Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Erik Hermansson"'
Autor:
Erik Hermansson, Sebastian Schultz, Damian Crowther, Sara Linse, Bengt Winblad, Gunilla Westermark, Jan Johansson, Jenny Presto
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 6, Pp 659-665 (2014)
Aggregation of the amyloid-β peptide (Aβ) into toxic oligomers and amyloid fibrils is linked to the development of Alzheimer’s disease (AD). Mutations of the BRICHOS chaperone domain are associated with amyloid disease and recent in vitro data sh
Externí odkaz:
https://doaj.org/article/c23db1b019664379a3ffdb2d957ae5c3
Autor:
Erik Hermansson, David Svensson
Publikováno v:
Computational Science and Its Applications – ICCSA 2021 ISBN: 9783030869724
ICCSA (4)
ICCSA (4)
The recent years have seen a rapid development in the general Machine Learning area and a similar strong trend has taken place within the drug development domain, known as Precision Medicine. Traditionally, the main focus in clinical trials has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61364b5c999e668f6c5c1a930937892d
https://doi.org/10.1007/978-3-030-86973-1_44
https://doi.org/10.1007/978-3-030-86973-1_44
Autor:
Firoz Roshan Kurudenkandy, Helen Poska, Jenny Presto, Sophie Crux, Martin Haslbeck, Henrik Biverstål, Erik Hermansson, Jan Johansson, Gefei Chen, André Fisahn, George Kostallas, Axel Abelein
Publikováno v:
Biochemical journal 473(20), 3683-3704 (2016). doi:10.1042/BCJ20160277
Formation of fibrils of the amyloid-β peptide (Aβ) is suggested to play a central role in neurodegeneration in Alzheimer's disease (AD), for which no effective treatment exists. The BRICHOS domain is a part of several disease-related proproteins, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15506920f3caad5dc42e7781da33734
https://pub.dzne.de/record/139035
https://pub.dzne.de/record/139035
Publikováno v:
FEBS Journal. 278:3893-3904
The BRICHOS domain was initially defined from sequence alignments of the Bri protein associated with familial dementia, chondromodulin associated with chondrosarcoma and surfactant protein C precursor (proSP-C) associated with respiratory distress sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d00c108b565e9f41e1e36087e9572184
https://doi.org/10.1111/j.1742-4658.2011.08209.x
https://doi.org/10.1111/j.1742-4658.2011.08209.x
Autor:
Erik Lundgren, Per Westermark, Robert Kisilevsky, Ana M. Damas, John B. Ancsin, Erik Hermansson, Fredrik Noborn, Jan Johansson, Jin-Ping Li, Ingrid Dacklin, Xiao Zhang, Paul O'Callaghan, Jenny Presto, Maria João Saraiva
Publikováno v:
Proceedings of the National Academy of Sciences. 108:5584-5589
Transthyretin (TTR) is a homotetrameric protein that transports thyroxine and retinol. Tetramer destabilization and misfolding of the released monomers result in TTR aggregation, leading to its deposition as amyloid primarily in the heart and periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75afea667991d7acdd17bc6943605ed2
https://doi.org/10.1073/pnas.1101194108
https://doi.org/10.1073/pnas.1101194108
Autor:
Henrik Biverstål, Axel Leppert, Jan Johansson, Mara Reifenrath, Jenny Presto, Erik Hermansson, Bengt Winblad, Lisa Dolfe
Publikováno v:
Biochimica et biophysica acta. 1854(8)
The BRICHOS domain is associated with human amyloid disease, and it efficiently prevents amyloid fibril formation of the amyloid β-peptide (Aβ) in vitro and in vivo. Recombinant human prosurfactant protein C (proSP-C) BRICHOS domain forms a homotri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495518c642fbb5990e9f5a1cc17bf4fa
https://pubmed.ncbi.nlm.nih.gov/25891900
https://pubmed.ncbi.nlm.nih.gov/25891900
Autor:
Sara Linse, Gunilla T. Westermark, Jenny Presto, Damian C. Crowther, Bengt Winblad, Sebastian W. Schultz, Jan Johansson, Erik Hermansson
Publikováno v:
Disease Models & Mechanisms.
Aggregation of the amyloid β-peptide (Aβ) into toxic oligomers and amyloid fibrils is linked to the development of Alzheimer's disease (AD). Mutations of the BRICHOS domain are associated with amyloid disease and recent in vitro data show that BRIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::352b0012d44da0e7ad397ce1e4f1e7db
https://doi.org/10.1242/dmm.014787
https://doi.org/10.1242/dmm.014787
Autor:
Erik Hermansson, Gunilla T. Westermark, Jan Johansson, Jenny Presto, Bengt Winblad, Krishnapriya Loganathan, Damian C. Crowther
Publikováno v:
Alzheimer's & Dementia. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aabbe5e37368d08815d1400d4378432
https://doi.org/10.1016/j.jalz.2013.04.049
https://doi.org/10.1016/j.jalz.2013.04.049
Autor:
Hanna Willander, Per Westermark, Michael Landreh, Aaron Hamvas, Jenny Presto, Johan Åqvist, Hans Jörnvall, Henrik Keränen, Glareh Askarieh, Tomas Bergman, Helena Berglund, Lawrence M. Nogee, Stefan D. Knight, Jan Johansson, Cristina Casals, Alejandra Sáenz, Erik Hermansson, Kerstin Nordling
BRICHOS domains are encoded in > 30 human genes, which are associated with cancer, neurodegeneration, and interstitial lung disease (ILD). The BRICHOS domain from lung surfactant protein C proprotein (proSP-C) is required for membrane insertion of SP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9bea3053a271a05660e6acf4869cef
https://europepmc.org/articles/PMC3289314/
https://europepmc.org/articles/PMC3289314/
Autor:
Jenny Presto, Erik Hermansson, Sara Linse, Stefan D. Knight, G. Askarieh, Hanna Willander, Jan Johansson
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::247852ff922b9f569b53a807b4e129d0
https://doi.org/10.1016/j.jalz.2011.05.1756
https://doi.org/10.1016/j.jalz.2011.05.1756