Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Erik Dietzel"'
Autor:
Anne Sadewasser, Erik Dietzel, Sven Michel, Michael Klüver, Markus Helfer, Tamara Thelemann, Richard Klar, Markus Eickmann, Stephan Becker, Frank Jaschinski
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 686-697 (2019)
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus. Here, we selected the host factor Niema
Externí odkaz:
https://doaj.org/article/308c7be2e7a44d74b79da85945b8925c
Autor:
Alexandra Kupke, Asisa Volz, Erik Dietzel, Astrid Freudenstein, Jörg Schmidt, Hosam Shams-Eldin, Sylvia Jany, Lucie Sauerhering, Verena Krähling, Michelle Gellhorn Serra, Christiane Herden, Markus Eickmann, Stephan Becker, Gerd Sutter
Publikováno v:
Vaccines, Vol 10, Iss 4, p 533 (2022)
The urgent need for vaccines against Ebola virus (EBOV) was underscored by the large outbreak in West Africa (2014–2016). Since then, several promising vaccine candidates have been tested in pre-clinical and clinical studies. As a result, two vacci
Externí odkaz:
https://doaj.org/article/c197fefc32064d6e8959d5b89150555f
Autor:
Marc Ringel, Anja Heiner, Laura Behner, Sandro Halwe, Lucie Sauerhering, Nico Becker, Erik Dietzel, Bevan Sawatsky, Larissa Kolesnikova, Andrea Maisner
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007733 (2019)
Formation of cytoplasmic inclusion bodies (IBs) is a hallmark of infections with non-segmented negative-strand RNA viruses (order Mononegavirales). We show here that Nipah virus (NiV), a bat-derived highly pathogenic member of the Paramyxoviridae fam
Externí odkaz:
https://doaj.org/article/0f1f554301014d779716b6c31c727a9f
Autor:
Francisco J. Zapatero-Belinchón, Erik Dietzel, Olga Dolnik, Katinka Döhner, Rui Costa, Barbara Hertel, Barbora Veselkova, Jared Kirui, Anneke Klintworth, Michael P. Manns, Stefan Pöhlmann, Thomas Pietschmann, Thomas Krey, Sandra Ciesek, Gisa Gerold, Beate Sodeik, Stephan Becker, Thomas von Hahn
Publikováno v:
Viruses, Vol 11, Iss 3, p 275 (2019)
Filoviruses infect a wide range of cell types with the exception of lymphocytes. The intracellular proteins cathepsin B and L, two-pore channel 1 and 2, and bona fide receptor Niemann–Pick Disease C1 (NPC1) are essential for the endosomal phase of
Externí odkaz:
https://doaj.org/article/09e97d310df645fc8c25124376b4d0a3
Autor:
Anja Bauer, Sebastian Neumann, Axel Karger, Ann-Kristin Henning, Andrea Maisner, Boris Lamp, Erik Dietzel, Linda Kwasnitschka, Anne Balkema-Buschmann, Günther M Keil, Stefan Finke
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97233 (2014)
Membrane envelopment and budding of negative strand RNA viruses (NSVs) is mainly driven by viral matrix proteins (M). In addition, several M proteins are also known to be involved in host cell manipulation. Knowledge about the cellular targets and de
Externí odkaz:
https://doaj.org/article/3a0c9947ae0b4b3eb3711b79c4dd52a3
Autor:
Verena Krähling, Stephanie Erbar, Alexandra Kupke, Sara S. Nogueira, Kerstin C. Walzer, Hendrik Berger, Erik Dietzel, Sandro Halwe, Cornelius Rohde, Lucie Sauerhering, Letícia Aragão-Santiago, Jorge Moreno Herrero, Sonja Witzel, Heinrich Haas, Stephan Becker, Ugur Sahin
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy.
Emerging and re-emerging viruses, such as Zaire Ebola virus (EBOV), pose a global threat and require immediate countermeasures, including the rapid development of effective vaccines that are easy to manufacture. Synthetic self-amplifying RNAs (saRNAs
Autor:
Markus Eickmann, Anne Sadewasser, Tamara Thelemann, Frank Jaschinski, Sven Michel, Michael Klüver, Erik Dietzel, Stephan Becker, Richard Klar, Markus Helfer
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 686-697 (2019)
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 686-697 (2019)
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus. Here, we selected the host factor Niema
Autor:
Lucie Sauerhering, Bevan Sawatsky, Sandro Halwe, Laura Behner, Marc Ringel, Nico Becker, Andrea Maisner, Erik Dietzel, Anja Heiner, Larissa Kolesnikova
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 4, p e1007733 (2019)
PLoS Pathogens, Vol 15, Iss 4, p e1007733 (2019)
Formation of cytoplasmic inclusion bodies (IBs) is a hallmark of infections with non-segmented negative-strand RNA viruses (order Mononegavirales). We show here that Nipah virus (NiV), a bat-derived highly pathogenic member of the Paramyxoviridae fam
Autor:
Lucie Sauerhering, Judith Hoppe, Erik Dietzel, Stephan Becker, Thorsten Stiewe, Christin Peteranderl, Achim D. Gruber, Biruta Witte, Alexandra Kupke, Susanne Herold, Nina Hofmann, Andrea Nist, Tobias Zimmermann, Alexander Goesmann, Ludger Fink, Stefan Gattenloehner, Lars Meier
Publikováno v:
The European Respiratory Journal
article-version (AM) Accepted Manuscript
article-version (AM) Accepted Manuscript
Rationale While severe coronavirus infections, including Middle East respiratory syndrome coronavirus (MERS-CoV) cause lung injury with high mortality rates, protective treatment strategies are not approved for clinical use. Objectives We elucidated
Autor:
Stephan Becker, Lea C Beltzig, Bevan Sawatsky, Asisa Volz, Verena Krähling, Veronika von Messling, Olga Dolnik, Erik Dietzel, Gerd Sutter, Rebecca Schmidt
Publikováno v:
npj Vaccines
NPJ Vaccines
npj Vaccines, Vol 3, Iss 1, Pp 1-10 (2018)
NPJ Vaccines
npj Vaccines, Vol 3, Iss 1, Pp 1-10 (2018)
The recent Ebola virus outbreak has highlighted the therapeutic potential of antisera and renewed interest in this treatment approach. While human convalescent sera may not be readily available in the early stages of an outbreak, antisera of animal o