Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Erik A. Lundquist"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/17c5312060bb45eabf7437468dac7034
Autor:
Snehal S. Mahadik, Erik A. Lundquist
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: UNC-6/Netrin is a conserved bi-functional guidance cue which regulates dorsal-ventral axon guidance in C. elegans. In the Polarity/Protrusion model of UNC-6/Netrin mediated dorsal growth away from UNC-6/Netrin, The UNC-5 receptor first
Externí odkaz:
https://doaj.org/article/b20ef66b165349948a72d443ef161da7
Autor:
Matthew E. Ochs, Rebecca M. McWhirter, Robert L. Unckless, David M. Miller, Erik A. Lundquist
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract Migration of neuroblasts and neurons from their birthplace is central to the formation of neural circuits and networks. ETR-1 is the Caenorhabditis elegans homolog of the CELF1 (CUGBP, ELAV-like family 1) RNA-processing factor involved in ne
Externí odkaz:
https://doaj.org/article/e3294866cb8e4854be5337b17e648de7
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 7, Pp 2365-2376 (2020)
Neuroblast migration is a critical aspect of nervous system development (e.g., neural crest migration). In an unbiased forward genetic screen, we identified a novel player in neuroblast migration, the ETR-1/CELF1 RNA binding protein. CELF1 RNA bindin
Externí odkaz:
https://doaj.org/article/a6cd42beb45d463ba6ad0b5ae1637556
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1339-1353 (2019)
Regulation of luminal diameter is critical to the function of small single-celled tubes, of which the seamless tubular excretory canals of Caenorhabditis elegans provide a tractable genetic model. Mutations in several sets of genes exhibit the Exc ph
Externí odkaz:
https://doaj.org/article/9c15a539cbaf47639e5f70669550c93e
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 6, Pp 1885-1895 (2018)
During development, neuronal cells extend an axon toward their target destination in response to a cue to form a properly functioning nervous system. Rho proteins, Ras-related small GTPases that regulate cytoskeletal organization and dynamics, cell a
Externí odkaz:
https://doaj.org/article/9530b415d6f14566a9d5248ca6614c83
Autor:
Angelica E. Lang, Erik A. Lundquist
Publikováno v:
Journal of Developmental Biology, Vol 9, Iss 1, p 7 (2021)
Cell adhesion molecules and their extracellular ligands control morphogenetic events such as directed cell migration. The migration of neuroblasts and neural crest cells establishes the structure of the central and peripheral nervous systems. In C. e
Externí odkaz:
https://doaj.org/article/4a3b862bb3c449198b733dc102849776
Publikováno v:
bioRxiv
In the Polarity/Protusion model of growth cone migration away from the guidance cue UNC-6/Netrin, the UNC-5 receptor polarizes the VD growth cone such that filopodial protrusions are biased to the dorsal leading edge of the growth cone. UNC-5 also in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25c5ceefe02b6c29877952c34bf211d
https://europepmc.org/articles/PMC10245697/
https://europepmc.org/articles/PMC10245697/
Autor:
Snehal S. Mahadik, Erik A. Lundquist
Publikováno v:
Development. 150
In the polarity/protrusion model of growth cone repulsion from UNC-6/Netrin, UNC-6 first polarizes the VD growth cone via the UNC-5 receptor, and then regulates protrusion asymmetrically across the growth cone based on this polarity. Through the UNC-
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006998 (2017)
The guidance cue UNC-6/Netrin regulates both attractive and repulsive axon guidance. Our previous work showed that in C. elegans, the attractive UNC-6/Netrin receptor UNC-40/DCC stimulates growth cone protrusion, and that the repulsive receptor, an U
Externí odkaz:
https://doaj.org/article/a0b7d08eb935499fabdbf9a43044415b