Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Erik Knutsen"'
Autor:
Erik Knutsen, Saikat Das Sajib, Tonje Fiskaa, James Lorens, Thorarinn Gudjonsson, Gunhild M. Mælandsmo, Steinar Daae Johansen, Ole-Morten Seternes, Maria Perander
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Epithelial-mesenchymal transition (EMT) is a cellular plasticity program critical for embryonic development and tissue regeneration, and aberrant EMT is associated with disease including cancer. The high degree of plasticity in the mammary epithelium
Externí odkaz:
https://doaj.org/article/0cb38a8096c34f07953bff36029fd95d
Autor:
Andreas Untergasser, Jan Hellemans, Michael W. Pfaffl, Jan M. Ruijter, Maurice J. B. van denHoff, Mihnea P. Dragomir, Douglas Adamoski, Sandra Martha Gomes Dias, Rui Manuel Reis, Manuela Ferracin, Emmanuel Dias‐Neto, Ian Marsh, Mikael Kubista, Muller Fabbri, Ajay Goel, Ondřej Slabý, Erik Knutsen, Baoqing Chen, Massimo Negrini, Koshi Mimori, Martin Pichler, Maria Papatriantafyllou, Simone Anfossi, Thomas D. Schmittgen, Jim Huggett, Stephen Bustin, Jo Vandesompele, George A. Calin, for the HEROIC (tHe initiativE gRoup On qRT dIsClosure) Consortium
Publikováno v:
Molecular Oncology, Vol 17, Iss 5, Pp 713-717 (2023)
Accuracy and transparency of scientific data are becoming more and more relevant with the increasing concern regarding the evaluation of data reproducibility in many research areas. This concern is also true for quantifying coding and noncoding RNAs,
Externí odkaz:
https://doaj.org/article/fc57157ea1114752966f2e759b70680f
Autor:
Mihnea P. Dragomir, Enrique Fuentes-Mattei, Melanie Winkle, Keishi Okubo, Recep Bayraktar, Erik Knutsen, Aiham Qdaisat, Meng Chen, Yongfeng Li, Masayoshi Shimizu, Lan Pang, Kevin Liu, Xiuping Liu, Simone Anfossi, Huanyu Zhang, Ines Koch, Anh M. Tran, Swati Mohapatra, Anh Ton, Mecit Kaplan, Matthew W. Anderson, Spencer J. Rothfuss, Robert Silasi, Ravi S. Keshari, Manuela Ferracin, Cristina Ivan, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Constantin Georgescu, Pinaki P. Banerjee, Rafet Basar, Ziyi Li, David Horst, Catalin Vasilescu, Maria Teresa S. Bertilaccio, Katayoun Rezvani, Florea Lupu, Sai-Ching Yeung, George A. Calin
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)
Sepsis remains a leading cause of death for humans and currently has no pathogenesis-specific therapy. Hampered progress is partly due to a lack of insight into deep mechanistic processes. In the past decade, deciphering the functions of small noncod
Externí odkaz:
https://doaj.org/article/d4033ceefb364ffba4d3f09a718cc569
Autor:
Marta Tellez-Gabriel, Xavier Tekpli, Trine M. Reine, Beate Hegge, Stephanie R. Nielsen, Meng Chen, Line Moi, Lisa Svartdal Normann, Lill-Tove R. Busund, George A. Calin, Gunhild M. Mælandsmo, Maria Perander, Achilleas D. Theocharis, Svein O. Kolset, Erik Knutsen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Serglycin is a proteoglycan highly expressed by immune cells, in which its functions are linked to storage, secretion, transport, and protection of chemokines, proteases, histamine, growth factors, and other bioactive molecules. In recent years, it h
Externí odkaz:
https://doaj.org/article/920c9876187840389df53c28d18f306b
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Hypercalcemia of malignancy is relatively common in several cancers. However, in colorectal cancer, paraneoplastic phenomena that cause hypercalcemia is uncommon. In the few cases that are reported, secretion of parathyroid hormon
Externí odkaz:
https://doaj.org/article/0e9c0dbcc6e946c98a5483f22042d789
Publikováno v:
Cancers, Vol 14, Iss 21, p 5328 (2022)
Proteoglycans (PGs) are pivotal components of extracellular matrices, involved in a variety of processes such as migration, invasion, morphogenesis, differentiation, drug resistance, and epithelial-to-mesenchymal transition (EMT). Cellular plasticity
Externí odkaz:
https://doaj.org/article/df4d060ee89440dc9676f58cad34810f
Autor:
Cornelia Braicu, Diana Gulei, Roxana Cojocneanu, Lajos Raduly, Ancuta Jurj, Erik Knutsen, George Adrian Calin, Ioana Berindan‐Neagoe
Publikováno v:
Molecular Oncology, Vol 13, Iss 1, Pp 9-25 (2019)
Despite substantial progress in oncology, lung cancer remains the number one malignancy in terms of both incidence and mortality rates, and there thus remains an urgent need for new therapeutic alternatives. MicroRNA (miRNA) have an important role in
Externí odkaz:
https://doaj.org/article/e6a1980b03a24cdd8b5ae2f065872b69
Autor:
Åse Emblem, Erik Knutsen, Tor Erik Jørgensen, Hilde Fure, Steinar Daae Johansen, Ole-Lars Brekke, Tom Eirik Mollnes, Bård Ove Karlsen
Publikováno v:
Non-Coding RNA, Vol 8, Iss 2, p 24 (2022)
Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat i
Externí odkaz:
https://doaj.org/article/9420d6a1f82740b2aab01409049fa63c
Autor:
Peng Shen, Lucas C. Reineke, Erik Knutsen, Meng Chen, Martin Pichler, Hui Ling, George A. Calin
Publikováno v:
Molecular Oncology, Vol 12, Iss 11, Pp 1856-1870 (2018)
The antidiabetic drug metformin has been associated with reduced colorectal cancer (CRC) risk and improved prognosis of CRC patients. However, the detailed mechanisms underlying such beneficial effects remain unknown. In this study, we aimed to evalu
Externí odkaz:
https://doaj.org/article/80c0418cb7be4da4ae481067352e5c88
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9457 (2020)
Breast cancer is the most common cancer among women worldwide. Although the five-, ten- and fifteen-year survival rates are good for breast cancer patients diagnosed with early-stage disease, some cancers recur many years after completion of primary
Externí odkaz:
https://doaj.org/article/0096aab89b0d405b8f588aecf7173c15