Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Erik Gaitzsch"'
Autor:
Elham Khatamzas, Markus H. Antwerpen, Alexandra Rehn, Alexander Graf, Johannes Christian Hellmuth, Alexandra Hollaus, Anne-Wiebe Mohr, Erik Gaitzsch, Tobias Weiglein, Enrico Georgi, Clemens Scherer, Stephanie-Susanne Stecher, Stefanie Gruetzner, Helmut Blum, Stefan Krebs, Anna Reischer, Alexandra Leutbecher, Marion Subklewe, Andrea Dick, Sabine Zange, Philipp Girl, Katharina Müller, Oliver Weigert, Karl-Peter Hopfner, Hans-Joachim Stemmler, Michael von Bergwelt-Baildon, Oliver T. Keppler, Roman Wölfel, Maximilian Muenchhoff, Andreas Moosmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
SARS-CoV-2 mutations associated with the escape from antibody-mediated neutralization have been widely reported. Here, in a patient with defective antibody responses, the authors find a potential association between SARS-CoV-2 mutations and CD8 T alt
Externí odkaz:
https://doaj.org/article/938422b96025423598b966f651261064
Autor:
Erik Gaitzsch, Verena Passerini, Elham Khatamzas, Carolin D. Strobl, Maximilian Muenchhoff, Clemens Scherer, Andreas Osterman, Michael Heide, Anna Reischer, Marion Subklewe, Alexandra Leutbecher, Benjamin Tast, Adrian Ruhle, Tobias Weiglein, Stephanie-Susanne Stecher, Hans J. Stemmler, Martin Dreyling, Philipp Girl, Enrico Georgi, Roman Wölfel, Laura Mateyka, Elvira D’Ippolito, Kilian Schober, Dirk H. Busch, Juliane Kager, Christoph D. Spinner, Matthias Treiber, Sebastian Rasch, Tobias Lahmer, Roman Iakoubov, Jochen Schneider, Ulrike Protzer, Christof Winter, Jürgen Ruland, Michael Quante, Oliver T. Keppler, Michael von Bergwelt-Baildon, Johannes Hellmuth, Oliver Weigert
Publikováno v:
HemaSphere, Vol 5, Iss 7, p e603 (2021)
The clinical and immunological impact of B-cell depletion in the context of coronavirus disease 2019 (COVID-19) is unclear. We conducted a prospectively planned analysis of COVID-19 in patients who received B-cell depleting anti-CD20 antibodies and c
Externí odkaz:
https://doaj.org/article/094ad305bd0d4e23983309dd91f61e83
Autor:
Deepak Bararia, Johannes A. Hildebrand, Sebastian Stolz, Sarah Haebe, Stefan Alig, Christopher P. Trevisani, Francisco Osorio-Barrios, Michael D. Bartoschek, Michael Mentz, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, Katharina Rautter, Jay Gunawardana, Muhammed B. Sabdia, Monika Szczepanowski, Julia Richter, Wolfram Klapper, Abner Louissaint, Jr., Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, Michael von Bergwelt-Baildon, Christian Steidl, Robert Kridel, Joshua W.D. Tobin, Maher K. Gandhi, David M. Weinstock, Marc Schmidt-Supprian, Menyhárt B. Sárosi, Martina Rudelius, Verena Passerini, Josef Mautner, Oliver Weigert
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: Tumor cells orchestrate their microenvironment. Here, we provide biochemical, structural, functional, and clinical evidence that Cathepsin S (CTSS) alterations induce a tumor-promoting immune microenvironment in follicular lymphoma (FL). We
Externí odkaz:
https://doaj.org/article/0a5e722ca6e94029b574353537c7475f
Autor:
Joachim Pircher, Thomas Czermak, Andreas Ehrlich, Clemens Eberle, Erik Gaitzsch, Andreas Margraf, Jochen Grommes, Prakash Saha, Anna Titova, Hellen Ishikawa-Ankerhold, Konstantin Stark, Tobias Petzold, Thomas Stocker, Ludwig T Weckbach, Julia Novotny, Markus Sperandio, Bernhard Nieswandt, Alberto Smith, Hanna Mannell, Barbara Walzog, David Horst, Oliver Soehnlein, Steffen Massberg, Christian Schulz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Cathelicidins are antimicrobial peptides that eliminate pathogens and contribute to the innate immune response. Here the authors show that neutrophil-derived LL-37/CRAMP induces platelet activation and promotes arterial thrombosis and thrombo-inflamm
