Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Erik C. Rocheford"'
Autor:
Rui Zheng, Douglas C. Bauer, Justin Yik Ching Mao, Qian Liu, Vasumathy Miduturu, Richard Zessis, Frédéric Zecri, Qingming Zhu, Panos Hatsis, Benjamin Hoogheem, Xin Chen, Ryan Scott Streeper, Sejal Patel, Rohit Duvadie, Tyler Harrison, Erik C. Rocheford, Alina Berdichevsky
Publikováno v:
ACS Med Chem Lett
[Image: see text] Diacylglycerol O-acyltransferase 1 (DGAT1) inhibitor Pradigastat (1) was shown to be effective at decreasing postprandial triglyceride levels in a patient population with familial chylomicronemia syndrome (FCS). Although pradigastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20abe8c9bf3e5908861a37faee171af8
https://doi.org/10.1021/acsmedchemlett.9b00117
https://doi.org/10.1021/acsmedchemlett.9b00117
Autor:
Taeyoung Yoon, Kevin B. Clairmont, Yongjin Gong, Qing Yang, Marlene Juedes, Andrew Tyler, Michael H. Serrano-Wu, Theresa Cosker, Moo Je Sung, Tara L. Mullarkey, Lisha Li, Gary M. Coppola, Alan D. Neubert, Thomas Daniels, Erik C. Rocheford, Renee Commerford, Ying Hou, Ricardo E. Chatelain, Monish Jain, Brian K. Hubbard
Publikováno v:
ACS Medicinal Chemistry Letters. 3:411-415
High DGAT1 expression levels in the small intestine highlight the critical role this enzyme plays in nutrient absorption. Identification of inhibitors which predominantly inhibit DGAT1 in the gut is an attractive drug discovery strategy with anticipa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d7df1bc35c3873046f61a201f435be
https://doi.org/10.1021/ml3000512
https://doi.org/10.1021/ml3000512
Autor:
Didier Laurent, John S. Gounarides, Thomas Edward Hughes, Xue Li, Farid Sari-Sarraf, S. Renee Commerford, Erik C. Rocheford, Tara L. Mullarkey, Suzanne E. Dorfman, Erica A. Hirsch
Publikováno v:
Obesity. 17:1200-1207
Dietary trans-fatty acids are associated with increased risk of cardiovascular disease and have been implicated in the incidence of obesity and type 2 diabetes mellitus (T2DM). It is established that high-fat saturated diets, relative to low-fat diet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3eb0799a3f663817fb28347f038a41
https://doi.org/10.1038/oby.2008.662
https://doi.org/10.1038/oby.2008.662
Autor:
Erik C. Rocheford, Tara L. Mullarkey, Nico Mitro, Xue Li, Enrique Saez, Patrick Kennedy, S. Renee Commerford, Leo Vargas, Puiying A. Mak, Suzanne E. Dorfman
Publikováno v:
Molecular Endocrinology. 21:3002-3012
The liver X receptors (LXRalpha and beta) are nuclear receptors that coordinate carbohydrate and lipid metabolism. Treatment of insulin-resistant mice with synthetic LXR ligands enhances glucose tolerance, inducing changes in gene expression expected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca83b4b12db042abcb09b38fd34fd3a
https://doi.org/10.1210/me.2007-0156
https://doi.org/10.1210/me.2007-0156
Building a Better Understanding of Basic Mechanical Principles Through Analysis of the Vertical Jump
Publikováno v:
Strength and Conditioning Journal. 28:70-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9375ba056de54771bf295e8557badef4
https://doi.org/10.1519/00126548-200608000-00012
https://doi.org/10.1519/00126548-200608000-00012
Autor:
Jason C. Koval, Erik C. Rocheford, Dionysios A. Antonopoulos, Edward Ulman, Michael A. Pellizzon, Douglas S. Compton, Matthew R. Ricci
Publikováno v:
Gastroenterology. 148:S-540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d14f01bb9badd2fad7bfa2297931c1
https://doi.org/10.1016/s0016-5085(15)31812-6
https://doi.org/10.1016/s0016-5085(15)31812-6
Publikováno v:
Medicine & Science in Sports & Exercise. 38:S264-S265
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::235c2e2c91e2ba5de8620a391ad94288
https://doi.org/10.1249/00005768-200605001-02028
https://doi.org/10.1249/00005768-200605001-02028
Autor:
Xue Li, Erik C. Rocheford, S. Renee Commerford, Thomas Edward Hughes, John S. Gounarides, Erica A. Hirsch, Farid Sari-Sarraf, Suzanne E. Dorfman, Didier Laurent, Tara L. Mullarkey
Publikováno v:
Obesity. 17:1474-1474
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfcd839f5519c375211c33f953c8f10
https://doi.org/10.1038/oby.2009.144
https://doi.org/10.1038/oby.2009.144