Acute Effects of Insulin Infusion on Kidney Hemodynamic Function in People With Type 2 Diabetes and Normal Kidney Function

Autor: Michaël J.B. van Baar, Erik J.M. van Bommel, Daan J. Touw, Max Nieuwdorp, Jaap A. Joles, Merle M. Krebber, Petter Bjornstad, Daniël H. van Raalte

Publikováno v: van Baar, M J B, van Bommel, E J M, Touw, D J, Nieuwdorp, M, Joles, J A, Krebber, M M, Bjornstad, P & van Raalte, D H 2023, ' Acute Effects of Insulin Infusion on Kidney Hemodynamic Function in People With Type 2 Diabetes and Normal Kidney Function ', Kidney International Reports, vol. 8, no. 4, pp. 916-920 . https://doi.org/10.1016/j.ekir.2023.01.001
Kidney Int Rep
Kidney International Reports, 8(4), 916-920. ELSEVIER SCIENCE INC
Kidney International Reports, 8(4), 916-920. Elsevier Inc.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d2a6c493edcbcdc2567cba340a7c18
https://research.vumc.nl/en/publications/e7bd7a24-40c9-40f4-a5a0-539442f50a78

Kidney hemodynamic profile and systemic vascular function in adults with type 2 diabetes

Autor: Anne C. Hesp, Mark M. Smits, Erik J.M. van Bommel, Marcel H.A. Muskiet, Lennart Tonneijck, Max Nieuwdorp, Mark H.H. Kramer, Jaap A. Joles, Petter Bjornstad, Daniël H. van Raalte

Publikováno v: Journal of Diabetes and its Complications, 36(3):108127. Elsevier Inc.
Hesp, A C, Smits, M M, van Bommel, E J M, Muskiet, M H A, Tonneijck, L, Nieuwdorp, M, Kramer, M H H, Joles, J A, Bjornstad, P & van Raalte, D H 2022, ' Kidney hemodynamic profile and systemic vascular function in adults with type 2 diabetes : Analysis of three clinical trials ', Journal of Diabetes and its Complications, vol. 36, no. 3, 108127 . https://doi.org/10.1016/j.jdiacomp.2022.108127
Journal of diabetes and its complications, 36(3):108127. Elsevier Inc.

Aims: Glomerular hyperfiltration plays a key role in the pathophysiology of diabetic kidney disease (DKD). Mechanisms underlying this adverse hemodynamic profile are incompletely understood. We hypothesized that systemic vascular pathology, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bd6c59ff9f1357538deb8dbd2b67f0
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85123185465&origin=inward

SGLT2 inhibition versus sulfonylurea treatment effects on electrolyte and acid-base balance: secondary analysis of a clinical trial reaching glycemic equipoise: Tubular effects of SGLT2 inhibition in Type 2 diabetes

Autor: Mark H.H. Kramer, Adrian Post, Ele Ferrannini, Marcel H.A. Muskiet, Erik J.M. van Bommel, Daniël H. van Raalte, Daan J Touw, Stephan J. L. Bakker, Max Nieuwdorp, Jaap A. Joles, Frank Geurts, Miranda van Berkel, Ewout J. Hoorn, A.H. Jan Danser

Publikováno v: Clinical science (London, England, 134(23), 3107-3118. Portland Press Ltd.
Clinical Science, 134(23), 3107-3118. Portland Press, Ltd.
Clinical Science, 134, 23, pp. 3107-3118
Clinical science (London, England : 1979), 134(23), 3107-3118
Clinical Science, 134, 3107-3118
van Bommel, E J M, Geurts, F, Muskiet, M H A, Post, A, Bakker, S J L, Danser, A H J, Touw, D J, van Berkel, M, Kramer, M H H, Nieuwdorp, M, Ferrannini, E, Joles, J A, Hoorn, E J & van Raalte, D H 2020, ' SGLT2 inhibition versus sulfonylurea treatment effects on electrolyte and acid-base balance: secondary analysis of a clinical trial reaching glycemic equipoise: Tubular effects of SGLT2 inhibition in Type 2 diabetes ', Clinical science (London, England : 1979), vol. 134, no. 23, pp. 3107-3118 . https://doi.org/10.1042/CS20201274
Clinical Science, 134(23), 3107-3118. PORTLAND PRESS LTD

Sodium–glucose transporter (SGLT)2 inhibitors increase plasma magnesium and plasma phosphate and may cause ketoacidosis, but the contribution of improved glycemic control to these observations as well as effects on other electrolytes and acid–bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e88f7b816c8cec80fdf1b78fab60ac
https://doi.org/10.1042/cs20201274

Whole-body insulin clearance in people with type 2 diabetes and normal kidney function: Relationship with glomerular filtration rate, renal plasma flow, and insulin sensitivity

Autor: Michaël J.B. van Baar, Erik J.M. van Bommel, Mark M. Smits, Daan J. Touw, Max Nieuwdorp, Reinier W. ten Kate, Jaap A. Joles, Daniël H. van Raalte

Publikováno v: Journal of diabetes and its complications, 36(4):108166. Elsevier Inc.
JOURNAL OF DIABETES AND ITS COMPLICATIONS, 36(4):108166. ELSEVIER SCIENCE INC
van Baar, M J B, van Bommel, E J M, Smits, M M, Touw, D J, Nieuwdorp, M, ten Kate, R W, Joles, J A & van Raalte, D H 2022, ' Whole-body insulin clearance in people with type 2 diabetes and normal kidney function : Relationship with glomerular filtration rate, renal plasma flow, and insulin sensitivity ', Journal of Diabetes and its Complications, vol. 36, no. 4, 108166 . https://doi.org/10.1016/j.jdiacomp.2022.108166
Journal of Diabetes and its Complications, 36(4):108166. Elsevier Inc.

OBJECTIVE: Kidney insulin clearance, proposed to be the main route of extra-hepatic insulin clearance, occurs in tubular cells following glomerular filtration and peritubular uptake, a process that may be impaired in people with type 2 diabetes (T2D)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789484750e2e15fc70077d8df0f9922a
https://doi.org/10.1016/j.jdiacomp.2022.108166

The effect of dapagliflozin on apolipoprotein B and glucose fluxes in patients with type 2 diabetes and well-controlled plasma LDL cholesterol

Autor: Kristien E. C. Bouter, Henk Schierbeek, Max Nieuwdorp, Mireille J. Serlie, Mariëtte T. Ackermans, Alinda W. M. Schimmel, Geesje M. Dallinga-Thie, Dewi van Harskamp, Hans Jansen, Daniël H. van Raalte, Erik J.M. van Bommel

Publikováno v: Diabetes, obesity & metabolism, 22(6), 988-996. Wiley-Blackwell
Diabetes, Obesity & Metabolism

Aim To dissect the effects of the sodium-glucose linked transporter 2 inhibitor dapagliflozin on lipid metabolism and assess whether these effects could potentially offset cardiovascular benefit with this drug-class. Materials and methods We assessed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19ba8a7f3f9b51f0595e2a2edafb75e
https://pure.amc.nl/en/publications/the-effect-of-dapagliflozin-on-apolipoprotein-b-and-glucose-fluxes-in-patients-with-type-2-diabetes-and-wellcontrolled-plasma-ldl-cholesterol(86244dc5-b356-4d2e-bd37-19623bdfc690).html