Externí odkaz:
https://doaj.org/article/8a00ffc239a5482690c1439aabca24d4
Autor:
Erik Gaitzsch, Thomas Czermak, Andrea Ribeiro, Yvonn Heun, Monica Bohmer, Monika Merkle, Hanna Mannell, Christian Schulz, Markus Wörnle, Joachim Pircher
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Double-stranded DNA (dsDNA) constitutes a potent activator of innate immunity, given its ability to bind intracellular pattern recognition receptors during viral infections or sterile tissue damage. While effects of dsDNA in immune cells hav
Externí odkaz:
https://doaj.org/article/3223fb986f184a3bb004e31aaba168a0
Autor:
Stefan K Alig, Yvonn Stampnik, Joachim Pircher, Raffaela Rotter, Erik Gaitzsch, Andrea Ribeiro, Markus Wörnle, Florian Krötz, Hanna Mannell
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121113 (2015)
The tyrosine phosphatase SHP-1 negatively influences endothelial function, such as VEGF signaling and reactive oxygen species (ROS) formation, and has been shown to influence angiogenesis during tissue ischemia. In ischemic tissues, hypoxia induced a
Externí odkaz:
https://doaj.org/article/138d34506a2247ae85c7289ed46f399b
Autor:
Joachim Pircher, Thomas Czermak, Monika Merkle, Hanna Mannell, Florian Krötz, Andrea Ribeiro, Volker Vielhauer, Jonathan Nadjiri, Erik Gaitzsch, Markus Niemeyer, Stefan Porubsky, Hermann-Josef Gröne, Markus Wörnle
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113351 (2014)
In hepatitis C virus (HCV) infection, morbidity and mortality often result from extrahepatic disease manifestations. We provide evidence for a role of receptors of the innate immune system in virally induced inflammation of the endothelium in vitro a
Externí odkaz:
https://doaj.org/article/9fc5981b58094016bc8b7cbdc7b52261
Autor:
Elisabeth Koch, Joachim Pircher, Thomas Czermak, Erik Gaitzsch, Stefan Alig, Hanna Mannell, Markus Niemeyer, Florian Krötz, Markus Wörnle
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Introduction. Inflammation and endothelium-derived superoxides are important pathomechanisms in atherothrombotic diseases. We could previously show that the tyrosine phosphatase SHP-1 acts as a negative regulator in endothelial superoxide production.
Externí odkaz:
https://doaj.org/article/b34079ea41cd48baab01b33ff6091694
Autor:
Alfred C. Feller, Harald Stein, Wolfram Klapper, Andreas Rosenwald, Vindi Jurinovic, Michael Unterhalt, Verena Passerini, William David Keay, Christiane Pott, Annette M. Staiger, Stefan Alig, German Ott, Heike Horn, Sarah Haebe, Erik Gaitzsch, Mohammad Shahrokh Esfahani, Ash A. Alizadeh, Natyra Tahiri, Martin Dreyling, Johannes C. Hellmuth, Christian Schmidt, Eva Hoster, Martin-Leo Hansmann, Oliver Weigert, Wolfgang Hiddemann, Anna-Katharina Zoellner
Publikováno v:
Blood Adv
High-dose therapy and autologous stem cell transplantation (HDT/ASCT) is an effective salvage treatment for eligible patients with follicular lymphoma (FL) and early progression of disease (POD). Since the introduction of rituximab, HDT/ASCT is no lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3143b3993776c71324f3558a99a9033c
https://doi.org/10.1182/bloodadvances.2020002546
https://doi.org/10.1182/bloodadvances.2020002546
Autor:
Oliver Weigert, Erik Gaitzsch
Publikováno v:
TumorDiagnostik & Therapie. 41:240-245
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b2969464e6796a0a93ffe1c1a86e36a
https://doi.org/10.1055/a-1103-8770
https://doi.org/10.1055/a-1103-8770