Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Erik Joly"'
Autor:
Pegah Poursharifi, Camille Attané, Yves Mugabo, Anfal Al-Mass, Anindya Ghosh, Clémence Schmitt, Shangang Zhao, Julian Guida, Roxane Lussier, Heidi Erb, Isabelle Chenier, Marie-Line Peyot, Erik Joly, Christophe Noll, André C. Carpentier, S.R. Murthy Madiraju, Marc Prentki
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Enhanced energy expenditure in brown (BAT) and white adipose tissues (WAT) can be therapeutic against metabolic diseases. We examined the thermogenic role of adipose α/β-hydrolase domain 6 (ABHD6), which hydrolyzes monoacylglycerol (MAG), by employ
Externí odkaz:
https://doaj.org/article/e11e5cce8e0b4e328113e9c46cedfd1c
Autor:
Shangang Zhao, Yves Mugabo, Gwynne Ballentine, Camille Attane, Jose Iglesias, Pegah Poursharifi, Dongwei Zhang, Thuy Anne Nguyen, Heidi Erb, Raphael Prentki, Marie-Line Peyot, Erik Joly, Stephanie Tobin, Stephanie Fulton, J. Mark Brown, S.R. Murthy Madiraju, Marc Prentki
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2872-2888 (2016)
Suppression of α/β-domain hydrolase-6 (ABHD6), a monoacylglycerol (MAG) hydrolase, promotes glucose-stimulated insulin secretion by pancreatic β cells. We report here that high-fat-diet-fed ABHD6-KO mice show modestly reduced food intake, decrease
Externí odkaz:
https://doaj.org/article/84a1d24e99c3458a8ee984390c17eca2
Autor:
Jose Iglesias, Julien Lamontagne, Heidi Erb, Sari Gezzar, Shangang Zhao, Erik Joly, Vouy Linh Truong, Kathryn Skorey, Sheldon Crane, S.R.Murthy Madiraju, Marc Prentki
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 1, Pp 131-141 (2016)
Lipids are used as cellular building blocks and condensed energy stores and also act as signaling molecules. The glycerolipid/ fatty acid cycle, encompassing lipolysis and lipogenesis, generates many lipid signals. Reliable procedures are not availab
Externí odkaz:
https://doaj.org/article/aaa0c395233140d88d37074de991673c
Autor:
Shangang Zhao, Pegah Poursharifi, Yves Mugabo, Emily J. Levens, Kevin Vivot, Camille Attane, Jose Iglesias, Marie-line Peyot, Erik Joly, S.R. Murthy Madiraju, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 4, Iss 12, Pp 940-950 (2015)
Objective: α/β-Hydrolase domain-6 (ABHD6) is a newly identified monoacylglycerol (MAG) lipase. We recently reported that it negatively regulates glucose stimulated insulin secretion (GSIS) in the β cells by hydrolyzing lipolysis-derived MAG that a
Externí odkaz:
https://doaj.org/article/e5610cda190f46468b9fa1ed0a75430a
Autor:
Grace Fergusson, Mélanie Éthier, Mélanie Guévremont, Chloé Chrétien, Camille Attané, Erik Joly, Xavier Fioramonti, Marc Prentki, Vincent Poitout, Thierry Alquier
Publikováno v:
Molecular Metabolism, Vol 3, Iss 9, Pp 848-854 (2014)
Objective: The C57Bl/6J (Bl/6J) mouse is the most widely used strain in metabolic research. This strain carries a mutation in nicotinamide nucleotide transhydrogenase (Nnt), a mitochondrial enzyme involved in NADPH production, which has been suggeste
Externí odkaz:
https://doaj.org/article/5c1f011b3d194df790accee2afbb43bb
Autor:
Émilie Pepin, Anfal Al-Mass, Camille Attané, Kezhuo Zhang, Julien Lamontagne, Roxane Lussier, S R Murthy Madiraju, Erik Joly, Neil B Ruderman, Robert Sladek, Marc Prentki, Marie-Line Peyot
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153017 (2016)
Diet induced obese (DIO) mice can be stratified according to their weight gain in response to high fat diet as low responders (LDR) and high responders (HDR). This allows the study of β-cell failure and the transitions to prediabetes (LDR) and early
Externí odkaz:
https://doaj.org/article/a816a82e402c4a1b82063292ec35e8b2
Autor:
Camille Attané, Marie-Line Peyot, Roxane Lussier, Dongwei Zhang, Erik Joly, S R Murthy Madiraju, Marc Prentki
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159165 (2016)
Many metabolic studies employ tissue-specific gene knockout mice, which requires breeding of floxed gene mice, available mostly on C57BL/6N (NN) genetic background, with cre or Flp recombinase-expressing mice, available on C57BL/6J (JJ) background, r
Externí odkaz:
https://doaj.org/article/20f8b6bde0fb4134a26ff3d93c8a4c6e
Autor:
Claudiane Guay, Erik Joly, Emilie Pepin, Annie Barbeau, Lisa Hentsch, Marco Pineda, S R Murthy Madiraju, Henri Brunengraber, Marc Prentki
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77097 (2013)
Cytosolic NADPH may act as one of the signals that couple glucose metabolism to insulin secretion in the pancreatic ß-cell. NADPH levels in the cytoplasm are largely controlled by the cytosolic isoforms of malic enzyme and isocitrate dehydrogenase (
Externí odkaz:
https://doaj.org/article/fc9c21b5e2474577b5507612818a8807
Autor:
Marc Prentki, Roxane Lussier, Anfal Al-Mass, Emily Levens, Marie-Line Peyot, Yves Mugabo, Heidi Erb, S.R. Murthy Madiraju, Pegah Poursharifi, Elite Possik, Julian Guida, Erik Joly, Robert Sladek
Publikováno v:
The FASEB Journal. 35
Autor:
Anfal Al-Mass, Shangang Zhao, Camille Attané, Marie-Line Peyot, Anindya Ghosh, Julian Guida, Pegah Poursharifi, Isabelle Chenier, André C. Carpentier, Marc Prentki, Heidi Erb, S.R. Murthy Madiraju, Clémence Schmitt, Erik Joly, Yves Mugabo, Roxane Lussier, Christophe Noll
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
JCI Insight
JCI Insight
Enhanced energy expenditure in brown (BAT) and white adipose tissues (WAT) can be therapeutic against metabolic diseases. We examined the thermogenic role of adipose α/β-hydrolase domain 6 (ABHD6), which hydrolyzes monoacylglycerol (MAG), by employ