Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Erik C, Andersen"'
Autor:
Jessica Knox, Andrew R. Burns, Brittany Cooke, Savina R. Cammalleri, Megan Kitner, Justin Ching, Jack M. P. Castelli, Emily Puumala, Jamie Snider, Emily Koury, J. B. Collins, Salma Geissah, James J. Dowling, Erik C. Andersen, Igor Stagljar, Leah E. Cowen, Mark Lautens, Inga Zasada, Peter J. Roy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Left unchecked, plant-parasitic nematodes have the potential to devastate crops globally. Highly effective but non-selective nematicides are justifiably being phased-out, leaving farmers with limited options for managing nematode infestation
Externí odkaz:
https://doaj.org/article/609af50dc9664af39474ef0017566555
Autor:
J.B. Collins, Skyler A. Stone, Emily J. Koury, Anna G. Paredes, Fiona Shao, Crystal Lovato, Michael Chen, Richelle Shi, Anwyn Y. Li, Isa Candal, Khadija Al Moutaa, Nicolas D. Moya, Erik C. Andersen
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 25, Iss , Pp 100556- (2024)
Benzimidazole (BZ) anthelmintics are among the most important treatments for parasitic nematode infections in the developing world. Widespread BZ resistance in veterinary parasites and emerging resistance in human parasites raise major concerns for t
Externí odkaz:
https://doaj.org/article/a2b854f4d1dc4ffc83d524e4f4ba01c6
Autor:
Amanda O Shaver, Isabella R Miller, Etta S Schaye, Nicolas D Moya, J B Collins, Janneke Wit, Alyssa H Blanco, Fiona M Shao, Elliot J Andersen, Sharik A Khan, Gracie Paredes, Erik C Andersen
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012245 (2024)
Albendazole (a benzimidazole) and ivermectin (a macrocyclic lactone) are the two most commonly co-administered anthelmintic drugs in mass-drug administration programs worldwide. Despite emerging resistance, we do not fully understand the mechanisms o
Externí odkaz:
https://doaj.org/article/349a789c79814e0b82ff43d3f87c3bf2
Autor:
Nicolas D. Moya, Lewis Stevens, Isabella R. Miller, Chloe E. Sokol, Joseph L. Galindo, Alexandra D. Bardas, Edward S. H. Koh, Justine Rozenich, Cassia Yeo, Maryanne Xu, Erik C. Andersen
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background The nematode Caenorhabditis briggsae has been used as a model in comparative genomics studies with Caenorhabditis elegans because of their striking morphological and behavioral similarities. However, the potential of C. briggsae f
Externí odkaz:
https://doaj.org/article/eeaf2d9a03654917a1194cead3f48158
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 20, Iss , Pp 89-96 (2022)
Parasitic nematode infections cause an enormous global burden to both humans and livestock. Resistance to the limited arsenal of anthelmintic drugs used to combat these infections is widespread, including benzimidazole (BZ) compounds. Previous studie
Externí odkaz:
https://doaj.org/article/43603e10e8634a428d854dc1b494ae35
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Gene expression links genomic variation to organismal trait differences. Here, the authors identify regulatory loci underlying gene expression variation in C. elegans and demonstrate how this variation could impact other complex traits.
Externí odkaz:
https://doaj.org/article/8f00fc9a243c4524aec86c42d4e755fe
Autor:
Amanda O Shaver, Janneke Wit, Clayton M Dilks, Timothy A Crombie, Hanchen Li, Raffi V Aroian, Erik C Andersen
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011285 (2023)
Treatment of parasitic nematode infections in humans and livestock relies on a limited arsenal of anthelmintic drugs that have historically reduced parasite burdens. However, anthelmintic resistance (AR) is increasing, and little is known about the m
Externí odkaz:
https://doaj.org/article/cb906620849a417a907ad66e08d9b134
Autor:
Abhinaya Venkatesan, Pablo D Jimenez Castro, Arianna Morosetti, Hannah Horvath, Rebecca Chen, Elizabeth Redman, Kayla Dunn, James Bryant Collins, James S Fraser, Erik C Andersen, Ray M Kaplan, John S Gilleard
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011146 (2023)
Ancylostoma caninum is an important zoonotic gastrointestinal nematode of dogs worldwide and a close relative of human hookworms. We recently reported that racing greyhound dogs in the USA are infected with A. caninum that are commonly resistant to m
Externí odkaz:
https://doaj.org/article/9d709edce2484e77ba4427c79d0353f3
Autor:
Ida L. Barlow, Luigi Feriani, Eleni Minga, Adam McDermott-Rouse, Thomas James O’Brien, Ziwei Liu, Maximilian Hofbauer, John R. Stowers, Erik C. Andersen, Siyu Serena Ding, André E. X. Brown
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
A multiplexed machine-vision-based tracking system enables the high-content analysis of C. elegans behavior in several 96-well plates at a time and shows its utility for comparisons across multiple genotypes and upon drug treatment, tackling the bott
Externí odkaz:
https://doaj.org/article/c5ad7234fda74b00af76036124539bca
Autor:
Janneke Wit, Clayton M Dilks, Gaotian Zhang, Karen S Kim Guisbert, Stefan Zdraljevic, Eric Guisbert, Erik C Andersen
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0286473 (2023)
Anthelmintic drugs are used to treat parasitic roundworm and flatworm infections in humans and other animals. Caenorhabditis elegans is an established model to investigate anthelmintics used to treat roundworms. In this study, we use C. elegans to ex
Externí odkaz:
https://doaj.org/article/2907aa0343684d1e9cc9aed2285f07b4