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pro vyhledávání: '"Erik Arango Gutierrez"'
Autor:
Valerie, Schmieder, Juergen, Fieder, Raphael, Drerup, Erik Arango, Gutierrez, Carina, Guelch, Jessica, Stolzenberger, Mihaela, Stumbaum, Volker Steffen, Mueller, Fabian, Higel, Martin, Bergbauer, Kim, Bornhoefft, Manuel, Wittner, Petra, Gronemeyer, Christian, Braig, Michaela, Huber, Anita, Reisenauer-Schaupp, Markus Michael, Mueller, Mark, Schuette, Sebastian, Puengel, Benjamin, Lindner, Moritz, Schmidt, Patrick, Schulz, Simon, Fischer
Publikováno v:
Journal of Biotechnology. 349:53-64
In recent years, acceleration of development timelines has become a major focus within the biopharmaceutical industry to bring innovative therapies faster to patients. However, in order to address a high unmet medical need even faster further acceler
Autor:
Andreas Unsoeld, David Mentrup, Elke Prade, Anne Zeck, Ingo Gorr, Fabian Stiefel, Erik Arango Gutierrez
Publikováno v:
Biotechnology and Bioengineering
A high degree of charge heterogeneity is an unfavorable phenomenon commonly observed for therapeutic monoclonal antibodies (mAbs). Removal of these impurities during manufacturing often comes at the cost of impaired step yields. A wide spectrum of po
Autor:
Marco Bocola, Hartmut Duefel, Anne-Maria Wallraf, Mehdi D. Davari, Thomas Meier, Erik Arango Gutierrez, Alexandra Balaceanu, Ulrich Schwaneberg
Publikováno v:
Biotechnology and Bioengineering. 115:2405-2415
Glucose oxidase (GOx) is of high industrial interest for glucose sensing because of its high β-d-glucose specificity. The efficient and specific electrochemical communication between the redox center and electrodes is crucial to ensure accurate gluc
Autor:
Thomas Meier, Hartmut Duefel, Erik Arango Gutierrez, Ulrich Schwaneberg, Hemanshu Mundhada, Marco Bocola
Publikováno v:
Biosensorsbioelectronics. 50
Glucose oxidase is an oxidoreductase exhibiting a high β- d -glucose specificity and high stability which renders glucose oxidase well-suited for applications in diabetes care. Nevertheless, GOx activity is highly oxygen dependent which can lead to