Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Erik B. Kistler"'
Autor:
Nathalia J. D. Moreira, Fernando dos Santos, Joyce B. Li, Federico Aletti, Maria Claudia C. Irigoyen, Erik B. Kistler
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Preserving vascular function is crucial for preventing multiorgan failure and death in ischemic and low-pressure states such as trauma/hemorrhagic shock (T/HS). It has recently been reported that inhibiting circulating proteases released fro
Externí odkaz:
https://doaj.org/article/40235be00cb54a1c9a78b986c803d977
Autor:
Fernando Dos Santos, Joyce B. Li, Nathalia Juocys, Rafi Mazor, Laura Beretta, Nicole G. Coufal, Michael T. Y. Lam, Mazen F. Odish, Maria Claudia Irigoyen, Anthony J. O’Donoghue, Federico Aletti, Erik B. Kistler
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Introduction: Infection by SARS-CoV-2 and subsequent COVID-19 can cause viral sepsis. We investigated plasma protease activity patterns in COVID-19-induced sepsis with bacterial superinfection, as well as plasma proteomics and peptidomics in order to
Externí odkaz:
https://doaj.org/article/62521e5602074710bd201329d585283e
Autor:
Cynthia R. Muller, Vasiliki Courelli, Alfredo Lucas, Alexander T. Williams, Joyce B. Li, Fernando Dos Santos, Clayton T. Cuddington, Savannah R. Moses, Andre F. Palmer, Erik B. Kistler, Pedro Cabrales
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Traumatic brain injury (TBI) is often accompanied by hemorrhage, and treatment of hemorrhagic shock (HS) after TBI is particularly challenging because the two therapeutic treatment strategies for TBI and HS often conflict. Ischemia/reperfusi
Externí odkaz:
https://doaj.org/article/498e933377124b19800d64b418baa677
Autor:
Daniele Braga, Matteo Barcella, Antoine Herpain, Federico Aletti, Erik B. Kistler, Bernardo Bollen Pinto, Karim Bendjelid, Cristina Barlassina
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-14 (2019)
Abstract Background Septic shock (SS) and cardiogenic shock (CS) are two types of circulatory shock with a different etiology. Several studies have described the molecular alterations in SS patients, whereas the molecular factors involved in CS have
Externí odkaz:
https://doaj.org/article/d927ca9e6c8e4e21844b142c471af4cd
Autor:
Rafi Mazor, PhD, Fernando Dos Santos, PhD, Joyce B. Li, MSc, Federico Aletti, PhD, Geert Schmid-Schonbein, PhD, Erik B. Kistler, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 7, p e0469 (2021)
OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock. Incr
Externí odkaz:
https://doaj.org/article/008a808c51d34d4facd3cbd11a781ae3
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Microcirculatory preservation is essential for patient recovery from hemorrhagic shock. In hemorrhagic shock, microcirculatory flow and pressure are greatly reduced, creating an oxygen debt that may eventually become irreversible. During shock, tissu
Externí odkaz:
https://doaj.org/article/d801dd469d504ab9aaeee024f2d5fcfd
Autor:
Yonggang Ma, Taylor Zabell, Alexandra Creasy, Xiaoyuan Yang, Victor Chatterjee, Nuria Villalba, Erik B. Kistler, Mack H. Wu, Sarah Y. Yuan
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Gut ischemia/reperfusion (I/R) injury is a common clinical problem associated with significant mortality and morbidities that result from systemic inflammation and remote organ dysfunction, typically acute lung injury. The mechanisms underlying the d
Externí odkaz:
https://doaj.org/article/81dd12ae3d7741d88983bfc7018d6c55
Autor:
Elisa Maffioli, Zhenze Jiang, Simona Nonnis, Armando Negri, Valentina Romeo, Christopher B. Lietz, Vivian Hook, Giuseppe Ristagno, Giuseppe Baselli, Erik B. Kistler, Federico Aletti, Anthony J. O’Donoghue, Gabriella Tedeschi
Publikováno v:
Molecules, Vol 25, Iss 18, p 4071 (2020)
Proteomic technologies have identified 234 peptidases in plasma but little quantitative information about the proteolytic activity has been uncovered. In this study, the substrate profile of plasma proteases was evaluated using two nano-LC-ESI-MS/MS
Externí odkaz:
https://doaj.org/article/56f4355b40ca4683aca2643805949002
Autor:
Amy G. Tsai, Beatriz Y. Salazar Vázquez, Pedro Cabrales, Erik B. Kistler, Daniel M. Tartakovsky, Shankar Subramaniam, Seetharama A. Acharya, Marcos Intaglietta
Publikováno v:
Journal of Functional Biomaterials, Vol 5, Iss 4, Pp 232-245 (2014)
At least a third of the blood supply in the world is used to transfuse 1–2 units of packed red blood cells for each intervention and most clinical trials of blood substitutes have been carried out at this level of oxygen carrying capacity (OCC) res
Externí odkaz:
https://doaj.org/article/25adec29b8984995957d25682ea8a0b4
Autor:
Meital Cohen-Mazor, Rafi Mazor, Batya Kristal, Erik B. Kistler, Inbal Ziv, Judith Chezar, Shifra Sela
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Heparin is known to have anti-inflammatory effects, yet the mechanisms are not completely understood. In this study, we tested the hypothesis that heparin has a direct effect on activated polymorphonuclear leukocytes (PMNLs), changing their activatio
Externí odkaz:
https://doaj.org/article/66425e3c839d4f2fb2fffc83f74e253f