Abstract 442: Developing a lipogenesis inhibitor for prostate cancer

Autor: Dallin Lowder, Jin Na Shin, Maria E. Ruiz-Echartea, Darlene Skapura, Jenny Deng, Aleksandra Rusin, Christel Davis, Erik Ehli, Cristian Coarfa, Michael Ittmann, Salma Kaochar

Publikováno v: Cancer Research. 83:442-442

Background: Prostate cancer (PC) is the single most common and second most lethal cancer in men. Despite therapeutic advances in androgen receptor (AR)-targeting agents, progression to lethal, drug-resistant, castration-resistant prostate cancer (CRP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85491109ec292e4e27717cfc310b10d8
https://doi.org/10.1158/1538-7445.am2023-442

DNA methylation in peripheral tissues and Left-handedness

Autor: Veronika Odintsova, Matthew Sudermann, Fiona Hagenbeek, Doretta Caramaschi, Jouke-Jan Hottenga, Rene Pool, Biobank-based Integrative Omics Study Consortium BIOS, Conor Dolan, Lannie Ligthart, Catharina van Beijsterveldt, Gonneke Willemsen, Eco de Geus, Jeffrey Beck, Erik Ehli, Gabriel Cuellar-Partida, David Evans, Sarah Medland, Caroline Relton, Dorret Boomsma, Jenny van Dongen

Handedness has low heritability and epigenetic mechanisms have been proposed as an etiological mechanism. To examine this hypothesis, we performed an epigenome-wide association study (EWAS) of left-handedness. In a meta-analysis of 3,914 adults of wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb0275adbeff7d206b33fa2d9aeff814
https://doi.org/10.21203/rs.3.rs-375556/v2

Effect of Genome and Environment on Metabolic and Inflammatory Profiles

Autor: Marina Sirota, Eco J. C. de Geus, David R. Cox, Dorret I. Boomsma, Sean Kennedy, Purnima Sundar, Steven J. Pitts, Karen E. Malone, Cornelis Kluft, S. Dusko Ehrlich, Edi Prifti, Shobha Potluri, Gonneke Willemsen, Jacoline Neuteboom

Publikováno v: Sirota, M, Willemsen, G, Sundar, P, Pitts, S J, Potluri, S, Prifti, E, Kennedy, S H, Ehrlich, S D, Neuteboom, J, Kluft, C, Malone, K E, Cox, D R, de Geus, E J C & Boomsma, D I 2015, ' Effect of Genome and Environment on Metabolic and Inflammatory Profiles ', PLoS ONE, vol. 10, no. 4, e0120898, pp. e0120898 . https://doi.org/10.1371/journal.pone.0120898
PLoS ONE, Vol 10, Iss 4, p e0120898 (2015)
PLoS ONE
PLoS ONE, Public Library of Science, 2015, 10 (4), pp.e0120898. ⟨10.1371/journal.pone.0120898⟩
Plos One 4 (10), . (2015)
PloS one, vol 10, iss 4
PLoS ONE, 10(4):e0120898. Public Library of Science

Twin and family studies have established the contribution of genetic factors to variation in metabolic, hematologic and immunological parameters. The majority of these studies analyzed single or combined traits into pre-defined syndromes. In the pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72974338520fa2b8943ece7091efa786
https://hdl.handle.net/1871.1/26abd31f-1442-47e5-98b2-47c72baa2b6c