Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Erik Björk"'
Publikováno v:
Pharmaceutical Research. 26:1618-1625
To create improved pharmaceutical formulations for nasal and sublingual administration of desmopressin and investigate their pharmacokinetic profiles in comparison with a commercial nasal liquid spray and finally to evaluate the volunteers' opinions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce6da4a4c6bfb1b234fa8e3d46e3cd3
https://doi.org/10.1007/s11095-009-9871-9
https://doi.org/10.1007/s11095-009-9871-9
Publikováno v:
Journal of Pharmaceutical Sciences. 97:3855-3864
The residence time in the nasal cavity can be prolonged by dry particles that absorb water and subsequently increase the viscosity of the mucus layer. A novel nasal drug delivery system based on interactive mixtures has previously been developed, whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60224e7bfdfa0d9121f1d71157367e57
https://doi.org/10.1002/jps.21279
https://doi.org/10.1002/jps.21279
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 67:370-376
The aim of this study was to investigate whether mucoadhesive interactive mixtures can be created using carrier particles in a size range appropriate for nasal administration, i.e. 10-50 microm. We also used theoretical models to investigate if homog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c272a6cec5b615551a25cb29b258b4e
https://doi.org/10.1016/j.ejpb.2007.03.006
https://doi.org/10.1016/j.ejpb.2007.03.006
Publikováno v:
Journal of Drug Delivery Science and Technology. 17:267-271
The objective was to investigate the transport of dihydroergotamine (DHE) across porcine nasal respiratory and olfactory mucosa and to evaluate the absorption enhancing effect of a novel dry pow ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4bb7b8c4ca8313360eeeb2cd7477c61
https://doi.org/10.1016/s1773-2247(07)50094-8
https://doi.org/10.1016/s1773-2247(07)50094-8
Publikováno v:
Pharmaceutical Research. 23:565-572
The aim of this study was to quantify the olfactory transfer of morphine to the brain hemispheres by comparing brain tissue and plasma morphine levels after nasal administration with those after intravenous administration. Morphine (1.0 mg/kg body we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731f3f7e95295090627ae4b550f2723f
https://doi.org/10.1007/s11095-006-9534-z
https://doi.org/10.1007/s11095-006-9534-z
Autor:
Erik Björk, Björn Jansson
Publikováno v:
Journal of Drug Targeting. 10:379-386
Nasal administration of a 3 kDa fluorescein dextran (FD3) solution to rats resulted in transcellular absorption across the olfactory epithelium and transfer to the olfactory bulb within 15 min. After entering the lamina propria, FD3 was transferred i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffc1864d6192136088ec5ecce8c0d69
https://doi.org/10.1080/1061186021000001823
https://doi.org/10.1080/1061186021000001823
Publikováno v:
European Journal of Pharmaceutical Sciences. 14:75-80
The aim of this study was to investigate the levels of [(3)H]dopamine in blood, the cerebrospinal fluid (CSF) and brain tissue samples in rats and to find out whether the drug is transferred along the olfactory pathway to the central nervous system f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74dc66f90dbe757d6b6849cdd26be4d
https://doi.org/10.1016/s0928-0987(01)00151-8
https://doi.org/10.1016/s0928-0987(01)00151-8