Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Erik Freier"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Bioproduction of plant-derived triterpenoids in recombinant microbes is receiving great attention to make these biologically active compounds industrially accessible as nutraceuticals, pharmaceutics, and cosmetic ingredients. So far, th
Externí odkaz:
https://doaj.org/article/2a45d7e760734952910177e95d7f8ce2
Autor:
Andreas Hentschel, Artur Czech, Ute Münchberg, Erik Freier, Ulrike Schara-Schmidt, Albert Sickmann, Jens Reimann, Andreas Roos
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background The elucidation of pathomechanisms leading to the manifestation of rare (genetically caused) neurological diseases including neuromuscular diseases (NMD) represents an important step toward the understanding of the genesis of the
Externí odkaz:
https://doaj.org/article/c0bba7d671bf421f922be0080e320a0a
Autor:
Huaiguang Li, Ute Münchberg, Alaa A. Oughli, Darren Buesen, Wolfgang Lubitz, Erik Freier, Nicolas Plumeré
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Oxidative degradation impedes practical applications of highly active but fragile catalysts. Here the authors show that combining a protection matrix for O2 reduction and hydrogen peroxide decomposition stabilizes highly O2-sensitive hydrogenase in t
Externí odkaz:
https://doaj.org/article/c8dfcdbecf404d3ca4aae12c40bcbe41
Autor:
Matthew J. Jennings, Denisa Hathazi, Chi D. L. Nguyen, Benjamin Munro, Ute Münchberg, Robert Ahrends, Annette Schenck, Ilse Eidhof, Erik Freier, Matthis Synofzik, Rita Horvath, Andreas Roos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Recessive mutations in DNAJC3, an endoplasmic reticulum (ER)-resident BiP co-chaperone, have been identified in patients with multisystemic neurodegeneration and diabetes mellitus. To further unravel these pathomechanisms, we employed a non-biased pr
Externí odkaz:
https://doaj.org/article/d37f7a362bf742d5823db37a44e3b415
Autor:
Elen Tolstik, Nairveen Ali, Shuxia Guo, Paul Ebersbach, Dorothe Möllmann, Paula Arias-Loza, Johann Dierks, Irina Schuler, Erik Freier, Jörg Debus, Hideo A. Baba, Peter Nordbeck, Thomas Bocklitz, Kristina Lorenz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5345 (2022)
Vibrational spectroscopy can detect characteristic biomolecular signatures and thus has the potential to support diagnostics. Fabry disease (FD) is a lipid disorder disease that leads to accumulations of globotriaosylceramide in different organs, inc
Externí odkaz:
https://doaj.org/article/3de0c58c4b754d128301622d32a412b4
Publikováno v:
BMC Plant Biology, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Cannabis possesses a rich spectrum of phytochemicals i.e. cannabinoids, terpenes and phenolic compounds of industrial and medicinal interests. Most of these high-value plant products are synthesised in the disk cells and stored in
Externí odkaz:
https://doaj.org/article/dd66991337ca4ea4a13833c68b9237cd
Autor:
José Andrés González Coraspe, Joachim Weis, Mary E. Anderson, Ute Münchberg, Kristina Lorenz, Stephan Buchkremer, Stephanie Carr, René Peiman Zahedi, Eva Brauers, Hannah Michels, Yoshihide Sunada, Hanns Lochmüller, Kevin P. Campbell, Erik Freier, Denisa Hathazi, Andreas Roos
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-19 (2018)
Abstract Background Caveolin-3 (CAV3) is a muscle-specific protein localized to the sarcolemma. It was suggested that CAV3 is involved in the connection between the extracellular matrix (ECM) and the cytoskeleton. Caveolinopathies often go along with
Externí odkaz:
https://doaj.org/article/6d998471d66f4de781e502ffc59dcddf
Autor:
Adela Della Marina, Annabelle Arlt, Ulrike Schara-Schmidt, Christel Depienne, Andrea Gangfuß, Heike Kölbel, Albert Sickmann, Erik Freier, Nicolai Kohlschmidt, Andreas Hentschel, Joachim Weis, Artur Czech, Anika Grüneboom, Andreas Roos
Publikováno v:
Cells, Vol 10, Iss 12, p 3481 (2021)
Background: Presynaptic forms of congenital myasthenic syndromes (CMS) due to pathogenic variants in SLC18A3 impairing the synthesis and recycling of acetylcholine (ACh) have recently been described. SLC18A3 encodes the vesicular ACh transporter (VAC
Externí odkaz:
https://doaj.org/article/0252c72e66eb47dbb39bde7dfaa99d67
Publikováno v:
Analytical Chemistry. 93:7204-7209
We present a novel multi-emitter electrospray ionization (ESI) interface for the coupling of microfluidic free-flow electrophoresis (μFFE) with mass spectrometry (MS). The effluents of the μFFE outlets are analyzed in near real-time, allowing a dir