Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Erik Faessler"'
Autor:
Anna L. Fricke, Wignand W. D. Mühlhäuser, Lena Reimann, Johannes P. Zimmermann, Christa Reichenbach, Bettina Knapp, Christian D. Peikert, Alexander M. Heberle, Erik Faessler, Sascha Schäuble, Udo Hahn, Kathrin Thedieck, Gerald Radziwill, Bettina Warscheid
Publikováno v:
Journal of Proteome Research, 22(3), 768-789. NLM (Medline)
Phosphorylation-dependent signal transduction plays an important role in regulating the functions and fate of skeletal muscle cells. Central players in the phospho-signaling network are the protein kinases AKT, S6K, and RSK as part of the PI3K-AKT-mT
Publikováno v:
Nucleic Acids Research.
We present GePI, a novel Web server for large-scale text mining of molecular interactions from the scientific biomedical literature. GePI leverages natural language processing techniques to identify genes and related entities, interactions between th
Autor:
Loreen Thürmann, Matthias Klös, Sebastian D. Mackowiak, Matthias Bieg, Tobias Bauer, Naveed Ishaque, Marey Messingschlager, Carl Herrmann, Stefan Röder, Mario Bauer, Sascha Schäuble, Erik Faessler, Udo Hahn, Dieter Weichenhan, Oliver Mücke, Christoph Plass, Michael Borte, Erika von Mutius, Gabriele I. Stangl, Roger Lauener, Anne M. Karvonen, Amandine Divaret‐Chauveau, Josef Riedler, Joachim Heinrich, Marie Standl, Andrea von Berg, Beate Schaaf, Gunda Herberth, Michael Kabesch, Roland Eils, Saskia Trump, Irina Lehmann
Publikováno v:
Allergy.
MotivationKnowledge about interactions between genes and proteins is vital for bio-molecular research. A large part of this knowledge is published in written text and not accessible in a structured way. To remedy this situation, several repositories
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3bd448878ca3b796bc9ac5c40cb8cb4
https://doi.org/10.1101/2022.07.08.499305
https://doi.org/10.1101/2022.07.08.499305
Publikováno v:
SIGIR
From 2017 to 2019 the Text REtrieval Conference (TREC) held a challenge task on precision medicine using documents from medical publications (PubMed) and clinical trials. Despite lots of performance measurements carried out in these evaluation campai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfe998aabd85a0c245909101fc822fe
Autor:
Lena Reimann, Friedel Drepper, Sascha Schäuble, Christian D. Peikert, Wignand W. D. Mühlhäuser, Dieter O. Fürst, Yvonne Leber, Peter F.M. van der Ven, Clemens Kreutz, Heike Wiese, Keerthika Lohanadan, Anja N. Schwäble, Christa Reichenbach, Erik Faessler, Bettina Knapp, Kristina Djinović-Carugo, Bettina Warscheid, Gerald Radziwill, Anna L. Fricke, Udo Hahn, Martin Puchinger
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-19 (2020)
Communications Biology
Communications Biology
The PI3K/Akt pathway promotes skeletal muscle growth and myogenic differentiation. Although its importance in skeletal muscle biology is well documented, many of its substrates remain to be identified. We here studied PI3K/Akt signaling in contractin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251bee94ac9e94781665506b4a5825b5
https://doi.org/10.1038/s42003-020-0982-5
https://doi.org/10.1038/s42003-020-0982-5
Autor:
Patricia Razquin Navas, Udo Hahn, Kathrin Thedieck, Erik Faessler, Christine Sers, Katharina Kasack, Ahmed Sadik, Christiane A. Opitz, Miriam Langelaar-Makkinje, Philip Marx-Stoelting, Sascha Schäuble, Ines Heiland, Alexander Martin Heberle
Publikováno v:
Life Science Alliance
Life science alliance, 2(2):201800257. Life Science Alliance LLC
Life science alliance, 2(2):201800257. Life Science Alliance LLC
PI3K and p38 act in a hierarchical manner to enhance mTORC1 activity and stress granule formation; although PI3K is the main driver, the impact of p38 gets apparent as PI3K activity declines.
All cells and organisms exhibit stress-coping mechani
All cells and organisms exhibit stress-coping mechani
Autor:
Christiane A. Opitz, Alexander Böhme, Saskia Trump, Erik Faessler, Mirja Tamara Prentzell, Friederike Reuter, Andreas von Deimling, Walter E. Haefeli, Bianca Berdel, Evelyn Jäger, Carina Ramallo Guevara, Verena Kalter, Marc Zapatka, Jessica C. Hassel, Sascha Schäuble, Gernot Poschet, Annekathrin Reinhardt, Jürgen Burhenne, Mansour Sobeh, Naveed Ishaque, Carsten Hopf, Martina Seiffert, Philipp F Secker, Rita Schlichting, Stefanie Loth, Beate I. Escher, Luis F. Somarribas Patterson, Selcen Öztürk, Udo Hahn, Soumya R. Mohapatra, Kathrin Thedieck, Pauline Pfänder, Isabelle Kirst, Ahmed Sadik, Murat Iskar, Thomas Hielscher, Verena Panitz, Kathrin I. Foerster, Heba Salem
Publikováno v:
Cell
Cell, 182(5), 1252-1270.e34. CELL PRESS
Cell, 182(5), 1252-1270.e34. CELL PRESS
Aryl hydrocarbon receptor (AHR) activation by tryptophan (Trp) catabolites enhances tumor malignancy and suppresses anti-tumor immunity. The context specificity of AHR target genes has so far impeded systematic investigation of AHR activity and its u
Autor:
Erik Faessler, Udo Hahn
Publikováno v:
DocEng
This paper introduces the Jena Document Information System (JeDIS). The focus lies on its capability to partition annotation graphs into modules. Annotation modules are defined in terms of types from the annotation schema. Modules allow easy manipula
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783319586939
EKAW (Satellite Events)
EKAW (Satellite Events)
We present Joyce, a scalable tool for identifying and assembling relevant (pieces of) ontologies from a repository of source ontologies, thus enabling the effective and efficient reuse of formalized domain knowledge. Joyce includes a conceptual filte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3f4a8fc12ca46f7a1aaa98b06283ef6
https://doi.org/10.1007/978-3-319-58694-6_12
https://doi.org/10.1007/978-3-319-58694-6_12