Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Erik Hrabovszky"'
Autor:
Yvette Ruska, Andrea Csibi, Beáta Dorogházi, Anett Szilvásy-Szabó, Petra Mohácsik, Zsuzsanna Környei, Ádám Dénes, Andrea Kádár, Zita Puskár, Erik Hrabovszky, Balázs Gereben, Gábor Wittmann, Csaba Fekete
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Glucagon-like peptide-1 receptor (GLP-1R) agonists are now commonly used to treat type 2 diabetes and obesity. GLP-1R signaling in the spinal cord has been suggested to account for the mild tachycardia caused by GLP-1R agonists, and may also
Externí odkaz:
https://doaj.org/article/d148c75d29844110a7ad30e9a25d1bf6
Autor:
Imre Farkas, Katalin Skrapits, Miklós Sárvári, Balázs Göcz, Szabolcs Takács, Éva Rumpler, Erik Hrabovszky
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Reproduction in mammals is controlled by hypothalamic gonadotropin-releasing hormone (GnRH) neurons. Recent studies from our laboratory established that the basal ganglia of the human brain contain additional large populations of GnRH synthesizing ne
Externí odkaz:
https://doaj.org/article/64ef1f0af29b4a20910d65a6a3aa68fc
Autor:
Florent Sauve, Sreekala Nampoothiri, Sophie A. Clarke, Daniela Fernandois, Caio Fernando Ferreira Coêlho, Julie Dewisme, Edouard G. Mills, Gaetan Ternier, Ludovica Cotellessa, Cristina Iglesias-Garcia, Helge Mueller-Fielitz, Thibaud Lebouvier, Romain Perbet, Vincent Florent, Marc Baroncini, Ariane Sharif, June Ereño-Orbea, Maria Mercado-Gómez, Asis Palazon, Virginie Mattot, Florence Pasquier, Sophie Catteau-Jonard, Maria Martinez-Chantar, Erik Hrabovszky, Mercé Jourdain, Dominique Deplanque, Annamaria Morelli, Giulia Guarnieri, Laurent Storme, Cyril Robil, François Trottein, Ruben Nogueiras, Markus Schwaninger, Pascal Pigny, Julien Poissy, Konstantina Chachlaki, Claude-Alain Maurage, Paolo Giacobini, Waljit Dhillo, S. Rasika, Vincent Prevot
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104784- (2023)
Summary: Background: We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during pathological aging, including Down syndrome and Alzheim
Externí odkaz:
https://doaj.org/article/805ae189cc654b398588ba98e00a06f8
Autor:
Arlene J. George, Bin Dong, Hannah Lail, Morgan Gomez, Yarely C. Hoffiz, Christopher B. Ware, Ning Fang, Anne Z. Murphy, Erik Hrabovszky, Desiree Wanders, Angela M. Mabb
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105108- (2022)
Externí odkaz:
https://doaj.org/article/ca1e57a0e62e4111a9e9a68f461edfb3
Autor:
Balázs Göcz, Szabolcs Takács, Katalin Skrapits, Éva Rumpler, Norbert Solymosi, Szilárd Póliska, William H. Colledge, Erik Hrabovszky, Miklós Sárvári
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Kisspeptin neurons residing in the rostral periventricular area of the third ventricle (KPRP3V) and the arcuate nucleus (KPARC) mediate positive and negative estrogen feedback, respectively. Here, we aim to compare transcriptional responses of KPRP3V
Externí odkaz:
https://doaj.org/article/c5786b8bb3e34753a1ec1478ef4e8dbf
Autor:
Katalin Skrapits, Miklós Sárvári, Imre Farkas, Balázs Göcz, Szabolcs Takács, Éva Rumpler, Viktória Váczi, Csaba Vastagh, Gergely Rácz, András Matolcsy, Norbert Solymosi, Szilárd Póliska, Blanka Tóth, Ferenc Erdélyi, Gábor Szabó, Michael D Culler, Cecile Allet, Ludovica Cotellessa, Vincent Prévot, Paolo Giacobini, Erik Hrabovszky
Publikováno v:
eLife, Vol 10 (2021)
Human reproduction is controlled by ~2000 hypothalamic gonadotropin-releasing hormone (GnRH) neurons. Here, we report the discovery and characterization of additional ~150,000–200,000 GnRH-synthesizing cells in the human basal ganglia and basal for
Externí odkaz:
https://doaj.org/article/a6f90203e0064aa79d6e78b486c43b01
Autor:
Éva Rumpler, Szabolcs Takács, Balázs Göcz, Ferenc Baska, Ottó Szenci, András Horváth, Philippe Ciofi, Erik Hrabovszky, Katalin Skrapits
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Neurons co-synthesizing kisspeptin (KP), neurokinin B (NKB), and dynorphin (“KNDy neurons”) in the hypothalamic arcuate/infundibular nucleus (INF) form a crucial component of the gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) “p
Externí odkaz:
https://doaj.org/article/d17a883a7d7a49539a0b942cd2f30420
Autor:
Zsuzsanna Bardóczi, Tamás Wilheim, Katalin Skrapits, Erik Hrabovszky, Gergely Rácz, András Matolcsy, Zsolt Liposits, Joanna H. Sliwowska, Árpád Dobolyi, Imre Kalló
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Gonadotropin releasing hormone (GnRH) neurons provide neuronal input to the preoptic area (POA) and the arcuate nucleus (Arc), two regions involved critically in the regulation of neuroendocrine functions and associated behaviors. These areas contain
Externí odkaz:
https://doaj.org/article/5ff751f48b5842d8af14ddf097bddcf6
Autor:
Imre Farkas, Csaba Vastagh, Erzsébet Farkas, Flóra Bálint, Katalin Skrapits, Erik Hrabovszky, Csaba Fekete, Zsolt Liposits
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Glucagon-like peptide-1 (GLP-1), a metabolic signal molecule, regulates reproduction, although, the involved molecular mechanisms have not been elucidated, yet. Therefore, responsiveness of gonadotropin-releasing hormone (GnRH) neurons to the GLP-1 a
Externí odkaz:
https://doaj.org/article/5276f74744f94e4b9d9ae316d9ea0059
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88540 (2014)
The innate immune system including microglia has a major contribution to maintenance of the physiological functions of the hippocampus by permanent monitoring of the neural milieu and elimination of tissue-damaging threats. The hippocampus is vulnera
Externí odkaz:
https://doaj.org/article/0c75e2ed1e214e0b9d7b8d0219704d6a