methods, which have suggested that the womb is colonized with bacteri
Externí odkaz:
https://doaj.org/article/d37a4e8a24cc40d3bb35b803f70ebf7c
Autor:
Erik L. Clarke, A. Jesse Connell, Emmanuelle Six, Nadia A. Kadry, Arwa A. Abbas, Young Hwang, John K. Everett, Casey E. Hofstaedter, Rebecca Marsh, Myriam Armant, Judith Kelsen, Luigi D. Notarangelo, Ronald G. Collman, Salima Hacein-Bey-Abina, Donald B. Kohn, Marina Cavazzana, Alain Fischer, David A. Williams, Sung-Yun Pai, Frederic D. Bushman
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background Mutation of the IL2RG gene results in a form of severe combined immune deficiency (SCID-X1), which has been treated successfully with hematopoietic stem cell gene therapy. SCID-X1 gene therapy results in reconstitution of the prev
Externí odkaz:
https://doaj.org/article/3e61033ef32c4bfb98b5c61714518c31
Autor:
Joshua M. Taylor, Erik L. Clarke, Kate Baker, Abigail Lauder, Dorothy Kim, Aubrey Bailey, Gary D. Wu, Ronald G. Collman, Lara Doyle-Meyers, Kasi Russell-Lodrigue, James Blanchard, Frederic D. Bushman, Rudolf Bohm
Publikováno v:
PeerJ, Vol 6, p e4612 (2018)
Idiopathic chronic enterocolitis (ICE) is one of the most commonly encountered and difficult to manage diseases of captive rhesus macaques (Macaca mulatta). The etiology is not well understood, but perturbations in gut microbial communities have been
Externí odkaz:
https://doaj.org/article/7cfe6e3d6b9f4c3e84c2de0fb8b778ac
Autor:
Jerry Jacob, Arman Oganisian, Michael A. Grippi, Erik L. Clarke, James J Harrigan, Brendan J Kelly, Emily Reesey, Magda Wernovsky, Hatem O. Abdallah, Zygmunt Morawski, Ebbing Lautenbach, Jason Roy, Pam Tolomeo
Publikováno v:
Clin Infect Dis
Background Ventilator-associated lower respiratory tract infection (VA-LRTI) is common among critically ill patients and has been associated with increased morbidity and mortality. In acute critical illness, respiratory microbiome disruption indices
Autor:
Ayannah S. Fitzgerald, Hari M Shankar, Vincent R. Knecht, Kyle Bittinger, Ronald G. Collman, Ize Imai, Brendan J Kelly, Frederic D. Bushman, Erik L. Clarke, John E. McGinniss
Publikováno v:
Infect Control Hosp Epidemiol
BackgroundCulture-based studies, which focus on individual organisms, have implicated stethoscopes as potential vectors of nosocomial bacterial transmission. However, the full bacterial communities that contaminate in-use stethoscopes have not been i
Autor:
Kevin McCormick, Louis J. Taylor, Lyanna R. Kessler, Kyle Bittinger, Rita Leite, Erik L. Clarke, Michal A. Elovitz, Scott Sherrill-Mix, Casey E. Hofstaedter, Frederic D. Bushman, Samuel Parry, Jacob S. Leiby, Aoife M. Roche, Lisa M. Mattei
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-11 (2018)
Microbiome
Microbiome
Background Historically, the human womb has been thought to be sterile in healthy pregnancies, but this idea has been challenged by recent studies using DNA sequence-based methods, which have suggested that the womb is colonized with bacteria. For ex
Microbial Lineages in Sarcoidosis. A Metagenomic Analysis Tailored for Low–Microbial Content Samples
Autor:
Leslie A. Litzky, Casey E. Hofstaedter, Ayannah S. Fitzgerald, Anna Dubaniewicz, Ronald G. Collman, Michael Feldman, Wojciech Biernat, Milton D. Rossman, Erik L. Clarke, Young Hwang, Bartlomiej Rekawiecki, Karen C. Patterson, Ize Imai, Abigail Lauder, Hanna Majewska, Frederic D. Bushman, Kyle Bittinger
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 197:225-234
The etiology of sarcoidosis is unknown, but microbial agents are suspected as triggers.We sought to identify bacterial, fungal, or viral lineages in specimens from patients with sarcoidosis enriched relative to control subjects using metagenomic DNA
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology. 1:s22-s22
Background: A pathogenic group of invasive extraintestinal pathogenic (ExPEC) Escherichia coli possess the ability to infect normally sterile body sites and cause severe invasive ExPEC disease (IED). ExPEC is a leading cause of bacteremia and sepsis
Autor:
Erik L. Clarke, Edward Cantu, Hongzhe Li, Joshua M. Diamond, Ize Imai, Frederic D. Bushman, John E. McGinniss, Kyle Bittinger, Jason D. Christie, Aubrey Bailey, Ronald G. Collman, Vincent R. Knecht, M. Brown, Aurea Simon-Soro, Michael B. Sohn
Publikováno v:
Ann Am Thorac Soc
Rationale: The oropharyngeal microbiome is a primary source of lung microbiota, contributes to lower respiratory infection, and is also a driver of oral health. Objectives: We sought to understand oropharyngeal microbial communities in advanced lung