Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Erik C, Wiener"'
Autor:
Shi-Yuan Cheng, Hsin-I Ma, Erik C. Wiener, Jann N. Sarkaria, Shih-Hwa Chiou, Frank S. Lieberman, Haizhong Feng, Kun-wei Liu, Raghvendra S. Sengar, Paul A. Schornack, Bo Hu, Jia-Jean Yiin
Supplementary Data from ZD6474, a Multitargeted Inhibitor for Receptor Tyrosine Kinases, Suppresses Growth of Gliomas Expressing an Epidermal Growth Factor Receptor Mutant, EGFRvIII, in the Brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8663f5bcf3cbb4de8ce8a0c39390eb56
https://doi.org/10.1158/1535-7163.22485650.v1
https://doi.org/10.1158/1535-7163.22485650.v1
Autor:
Shi-Yuan Cheng, Hsin-I Ma, Erik C. Wiener, Jann N. Sarkaria, Shih-Hwa Chiou, Frank S. Lieberman, Haizhong Feng, Kun-wei Liu, Raghvendra S. Sengar, Paul A. Schornack, Bo Hu, Jia-Jean Yiin
Epidermal growth factor receptor (EGFR) vIII is a mutated EGFR that is frequently overexpressed in glioblastomas and implicated in response to receptor tyrosine kinase inhibitors. In this study, we investigate the effect of ZD6474 (ZACTIMA, vandetani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c105545f57d52875c69f7082fe017af2
https://doi.org/10.1158/1535-7163.c.6532040
https://doi.org/10.1158/1535-7163.c.6532040
Autor:
Marie-Caline Abadjian, Erik C. Wiener, Arnold L. Rheingold, Po Yee Leung, Raghvendra S. Sengar, Douglas B. Grotjahn, Curtis E. Moore, Christie Schulte, Christoffel van Niekerk, Luce Vander Elst
Publikováno v:
Inorganic Chemistry
Inorganic chemistry, vol 53, iss 13
Inorganic chemistry, vol 53, iss 13
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) include an effective concentration of paramagnetic or superparamagnetic ions at the target to be imaged. We report the concise synthesis and characteriza
Publikováno v:
The Journal of organic chemistry. 81(15)
Diazo transfer reactions on Behera’s amine and its next-generation analogue formed G0 and G1 azide dendrons bearing three and nine tert-butyl-protected esters, respectively. The utility of the new dendrons was demonstrated by copper-catalyzed azide
Autor:
Charles M. Laymon, Erik C. Wiener, Matthew J. Oborski, Frank S. Lieberman, James M. Mountz, Fernando E. Boada, Denise Davis, Vincent Lee
Publikováno v:
Magnetic Resonance Imaging. 30:1268-1278
We evaluate novel magnetic resonance imaging (MRI) and positron emission tomography (PET) quantitative imaging biomarkers and associated multimodality, serial-time-point analysis methodologies, with the ultimate aim of providing clinically feasible,
Autor:
Archana Nigam, Zhihua Huang, Douglas M. Potter, Marie-Caline Abadjian, Douglas B. Grotjahn, Erik C. Wiener, Raghvendra S. Sengar
Publikováno v:
Investigative Radiology. 45:641-654
We aimed to develop a directly detected magnetic resonance imaging (MRI) contrast agent for use with high fields based on a nanoscale fluorinated dendrimer-based platform for F MRI and overcome some of the problems with F MRI.The dendrimers were prep
Autor:
Raghvendra S. Sengar, Norma Arbujas, Erik C. Wiener, William H. Chambers, Laima Spokauskiene, Daniel P. Steed, Patricia Griffin
Publikováno v:
Magnetic Resonance in Medicine. 62:599-606
Dendritic cells (DCs) are the most effective antigen-presenting cells (APCs) and are used in a variety of immunotherapeutic approaches. Adoptive cellular immunotherapy (ACI) of cancer using DCs has attracted much interest due to their capacity to pro
Publikováno v:
Polyhedron. 28:1525-1531
Modified 6-amino-6-methylperhydro-1,4-diazepinetetraacetic acid (AAZTA) ligands with a hydroxyl arm have been synthesized and characterized. The crystal structures of its lanthanide complexes, determined by single crystal X-ray crystallography, show
Publikováno v:
Magnetic Resonance Imaging. 25:14-34
We tested the hypothesis that partial volume effects due to poor in-plane resolution and/or low temporal resolution used in clinical dynamic contrast-enhanced magnetic resonance imaging results in erroneous diagnostic information based on inaccurate
Publikováno v:
Investigative Radiology. 38:662-668
Rationale and objectives: Dendrimer-based magnetic resonance imaging (MRI) contrast agents offer many advantages including high levels of amplification. The objective of this research was to test the adequacy and viability of a new family of dendrime