Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Erik F. Flemington"'
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Abstract Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obes
Externí odkaz:
https://doaj.org/article/dad0fa3c4c914a0ebba7e45d5f2c7f93
Autor:
Harrison M. Penrose, Rida Iftikhar, Morgan E. Collins, Eman Toraih, Emmanuelle Ruiz, Nathan Ungerleider, Hani Nakhoul, Erik F. Flemington, Emad Kandil, Shamita B. Shah, Suzana D. Savkovic
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expres
Externí odkaz:
https://doaj.org/article/e760a94f0fe148a6a82d2a1f02490469
Autor:
Emmanuelle Ruiz, Harrison M. Penrose, Sandra Heller, Hani Nakhoul, Melody Baddoo, Erik F. Flemington, Emad Kandil, Suzana D. Savkovic
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 350-363 (2020)
Inflammatory bowel disease (IBD) has been linked to active signaling with bacterial components and reduced mitochondrial ATP production; however, synergism between both of these disease characteristics remains unclear. We aimed to determine in human
Externí odkaz:
https://doaj.org/article/15355e26874241f1bf6b0de62ccbd1f3
Autor:
Harrison M. Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Melody Baddoo, Alifiani B. Hartono, Sean B. Lee, Matthew E. Burow, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 391-408 (2019)
Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular c
Externí odkaz:
https://doaj.org/article/7337e8aa807f4d11a94daa9ce23793f7
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/df3e440f84514614aa5dd372b8cc26ab
Autor:
Augusto C. Ochoa, E F Cromwell, H Brown, Elizabeth C. Martin, O Sirenko, Krzysztof Moroz, Matthew E. Burow, A M Ham, Katherine Hebert, S Sinha, Erik F. Flemington, Jovanny Zabaleta, Hope E. Burks, Jacob Bursavich, Margarite D. Matossian, A I Riker, Steven Elliott, Bridgette M. Collins-Burow, Khoa Nguyen, Maryl K. Wright, Gabrielle O. Windsor, Frank H. Lau, Connor T. King, Henri Wathieu, Reza Izadpanah, Melody Baddoo, Madlin Alzoubi, Arnold H. Zea, Tiffany R. Chang, Lucio Miele, Rachel A. Sabol, Bruce A. Bunnell, J J Savoie
Publikováno v:
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse molecular and histological heterogeneity. Patient-derived xenografts (PDXs) provide a translat
Autor:
Morgan E. Collins, Frank H. Lau, Erik F. Flemington, Suzana D. Savkovic, Harrison M. Penrose, Rida Iftikhar, Alifiani B. Hartono, Sean Bong Lee, Angelle N. King, Susan E. Crawford, Melody Baddoo, Joshua S. Samudre
Publikováno v:
Oncogenesis
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obesity-drive
Autor:
Emmanuelle Ruiz, Harrison M. Penrose, Emad Kandil, Erik F. Flemington, Suzana D. Savkovic, Hani Nakhoul, Sandra Heller, Melody Baddoo
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 350-363 (2020)
Gut Microbes
Gut Microbes
Inflammatory bowel disease (IBD) has been linked to active signaling with bacterial components and reduced mitochondrial ATP production; however, synergism between both of these disease characteristics remains unclear. We aimed to determine in human
Autor:
Erik F. Flemington, Sean B. Lee, Sandra Heller, Chloe Cable, Matthew E. Burow, Melody Baddoo, Nathan Ungerleider, Suzana D. Savkovic, Harrison M. Penrose, Susan E. Crawford, Alifiani B. Hartono, Hani Nakhoul
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 391-408 (2019)
Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular c
Autor:
Emmanuelle Ruiz, Hani Nakhoul, Morgan E. Collins, Shamita B. Shah, Harrison M. Penrose, Eman A. Toraih, Emad Kandil, Erik F. Flemington, Rida Iftikhar, Nathan Ungerleider, Suzana D. Savkovic
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expressed genes