Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Erik Hjorth"'
Autor:
Ceren Emre, Luis E. Arroyo-García, Khanh V. Do, Bokkyoo Jun, Makiko Ohshima, Silvia Gómez Alcalde, Megan L. Cothern, Silvia Maioli, Per Nilsson, Erik Hjorth, André Fisahn, Nicolas G. Bazan, Marianne Schultzberg
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Intranasal administration of pro-resolving lipid mediators improves memory deficits and reduce microglial activation in a mouse model for Alzheimer’s disease, suggesting a future therapy.
Externí odkaz:
https://doaj.org/article/19b3984474bb4b898093a4daa1c00e69
Autor:
Ceren Emre, Khanh V. Do, Bokkyoo Jun, Erik Hjorth, Silvia Gómez Alcalde, Marie-Audrey I. Kautzmann, William C. Gordon, Per Nilsson, Nicolas G. Bazan, Marianne Schultzberg
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-26 (2021)
Abstract Sustained brain chronic inflammation in Alzheimer’s disease (AD) includes glial cell activation, an increase in cytokines and chemokines, and lipid mediators (LMs), concomitant with decreased pro-homeostatic mediators. The inflammatory res
Externí odkaz:
https://doaj.org/article/ac96393851724d43b1cdd2767bc6342b
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 11 (2018)
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive memory loss and dementia. Accumulating evidence suggests that inflammation is involved in the pathogenesis of AD. Epidemiological studies suggest that use of anti-
Externí odkaz:
https://doaj.org/article/4be1a35b1fdd49bdb4ec4511401d3726
Autor:
Xiuzhe Wang, Erik Hjorth, Inger Vedin, Maria Eriksdotter, Yvonne Freund-Levi, Lars-Olof Wahlund, Tommy Cederholm, Jan Palmblad, Marianne Schultzberg
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 3, Pp 674-681 (2015)
Specialized proresolving mediators (SPMs) induce resolution of inflammation. SPMs are derivatives of n-3 and n-6 PUFAs and may mediate their beneficial effects. It is unknown whether supplementation with PUFAs influences the production of SPMs. Alzhe
Externí odkaz:
https://doaj.org/article/85d04510a8f441548ff1400100c09aa1
Autor:
Inger Vedin, Tommy Cederholm, Yvonne Freund-Levi, Hans Basun, Erik Hjorth, Gerd Faxén Irving, Maria Eriksdotter-Jönhagen, Marianne Schultzberg, Lars-Olof Wahlund, Jan Palmblad
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 5, Pp 1179-1185 (2010)
Omega-3 fatty acids, e.g., dokosahexaenoic acid (DHA) and eikosapentaenoic acid (EPA), ameliorate inflammatory reactions by various mechanisms, but the role of prostaglandins remains unclear. Our aim was to determine if dietary supplementation with a
Externí odkaz:
https://doaj.org/article/e473dab620f946ad89e24671c779fe2e
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2010 (2010)
Glial activation and increased inflammation characterize neuropathology in Alzheimer's disease (AD). The aim was to develop a model for studying phagocytosis of 𝛽-amyloid (A𝛽) peptide by human microglia and to test effects thereupon by immunomo
Externí odkaz:
https://doaj.org/article/adc5858f0fda4cb88f57483770ea28bf
Autor:
Khanh V. Do, Erik Hjorth, Ying Wang, Bokkyoo Jun, Marie-Audrey I. Kautzmann, Makiko Ohshima, Maria Eriksdotter, Marianne Schultzberg, Nicolas G. Bazan
Publikováno v:
Cellular and Molecular Neurobiology. 43:797-811
Alzheimer’s disease (AD) develops into dementia over a period of several years, during which subjective cognitive impairment (SCI) and mild cognitive impairment (MCI) can be used as intermediary diagnoses of increasing severity. Chronic neuroinflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10806f575868ceeb8f2c31d93276f057
https://doi.org/10.1007/s10571-022-01216-5
https://doi.org/10.1007/s10571-022-01216-5
Autor:
Maria Eriksdotter, Avin Tofiq, Tommy Cederholm, Henrik Zetterberg, Marianne Schultzberg, Hans Basun, Gerd Faxén-Irving, Yvonne Freund-Levi, Erik Hjorth, Fredrik Jernerén, Lars-Olof Wahlund, Jan Palmblad, Kaj Blennow
Publikováno v:
Journal of Alzheimer's Disease. 83:1291-1301
Background: Studies have suggested a connection between a decrease in the levels of polyunsaturated fatty acids (PUFAs) and Alzheimer’s disease (AD). We aimed to assess the effect of supplementation with omega-3 fatty acids (n-3 FAs) on biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73db003987fe4e5fec6270c120bd0108
https://doi.org/10.3233/jad-210007
https://doi.org/10.3233/jad-210007