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pro vyhledávání: '"Erik Gjerstadt"'
Autor:
Erik Gjerstadt, Ellen Sanford, William D. Shrader, Ellen M. Leahy, Paul A. Sprengeler, Steve Torkelson, Roopa Rai, Juthamas Sukbuntherng, Huiyong Hu, Dange Vijaykumar, Ronnell Cabuslay, Colin O’Bryan, Jennifer R. Riggs, Liang Liu, Wendy B. Young, Tony Ton, Michael B. Shaghafi
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(14)
Efforts toward developing orally bioavailable factor VIIa inhibitors starting from parenteral lead compound 1 are described. SAR resulted in improved physicochemical properties, leading to enhanced oral absorption in rat.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0763c6af115b95efd98bed0abab2d60
https://pubmed.ncbi.nlm.nih.gov/16650987
https://pubmed.ncbi.nlm.nih.gov/16650987
