Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Erik K. Zhivkoplias"'
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The regulatory relationships between genes and proteins in a cell form a gene regulatory network (GRN) that controls the cellular response to changes in the environment. A number of inference methods to reverse engineer the original GRN from large-sc
Externí odkaz:
https://doaj.org/article/ef0b0eeb4b934e69929c9f00cfac41a3
Publikováno v:
J Virol
Unlike RNA viruses, most DNA viruses replicate their genomes with high-fidelity polymerases that rarely make base substitution errors. Nevertheless, experimental evolution studies have revealed rapid acquisition of adaptive mutations during serial pa
Publikováno v:
Journal of virology. 92(20)
High-throughput DNA sequencing enables the study of experimental evolution in near real time. Until now, mutants with deletions of nonessential host range genes were used in experimental evolution of vaccinia virus (VACV). Here, we guided the selecti