Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Erik Kaadt"'
Autor:
Kristoffer Højgaard, Bianka Szöllősi, Kim Henningsen, Natsumi Minami, Nobuhiro Nakanishi, Erik Kaadt, Makoto Tamura, Richard G.M. Morris, Tomonori Takeuchi, Betina Elfving
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Novelty-induced memory consolidation is a well-established phenomenon that depends on the activation of a locus coeruleus-hippocampal circuit. It is associated with the expression of activity-dependent genes that may mediate initial or cellu
Externí odkaz:
https://doaj.org/article/bff328eb54174f9ea2926bf71a0c7578
Autor:
Rebecca Best Jensen, Maria Sørensen, Jesper Just, Lee-Ann Clegg, Erik Kaadt, Rikke Bæk, Grethe Andersen, Betina Elfving, Malene Jørgensen, Rolf Blauenfeldt, Kim Drasbek
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S536-S537 (2023)
Externí odkaz:
https://doaj.org/article/0712bbb5969347848af0bbceb53b632b
Autor:
Erik Kaadt, Sidsel Alsing, Claudia R. Cecchi, Christian Kroun Damgaard, Thomas J. Corydon, Lars Aagaard
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 318-328 (2019)
The expression of short hairpin RNAs (shRNAs) may result in unwanted activity from the co-processed passenger strand. Recent studies have shown that shortening the stem of conventional shRNAs abolishes passenger strand release. These Dicer-independen
Externí odkaz:
https://doaj.org/article/67d480ae382341fea9760e2fac491c79
Autor:
Claudia R. Cecchi, Lars Aagaard, Erik Kaadt, Sidsel Alsing, Thomas J. Corydon, Christian Kroun Damgaard
Publikováno v:
Kaadt, E, Alsing, S, Cecchi, C R, Damgaard, C K, Corydon, T J & Aagaard, L 2019, ' Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds ', Molecular Therapy-Nucleic Acids, vol. 14, pp. 318-328 . https://doi.org/10.1016/j.omtn.2018.11.013
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 14, Iss, Pp 318-328 (2019)
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 14, Iss, Pp 318-328 (2019)
The expression of short hairpin RNAs (shRNAs) may result in unwanted activity from the co-processed passenger strand. Recent studies have shown that shortening the stem of conventional shRNAs abolishes passenger strand release. These Dicer-independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1fc370a457137476f1763ea265d0d7
https://pure.au.dk/portal/da/publications/efficient-knockdown-and-lack-of-passenger-strand-activity-by-dicerindependent-shrnas-expressed-from-pol-iidriven-microrna-scaffolds(e4ae4aa8-4d5a-46b2-a3cf-5de53b7b176c).html
https://pure.au.dk/portal/da/publications/efficient-knockdown-and-lack-of-passenger-strand-activity-by-dicerindependent-shrnas-expressed-from-pol-iidriven-microrna-scaffolds(e4ae4aa8-4d5a-46b2-a3cf-5de53b7b176c).html
Autor:
Erik Kaadt, Sofie Laage Christiansen, Birgitte Mumm, Kristoffer Højgaard, Heidi Kaastrup Müller, Betina Elfving, Christian Kroun Damgaard
Publikováno v:
Kaadt, E, Højgaard, K, Mumm, B, Christiansen, S L, Müller, H K, Damgaard, C K & Elfving, B 2021, ' Dysregulation of miR-185, miR-193a, and miR-450a in the skin are linked to the depressive phenotype ', Progress in Neuro-Psychopharmacology & Biological Psychiatry, vol. 104, 110052 . https://doi.org/10.1016/j.pnpbp.2020.110052
BACKGROUND: Dysregulated microRNAs (miRNAs) in dermal fibroblasts of depressive subjects, indicate biomarker potential and can possibly aid clinical diagnostics. To overcome methodological challenges related to human experiments and fibroblast cultur
Autor:
Erik Kaadt, Lars Aagaard
Publikováno v:
Kaadt, E & Aagaard, L 2016, ' 589. Short Hairpin RNAs Based on miR-451 Show Potent Knockdown without Passenger Strand Activity ' pp. S233-S234 .
Based on the recent findings that RNAi designs with shortened shRNA stems bypass Dicer cleavage and rely on Ago2 for processing of the ‘effector’ guide strand, we have compared designs based on ‘classical’ shRNA structures with shortened stem